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Amir, PharmD

@theamirimani.bsky.social
2.7K followers 722 following 295 posts

I talk about drugs, diseases, drugs, misinformation, and drugs. Opinions mine and not particularly good.

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Amir, PharmD @theamirimani.bsky.social · 25/09/2026
This is an excellent article and relevant for pharmacists as well. My practice really benefits from AI, but how I use vs how students use it is *very* different.
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Amir, PharmD @theamirimani.bsky.social · 05/09/2026
TGFFS (Thank God For Follow-up Studies) High dose Vit D in metastatic colorectal cancer: - Lots of epi + phase 2 data suggesting benefit - Plausible-ish mechanism And when it was actually tested in a proper RCT? No benefit. 🅾️ And that's valuable info. #Medsky
jamanetwork.com
Addition of High-Dose Vitamin D3 to Standard Treatment for Metastatic Colorectal Cancer
This randomized clinical trial assesses whether high-dose vitamin D3, compared with standard-dose vitamin D3, added to standard chemotherapy improves progression-free survival in patients in the US Na...
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Amir, PharmD @theamirimani.bsky.social · 23/03/2026
"I spoke with a new nurse taking care of my dad today. Guess there's been a regime change at the hospital"
Excerpt:

Trump says US has had 'very intense discussions' with Iran.

CNBC news anchor Joe Kernen says he's just had a quick phone call with US President Donald Trump, who he reports says there have been "very intense discussions" with the Iranians.

Kernen asked who the US has been speaking to and was told by the president "well, they have representatives", he says.

In terms of the people in Iran involved in possible negotiations, Kernan says Trump tells him: "I consider this regime change, because these are new people that I'm talking to.
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Amir, PharmD @theamirimani.bsky.social · 28/02/2026
Sitting between an exhausting and heartbreaking past few months and an uncertain and likely volatile future. I'm still going to celebrate a monster's death.
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Julia Métraux @juliametraux.bsky.social · 21/02/2026
This was the offending article to save you a Google search (also there's no way I could have written this without someone getting mad at me, but wishing me death is extreme). www.motherjones.com/politics/202...
motherjones.com
Doctors Without Borders among dozens of aid groups Israel moves to shut down in Gaza
Allied nations condemned the decision, warning it could halt relief operations within weeks.
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Amir, PharmD @theamirimani.bsky.social · 11/02/2026
I maintain that pharmacy and medical students should be made to take an iron supplement twice daily and a calcium supplement three times daily just to see what that feels like. Unethical? Yes. Educational? YES. #RxSky #MedSky
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Amir, PharmD @theamirimani.bsky.social · 31/12/2025
I think the biggest misconception people have about preventative/full body imaging is that they think it'll speak for itself. Actual interpretation of everything from imaging the labs to even meds requires context: what is the problem? What are we trying to rule out? #MedSky #RxSky
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Amir, PharmD @theamirimani.bsky.social · 25/12/2025
Lead poisoning as treatment for joint pain? Don't let big government get in the way of This cutting-edge research. "Joint pain supplement recalled nationwide over lead concerns" thehill.com/homenews/566...
thehill.com
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Amir, PharmD @theamirimani.bsky.social · 10/12/2025
My house is old. But it's got good bones. Just not a great bladder.
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The Beaverton @thebeaverton.com · 07/12/2025
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The American Academy of Pediatrics @ameracadpeds.bsky.social · 05/12/2025
“This irresponsible and purposely misleading guidance will lead to more hepatitis B infections in infants and children.” Read our full statement by AAP President Dr. Susan J. Kressly: www.aap.org/en/news-room...
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Emily Moin @emilymoin.com · 19/11/2025
INCREDIBLE CURVES
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Eric Topol @erictopol.bsky.social · 18/11/2025
We've seen some remarkable outcomes in people with advanced, refractory cancers, including pancreatic, melanoma, and renal, with personalized neoantigen mRNA vaccines. But this work is now endangered. www.scientificamerican.com/article/pers...
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Paul Williams @paulnwilliams.bsky.social · 13/11/2025
He had a whatnow?
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Timothy Caulfield @caulfieldtim.bsky.social · 12/11/2025
Ottawa! Next week! 👇 This is a critical time. A knowledge crisis. How did we get here & what can we do? How to Escape the Fake: Making Good Policy in the Age of Misinformation : irpp.org/irpp-event/f... via @irpp.org @cmadocs.bsky.social Hope to see there!
irpp.org
How to Escape the Fake: Making Good Policy in the Age of Misinformation - IRPP
Join us for an evening of dialogue and networking with Canada’s dynamic public policy community.   This year’s IRPP fall lecture will feature Canadian author and scholar Timothy Caulfield, one of Nort...
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Amir, PharmD @theamirimani.bsky.social · 12/11/2025
How's the OB-GYN presence here #MedSky? Been thinking about about the tynelol/autism fiasco and interested in seeing how colleagues in those fields are doing
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Raywat Deonandan 🍁🇨🇦 @deonandan.bsky.social · 10/11/2025
Love it when the newspaper publishes a photo of me with the caption, "Embarrassing and sad."
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Amir, PharmD @theamirimani.bsky.social · 07/11/2025
I don't understand It's a natural supplement with a natural yellow dye. What do you mean it can - *checks notes* Cause convulsions, diarrhea, and coma? www.cspi.org/cspi-news/fd... #MedSky #RxSky
cspi.org
FDA update: These supplements contain toxic yellow oleander
Nov. 3, 2025: FDA completes list of tejocote root supplements that may contain toxic yellow oleander, which causes severe health risks and may be fatal.
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MedPage Today @medpagetoday.com · 20/10/2025
Fewer toddlers developed peanut allergies after guidelines recommended introducing peanut products in infancy, a large primary care registry study showed. 🥜⬇️
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Amir, PharmD @theamirimani.bsky.social · 21/10/2025
Happy to see the tradition of "robbing the Louvre in the most basic way possible" return.
Article on 2025 Louvre robbery stating thieves just drove a truck with a ladder up to the museum on a Sunday morning.Wikipedia article on the 1911 theft of the Mona Lisa stating the thief walked in one morning when the museum was closed the visitors, grabbed the painting when the room was empty, wrapped it in a shirt and left.
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Amir, PharmD @theamirimani.bsky.social · 17/10/2025
*Looking over at the US* "Damn that's fucked up" *Get email from Ontario grad student union* "Hey wait a minute"
Except from email regarding Ontario Bill 33:

WHAT IS BILL 33

Bill 33 is an omnibus bill currently at Second Reading that bundles unrelated reforms affecting child welfare, K-12 education, and post-secondary institutions. Schedule 3 of the bill targets colleges and universities through three dangerous provisions:

Fee Regulations (Section 21.1): Gives Cabinet authority over student union fees, threatening health/dental plans, food programs, legal support, and advocacy services

 Merit-Based Admissions (Section 16.0.2): Allows Cabinet to control university admissions criteria, risking equity programs and comprehensive assessment
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Amir, PharmD @theamirimani.bsky.social · 30/09/2025
One of the insidious problems with medical disinformation is that it "hogs the air". We spend time debunking BS and assuaging fears that we could have spent having actually valuable discussions. #MedSky #RxSky
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Amir, PharmD @theamirimani.bsky.social · 07/09/2025
There's another lesson in polio too. Humor me a bit: ❓What percentage of kids with polio actually went on to develope paralytic poliomyelitis? A) 5% B) 12% C) 0.5% D) 3%
Photo of an iron lung ward.
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Amir, PharmD @theamirimani.bsky.social · 24/07/2025
*Tiny soapbox* Calling it "Western Medicine" whitewashes historical and ongoing contributions made to modern medicine by the global community. It's meaningless and unnecessarily divisive. #RxSky #MedSky
The book spines for the Canon of Medicine.
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Amir, PharmD @theamirimani.bsky.social · 16/07/2025
In case there's interest: Here's a study on turmeric for OA that's got ok methodology (small though). I looked up the turmeric they used (full study paywalled) and it looks like a proprietary formulation with better absorption without black pepper. #Medsky www.acpjournals.org/doi/10.7326/...
acpjournals.org
Effectiveness of Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee Osteoarthritis: A Randomized Trial: Annals of Internal Medicine: Vol 173, No 11
Background: Current pharmacologic therapies for patients with osteoarthritis are suboptimal. Objective: To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–...
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Amir, PharmD @theamirimani.bsky.social · 15/07/2025
Here's a fun little fact about this story... #RxSky #MedSky www.independent.co.uk/news/world/a...
independent.co.uk
New Jersey woman nearly dies after taking dangerous amount of popular supplement
New Jersey resident Katie Mohan says her daily turmeric supplements gave her ‘impending liver failure’
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Dr. Jonathan N. Stea @jonathanstea.bsky.social · 11/07/2025
Confessions of a former naturopath.
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Amir, PharmD @theamirimani.bsky.social · 24/06/2025
My version of "don't make me tap the sign"
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Amir, PharmD @theamirimani.bsky.social · 18/06/2025
"That suppository made me bleed out the butt" "Oh that's terrible I'm sorry. Just to confirm: You took off the foil wrapping before inserting it, right?" "..."
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Mark A. Hanson @hansonmark.bsky.social · 10/06/2025
New from The Strain Team: 🎊 Springer Nature Discovers MDPI 🎊 Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗). Gross! 😀 1/n #ResearchIntegrity #SciPub #AcademicSky
the-strain-on-scientific-publishing.github.io
Spinger Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
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josh farkas 💊 @pulmcrit.bsky.social · 09/06/2025
The ideal cutoff for adequate time-to-antibiotic delivery in septic shock is being discussed again 🤦‍♂️ Should we be required to give antibiotics in 1 hr? 3 hr? 15 minutes? 3.14159 minutes? This is worth a short thread on the background of this topic Buckle up, it's a mess... #EMIMCC #IDsky #1/6
media.tenor.com
a man with a surprised look on his face and the words how did this happen below him
