The Barker Lab @thebarkerlabgroup.bsky.social · 02/09/2026Some more photos from the Aligning Science Across Parkinson’s (ASAP) meeting! 🧠🔬 A few snapshots from our time in Sweden last week, along with a throwback to the ASAP Annual Meeting in Barcelona back in June! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 01/09/2026Roger gave a talk on dopamine cell therapies to the Australian Hunters Parkinson's Society at their meeting last Friday. He was warmly welcomed by one of his very first fellows and now world leading clinician scientist in Parkinson's disease, Professor Simon Lewis who works out of Sydney! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 26/08/2026The ASAP team, led by Johan Jakobsson, met in Skanör this week to catch up on progress with their project exploring the role of transposons in PD. Roger was there too, along with colleagues & members of his team. Great to get everyone together, share updates and discuss where the project is going!🧬🔬 000
The Barker Lab @thebarkerlabgroup.bsky.social · 21/08/2026I’m really pleased to share the publication of our new paper in Communications Biology. This work was headed by Maha Alfaidi, building on research from her PhD - fantastic to see this now published! A huge congratulations to Maha and everyone involved🎉 Read here: doi.org/10.1038/s420...doi.orgEarly α-synuclein–mediated mitochondrial dysfunction in a human cell model of Parkinson’s disease dementia - Communications BiologyA human neuron model of Parkinson’s disease using α-synuclein fibrils is developed, replicating key pathology and mitochondrial gene dysregulation, and tested peptide inhibitors B36D and S62. 010
The Barker Lab @thebarkerlabgroup.bsky.social · 11/08/2026Roger was quoted in a newly published article highlighting the growing dangers of rogue clinics, fake stem cell therapies and unapproved injectables in PD. The @isscr.org has great guides to help people spot unlicensed and potentially dangerous therapies, worth a read. lnkd.in/gAs3BrvPparkinsonsinsights.comUnapproved stem cell clinics exploit hope and risk lives in the search for a Parkinson's cure | Parkinson's NewsThe promise of stem cells and anti ageing breakthroughs has created a massive market. Yet behind polished marketing lies a treacherous landscape of rogue clinics, unappr... 000
The Barker Lab @thebarkerlabgroup.bsky.social · 10/08/2026The Movers & Shakers Podcast have released their latest Parky Profile and this week it's with Professor Roger Barker 🧠 Listen to the full episode now wherever you get your podcasts 🎙️ Spotify: lnkd.in/g4Rv5MHK Apple Podcasts: lnkd.in/gbJ5qD7Dlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 000
The Barker Lab @thebarkerlabgroup.bsky.social · 10/08/2026A huge congratulations to our PhD student, Angelica, who has been selected for the Genevia Single-Cell Mentorship Program 2026 🎉 The program provides six months of expert mentorship (October–March), which Angelica will be using to support the analysis of her single-cell data! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 20/07/2026Great to catch up with Claire Clelland last Thursday! Claire worked with us a few years ago on research around neurogenesis as part of her PhD and MPhil. She is now at UCSF, where she's doing incredible research in gene editing with the potential to transform how we treat certain brain diseases. 000
The Barker Lab @thebarkerlabgroup.bsky.social · 16/07/2026Congratulations to our Academic Clinical Fellow, Rosana-Bristena Ionescu, on being awarded an ACT Research Grant for the IMUN-HD project! The project investigates the role of the immune system in Huntington’s disease using cutting-edge single-cell sequencing and advanced proteomic profiling. 030
The Barker Lab @thebarkerlabgroup.bsky.social · 13/07/2026Great to be at #ISSCR2026 in Montreal! Roger delivered a plenary lecture on the latest progress from stem cell trials for PD—an exciting step forward for the field. It was also fantastic to catch up with Zoe Hewitt (Regen CTC, UK) and Jihwan Song (Seoul). 000
