Reposted by @taseef.bsky.socialKaia Mattioli @kaiamattioli.bsky.social · 02/10/2025tepid take: a lotttttt of job postings for bio-AI researchers, not enough job postings for generating-the-extremely-necessary-data-for-bio-AI researchers 1277
Reposted by @taseef.bsky.socialDiego del Alamo @delalamo.xyz · 25/08/2025Can't find the words so heres a diagram, apologies for bad handwriting. Higher energy states that are in between the two conformations you care about are both more combinatorially plentiful, and rarer, and only a few of them matter. mAb CDRs can interconvert on 10s of µs so it matters for those too 142
Reposted by @taseef.bsky.socialSergey Kryazhimskiy @skryazhi.bsky.social · 12/08/2025I've not used AI as seriously as Will here, but my experience is similar. Introductory-level assistance is amazing! They always point you in the right direction if you have no clue how to approach a problem. But when expert knowledge is required, lots of serious mistakes, some obvious, others not. 182
Reposted by @taseef.bsky.socialGabriele Corso @gcorso.bsky.social · 06/06/2025Excited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀 1021391
Reposted by @taseef.bsky.socialDiego del Alamo @delalamo.xyz · 27/03/2025Reposting this probably-useful tool from LinkedIn that maps UniProt IDs to PDBs github.com/iriziotis/Un... 2266
Reposted by @taseef.bsky.socialPitágoras Alves @pitagoras-alves.bsky.social · 27/12/2024I decided to make the datasets I'm generating for my phd project public. For each protein in Swiss-Prot, I'm making available PLM embeddings (ProtTrans, Ankh, ESM2), GO annotations and taxonomy representations. All files follow the same order, one line per protein. github.com/pentalpha/pr...github.comGitHub - pentalpha/protein_dimension_db: Datasets with embeddings and other representations for all proteins in Uniprot/Swiss-ProtDatasets with embeddings and other representations for all proteins in Uniprot/Swiss-Prot - pentalpha/protein_dimension_db 22310
Reposted by @taseef.bsky.socialAnna Tanczos @scicommstudios.bsky.social · 28/11/2024Beta-lactoglobulin having a little wiggle. The main whey protein in the milk of many mammals (except humans). Seen here traversing various configurations determined using NMR (1dv9.pdb). Imagine it dancing to music of your choice😂. 🧪⚗️ 🧶🧬🐡 #c4d #CompChemSky #SciComm 07618
Reposted by @taseef.bsky.social🌞 𝐋𝐨𝐚𝐢𝐳𝐚 @academicaries.bsky.social · 21/11/2024turning assignments in early >>> 101288