ALT: a man with a surprised look on his face and the words how did this happen below him
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Amir, PharmD @theamirimani.bsky.social · 08/06/2025
My favorite farsi insult: Namak-nashnaz Approximate translation: Ungrateful, unappreciative. Literal translation: One who does not recognize salt 🧂 Devastating in the culinary scene, I'm sure. You're welcome.
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Amir, PharmD @theamirimani.bsky.social · 04/06/2025
"These things are the ideal way to help people quit smoking!" ⬇️ "Ok there are apparently more kids who use vapes than would have every smoked cigarettes" ⬇️ "Researchers are looking at using smoking cessation drugs to help kids quit vaping" jamanetwork.com/journals/jam... Medsky / RxSky
jamanetwork.com
Varenicline for Youth Nicotine Vaping Cessation
This randomized clinical trial evaluates the efficacy of varenicline plus behavioral counseling, compared with placebo plus behavioral counseling or with enhanced usual care (behavioral counseling alo...
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Doctors Without Borders / Médecins Sans Frontières (MSF) @msf.ca · 02/06/2025
Following attacks on humanitarians in Gaza and Sudan, including on Doctors Without Borders staff, the silence is deafening. No outrage. No accountability. @chrislockyear.msf.org, our Secretary General, speaks of the cost for killing humanitarians. www.doctorswithoutborders.ca/what-is-the-...
doctorswithoutborders.ca
What is the cost for killing humanitarians? | Doctors Without Borders / Médecins Sans Frontières (MSF ...
By Christopher Lockyear, secretary general, MSF. Originally published on swissinfo on May 26, 2025.   On Saturday, May 3, we at Doctors Without Borders/Médecins Sans Frontières (MSF) woke to shock, gr...
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Amir, PharmD @theamirimani.bsky.social · 01/06/2025
Not to be mean but I can't even humour the usual "Why don't you move to the states? You'd make so much more money there!" conversations anymore.
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Amir, PharmD @theamirimani.bsky.social · 28/05/2025
If I can teach one thing to regular folks: Treat supplements with the same caution you treat prescription drugs. RxSky MedSky newzsquare.com/rates-of-liv...
newzsquare.com
Rates Of Liver Injuries Rise In The U.S. As Supplements Grow In Popularity
It started with nausea and loss of appetite.
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Amir, PharmD @theamirimani.bsky.social · 26/05/2025
Medsky / RxSky when folks are complaining about the "horrible gardening advice" going around on TikTok.
James Franco "First time?" meme
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Carl T. Bergstrom @carlbergstrom.com · 24/05/2025
2 At first glance, section 3 might look like a really good thing. A lot of these are pillars of the science reform movement. But we've already seen these principles used for the purpose of agnogenesis—creating doubt around scientific findings to stave off regulation or push a political agenda.
Sec. 3.  Restoring Gold Standard Science.  (a)  Within 30 days of the date of this order, the Director of the Office of Science and Technology Policy (OSTP Director) shall, in consultation with the heads of relevant agencies, issue guidance for agencies on implementation of “Gold Standard Science” in the conduct and management of their respective scientific activities.  For the purposes of this order, Gold Standard Science means science conducted in a manner that is:
(i)     reproducible;
(ii)    transparent;
(iii)   communicative of error and uncertainty;
(iv)    collaborative and interdisciplinary;
(v)     skeptical of its findings and assumptions;
(vi)    structured for falsifiability of hypotheses;
(vii)   subject to unbiased peer review;
(viii)  accepting of negative results as positive outcomes; and
(ix)    without conflicts of interest.
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Monica Verduzco-Gutierrez @mvgutierrezmd.bsky.social · 18/05/2025