The Barker Lab @thebarkerlabgroup.bsky.social · 09/07/2026A landmark study led by Lund University in collaboration with the University of Cambridge, reports the first clinical results from the STEM-PD trial. The study shows that transplanting stem cell-derived dopamine progenitor cells into the brain is feasible👏 🔗 www.nature.com/articles/s41... 010
The Barker Lab @thebarkerlabgroup.bsky.social · 09/07/2026Roger is in Montreal at the annual ISSCR meeting where he is discussing dopamine cell therapies in Parkinson's disease including the Lund-Cambridge Stem PD trial. He is giving a plenary talk on Saturday presenting the data from this and other published trials using this approach - exciting times! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 02/07/2026Congratulations to our PhD student Sophie on being awarded a completion grant from Newnham College, Cambridge. 🎓 This is a well-deserved recognition of her commitment, dedication, and excellent work as she enters the final stage of her doctoral research and prepares to submit her thesis this summer🌟 010
The Barker Lab @thebarkerlabgroup.bsky.social · 29/06/2026Roger joined international colleagues in Barcelona for the ASAP meeting to explore new ways of understanding what may go wrong in PD as we age. This could pave the way to an entirely new treatment approach for this condition. We're looking forward to seeing where this work leads! #CRNBarcelona2026 100
The Barker Lab @thebarkerlabgroup.bsky.social · 10/06/2026We're pleased to share our new article, "Safeguarding Advanced Therapies—The Dangers of Therapeutic Neuroabandonment: How Should We Ensure Patient Safety and Scientific Integrity When a Commercial Clinical Trial Sponsor Becomes Insolvent?" movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...movementdisorders.onlinelibrary.wiley.com 000
The Barker Lab @thebarkerlabgroup.bsky.social · 10/06/2026Episode 418 of The TogetherForSharon Podcast is now live on Spotify! Roger joined George, Sharon’s son, for a Q&A on stem cell therapies for Parkinson’s disease and the World Parkinson Congress. Listen here: open.spotify.com/episode/6qv6...open.spotify.comQ & A with Sharon's son, George. Episode 418 Special Guest Dr. Roger Barker, Stem Cell Therapies for Parkinson's disease and the World Parkinson CongressThe TogetherForSharon® Podcast · Episode 021
The Barker Lab @thebarkerlabgroup.bsky.social · 04/06/2026Roger and Claire Henchcliffe discuss the development, goals, and educational value of International Society for Stem Cell Research's new stem cell medicine course for Parkinson disease! Now live: www.neurologylive.com/view/inside-...neurologylive.comInside the Development of ISSCR’s New Parkinson Disease Stem Cell Program | NeurologyLive - Clinical Neurology News and Neurology Expert InsightsNeurologists Roger Barker, MBBS, MRCP, PhD, FMedSci, and Claire Henchcliffe, MD, DPhil, discuss the development, goals, and educational value of ISSCR's new stem cell medicine course for Parkinson dis... 051
The Barker Lab @thebarkerlabgroup.bsky.social · 29/05/2026Really pleased that our partnership with LSBU has helped us host 4 fantastic students for work experience placements over the last two years. Even better — 2 students have now gone on to fully funded PhDs 🎉 We are very proud of their achievements. Big thanks to Alison Alvarez for all her help! 020
The Barker Lab @thebarkerlabgroup.bsky.social · 28/05/2026Our report on the OXB-102/Axo-Lenti-PD trial had now been published in the Movement Disorders Journal 🎉 Thank you to all who contributed to the study and write up, and especially to the participants involved! movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...movementdisorders.onlinelibrary.wiley.comObservations on an Open‐Label Phase 1/2 Dopamine Gene Therapy Trial (OXB‐102/Axo‐Lenti‐PD) in People with Parkinson's DiseaseBackground SUNRISE-PD was a dose-escalating, phase 1/2 study investigating a second-generation lentiviral vector gene therapy delivering the genes for dopamine synthesis (OXB-102) to treat Parkinson... 010
The Barker Lab @thebarkerlabgroup.bsky.social · 28/05/2026Beyond the “Breakthrough” “I don’t think we need a cure. If you can slow it down by 50 percent and pick people up early on, you’ve probably done it.” A new article from The Initiative Magazine explores Roger's work, perspective, and the future of PD. 👇 theinitiativemagazine.com/en/article/r...theinitiativemagazine.comRoger Barker: Beyond the “Breakthrough”“I don’t think we need a cure,” neuroscientist Roger Barker said. “If you can slow it down by 50 percent and pick people up early on, you’ve probably done it.” 020
The Barker Lab @thebarkerlabgroup.bsky.social · 27/05/2026Huge congratulations to Roger on receiving two 2026 Editor of Distinction Awards from Springer Nature 🎉 He was recognised with both the Editorial Contribution Award and the Author Service Award, highlighting his dedication to authors, excellence in peer review, and commitment to advancing discovery. 010
The Barker Lab @thebarkerlabgroup.bsky.social · 27/05/2026Roger attended the departmental PI retreat on Thursday 21st May at Madingley hall in Cambridge. Great day was had by all as the department gels in its work and ambitions! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 26/05/2026A fantastic start to the 7th World Parkinson Congress in Phoenix, Arizona🌵A special moment seeing Roger open #WPC2026 as President of the WPC - and marking what will be his final duty in the role! We’re also very proud of our PhD student James Shonhard, who presented his poster at the congress 👏 010
The Barker Lab @thebarkerlabgroup.bsky.social · 26/05/2026Roger and Katie held a dissemination event last Tuesday 19th May for our FELL HD participants to present the results of the trial. The event was well received with some great questions! Thank you to all those who attended 👏 000
The Barker Lab @thebarkerlabgroup.bsky.social · 19/05/2026Great day at Cambridge Dementia Research Day on 28 April Zanna spoke about “can we leverage sleep to prevent dementia?” and Roger did a brilliant patient-facing interview that brought the human side of the research into focus! 100
The Barker Lab @thebarkerlabgroup.bsky.social · 18/05/2026Great to be in Edinburgh for the 39th EFI/BSHI Conference 2026! Roger gave a plenary lecture on dopamine cell therapies in Parkinson’s disease as part of the conference theme, “From Genes to Grafts: Where Innovation Meets Medicine.” More about the conference here: efi-conference.org 000
The Barker Lab @thebarkerlabgroup.bsky.social · 15/05/2026Today, on International Huntington’s Disease Awareness Day, our team is wearing purple for Juvenile HD and blue for Huntington’s Disease awareness💜💙 Learn more about HD and the support available through the Huntington’s Disease Association: www.hda.org.uk #InternationalHDAwarenessDay 012
The Barker Lab @thebarkerlabgroup.bsky.social · 14/05/2026A big thanks to everyone who joined us for this year’s Barker Lab retreat! Three great days of talks from across the groups, loads of useful feedback and discussion, a very competitive quiz, and an excellent pub dinner to finish things off 🍻 Already looking forward to the next one 🎉 000
The Barker Lab @thebarkerlabgroup.bsky.social · 05/05/2026Had a great time at the CCTU Neuroscience theme event on Thursday! Roger & Katie presented FELL-HD, Saeed shared STEM-PD, and Zanna showcased DORA-HD. It wrapped up with a really insightful panel discussion with trial participants. Such a great event—big thanks to Emma Cutting and the CCTU team 🎉 000