I missed World hypertension day - which conveniently is in the middle of stroke awareness month. Here to remind you high blood pressure is the leading and most controllable risk factor for stroke. And for a given level of high blood pressure, the risk of stroke may be higher in women.
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Timothy Caulfield @caulfieldtim.bsky.social · 05/05/2025
The reviews are in, but can we trust them? [SPOILER: NO!] Why you should be skeptical of online reviews www.ctvnews.ca/edmonton/ctv... Fun chat on CTV Edmonton about fake & manipulated online reviews. Sum: It's a problem!
ctvnews.ca
The reviews are in, but can we trust them? Why you should be skeptical of online reviews
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Stacey D. Smith @iochromaland.bsky.social · 05/05/2025
On Friday, my son stayed home from school because he had a sore throat and wasn’t feeling well. He went with my husband to his office for the morning while I handled our daughter. When he came back at lunch, he was not interested in eating, saying his throat hurt too much. 1/n
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Amir, PharmD @theamirimani.bsky.social · 05/05/2025
Drug memes. #MedSky #RxSky
What is my purpose meme with clavulonite being told it's just a decoy.
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Amir, PharmD @theamirimani.bsky.social · 25/04/2025
A meta-analysis of 💩 is just more powerful 💩
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Paul Sax @paulsaxmd.bsky.social · 18/04/2025
The SNAP trial may finally resolve some of the longest-running debates in SAB management (cefazolin vs semi-synthetic PCN? Is PCN really active vs PSSA?). Huge congrats to Drs. Joshua Davis, Steven Tong, & the global team who made this ambitious trial happen. #IDSky blogs.jwatch.org/hiv-id-obser...
blogs.jwatch.org
SNAP Trial Helps Resolve Long-Running Controversies Over Management of Staph Bacteremia
For those who do hospital-based patient care, the significance of Staphylococcus aureus bacteremia (SAB) cannot be overstated. It’s one of the most frequent reasons for infectious disease consultation...
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Doctors Without Borders / Médecins Sans Frontières (MSF) @msf.ca · 16/04/2025
On March 28 and 29, settlers and Israeli forces stormed and attacked the Jinba community in #MasaferYatta, #WestBank, #Palestine. Five Palestinians were hospitalized —two in intensive care, including a child.
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Amir, PharmD @theamirimani.bsky.social · 11/04/2025
Unless someone's got multiple clinical trials to cite, I stand by this rule
A line graph with the heading "Supplements" and "Number of claimed benefits" on the x-axis and "Bullshit likelihood" on the y-axis. The line itself is climbing at a 45° angle.
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Amir, PharmD @theamirimani.bsky.social · 24/02/2025
Interesting to see so much news about measles outbreaks and hospitalization that doesn't even mention its effect on the immune system. It's not good guys #MedSky #PharmSky www.bbc.com/future/artic...
bbc.com
Measles: The race to understand 'immune amnesia'
Scientists have known for years that measles can alter the immune system – but the latest evidence suggests it's less of a mild tweaking, and more of a total reset.
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Amir, PharmD @theamirimani.bsky.social · 11/04/2025
Really great 🧵 by someone I'm excited to see on BlueSky
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Amir, PharmD @theamirimani.bsky.social · 06/04/2025
Alright hear me out: Laugh tracks in Academic Presentations. Cued by presenter in case their jokes don't land. Great idea or amazing idea? #Medsky #RxSky
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Amir, PharmD @theamirimani.bsky.social · 02/04/2025
"Severe osteopenia" is weird, right? Like it's not a helpful descriptor, especially in asymptomatic adults? Are we also telling people they have severe subclinical hypothyroidism? Am I being silly #Medsky?
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