The Barker Lab @thebarkerlabgroup.bsky.social · 29/04/2026Exciting News: Roger has ranked 29 in UK and 208 in the world for the 2026 Edition of Best Scientists in the field of Neuroscience by Research.com!🎉 Summary of the statistics and trends:research.com/careers/worl...rt Full ranking for the UK: research.com/scientists-rankings/ne…research.comWorld Online Ranking of Best Neuroscientists – 2026 Report | Research.com 000
The Barker Lab @thebarkerlabgroup.bsky.social · 28/04/2026Excited to share that our team is joining ASAP CRN @asapresearch.parkinsonsroadmap.org! We look forward to collaborating with scientists globally to catalyze breakthroughs in Parkinson’s & accelerate discoveries that lead to new treatments. Explore more: asapcrn.org #ParkinsonsDisease 151
The Barker Lab @thebarkerlabgroup.bsky.social · 22/04/2026Roger is giving a plenary lecture today on dopamine cell therapies in Parkinson's disease at 39th EFI/BSHI Conference 2026 in Edinburgh! From Genes to Grafts: Where Innovation meets Medicine 🔬 efi-conference.org 000
The Barker Lab @thebarkerlabgroup.bsky.social · 17/04/2026We are delighted to announce the publication of “Stem cell treatments and Parkinson's disease: Science and misconceptions” in the Journal of Parkinson’s Disease. The article by Athena Stamper, Harry Bulstrode and Roger Barker can be found here: doi.org/10.1177/1877...doi.orgStem cell treatments and Parkinson's disease: Science and misconceptions - Athena Stamper, Harry Bulstrode, Roger A Barker, 2026Parkinson's disease (PD) is a common neurodegenerative disorder associated with the accumulation of alpha-synuclein in Lewy bodies and Lewy neurites, as we... 000
The Barker Lab @thebarkerlabgroup.bsky.social · 13/04/2026Welcome Rosana-Bristena Ionescu to the Barker Lab 🎉 Bristena will be joining us as a Clinical Research Fellow for the next 2 years! She will do a joint project between the Barker and Jones labs using cutting-edge single-cell RNA sequencing to explore how the immune system shapes the course of HD. 000
The Barker Lab @thebarkerlabgroup.bsky.social · 10/04/2026Check out this great new webinar by Huntington's Disease Foundation featuring a presentation from Zanna Voysey 🎉 The HDF have just released a new webinar episode called What Your Blood Tells Us: The Science Behind HD Biomarkers Avaliable now on YouTube: www.youtube.com/watch?v=llim...youtube.comWhat Your Blood Tells Us: The Science Behind HD Biomarkers, 3/24/2026; Lauren Byrne and Zanna VoyseyYouTube video by Huntington's Disease Foundation 000
The Barker Lab @thebarkerlabgroup.bsky.social · 30/03/2026The Cambridge Clinical Trials Unit Neuroscience Theme Event is back 🎉 Join online or in person on Thursday 30th April 13:00-16:00, to hear results from completed trials, flash presentations, and a panel discussion with trial participants! Please register here: www.eventbrite.co.uk/e/neuroscien... 000
The Barker Lab @thebarkerlabgroup.bsky.social · 27/03/2026Roger was honoured today to give a talk virtually at the Cambridge Nanjing forum on cell therapies for Parkinson's disease! 000
The Barker Lab @thebarkerlabgroup.bsky.social · 26/03/2026Check out this 3D image of neurons created by our PhD student Jana! The image contains striatal neurons after 21 days in vitro expressing thyroxin hydroxylase (in green), cell nucleus (in blue), neuronal markers (red and cyan). Thyroxin hydroxylase plays a crucial role in the synthesis of dopamine. 010
The Barker Lab @thebarkerlabgroup.bsky.social · 24/03/2026Last Wednesday Roger did a talk on the value and misconceptions of dopamine cell replacement therapy as a potential treatment for Parkinson’s disease! To view the talk please see here: www.vumedi.com/video/parkin... (the link will only work for registered users but creating an account is free)vumedi.comParkinson Disease Cell Therapy: What Stem Cell-Derived Dopamine Neurons Can and Cannot DoA video from Roger Barker, posted on Mar 18, 2026. 000
The Barker Lab @thebarkerlabgroup.bsky.social · 23/03/2026Today is #HDGratitudeDay 💙Celebrating the partnership between families, scientists and clinical professionals to advance treatments for HD! We want to take a moment to recognise incredible families and participants who contribute to research—thank you for everything you do. ehdn.org/hd-gratitude...ehdn.orgHD Gratitude Day: 23 March 2026 – European Huntington's Disease Network 010
The Barker Lab @thebarkerlabgroup.bsky.social · 20/03/2026Excited to announce that we have been successfully awarded the @ehdn-news.bsky.social EHDN Lesley Jones Seed Fund Program 🎉 Using this fund, we will explore the possibility that transposable elements, normally silent parts of the human genome, become activated in brain cells in Huntington's disease! 010
The Barker Lab @thebarkerlabgroup.bsky.social · 20/03/2026The Tulip Fun Run and Walk is Back 🌷🏃 Get ready to run, walk, and have fun while supporting the Parkinson's UK Cambridge Branch at the Tulip Fun Run 2026. Our PhD student James Shonhard helped organise the event! See here how to register and fundraise: parkinsonscambridge.wordpress.com/tfr2026/ 000
The Barker Lab @thebarkerlabgroup.bsky.social · 18/03/2026A special Cambridge moment: Angelica train-bearing for the Chancellor's installation at senate house 🎓💐 Chris Smith, Lord Smith of Finsbury, has been formally installed as the 109th Chancellor of the University of Cambridge. Watch the full 40-minute ceremony: www.youtube.com/watch?v=LmKE...youtube.comThe New Chancellor of the University of Cambridge Installation CeremonyYouTube video by Cambridge University 001
The Barker Lab @thebarkerlabgroup.bsky.social · 13/03/2026I am proud to have presented in the new open-access @isscr.org course, Stem Cell Medicine: Parkinson's Disease, jointly provided with Harvard Medical School! Six modules explore stem cell therapies for PD. Plus a powerful conversation with a clinical trial participant. invt.io/1bxbvu0b8p7invt.ioI am a presenter in the ISSCR Continuing Education Course.Learn more. 151
The Barker Lab @thebarkerlabgroup.bsky.social · 12/03/2026I am excited to announce that I am a member of the @isscr.org ISSCR Education Committee! Learn more about our work and my fellow colleagues: invt.io/1lxbsu0i835invt.ioI am a member of the ISSCR Education CommitteeLearn more. 021
The Barker Lab @thebarkerlabgroup.bsky.social · 11/03/2026Huge congratulations to Saeed for smashing the Cambridge Half Marathon with an incredible 1:18 finish time! 🏃♂️🔥 000
The Barker Lab @thebarkerlabgroup.bsky.social · 09/03/2026Quick clinic update: Our Wednesday Huntington's Disease clinics are changing from full days to half days (9am - 12.30pm) from mid April 2026! Any questions please get in touch with our HD clinic coordinator. 000
The Barker Lab @thebarkerlabgroup.bsky.social · 03/03/2026The road ahead for uniQure: FDA says more data needed for AMT-130 gene therapy. On March 2026, uniQure shared in an update that current Phase 1/2 data weren’t enough for the agency. A new randomized, sham-controlled trial may be required. Read the full article here: en.hdbuzz.net/the-road-ahe...en.hdbuzz.netThe road ahead for uniQure: FDA says more data needed for AMT-130 gene therapy – HDBuzz 000
The Barker Lab @thebarkerlabgroup.bsky.social · 19/02/2026We kindly received Watch your step, Mr Parkinson! by Frank Snowy Stinson This book is a personal story of life with Parkinson’s. It is educational, encouraging and honest, touching on many issues of relevance to all those who are impacted by 'Parkee'. Find the book here: www.watchyourstep.com.au 000
The Barker Lab @thebarkerlabgroup.bsky.social · 16/02/2026Our annual Parkinson's Disease Open day was on Saturday 14th February, which was a great success 🎉 We had talks about ongoing research projects, ways to get involved, and a patient perspective. A huge thank you to everyone involved with set up, speakers and all who attended!! 001