Sign in

Sakari Vanharanta

@svanharanta.bsky.social
375 followers 541 following 13 posts

Sigrid Jusélius Professor, Translational Cancer Medicine Program & Department of Biochemistry and Developmental Biology, University of Helsinki, Finland. #cancer #genomics #transcription #chromatin

PostsRepliesMedia
Sakari Vanharanta @svanharanta.bsky.social · 14/04/2025
New issue of Annual Reviews of Cancer Biology is out! www.annualreviews.org/content/jour...
annualreviews.org
Annual Review of Cancer Biology | Annual Reviews
AIMS AND SCOPE OF JOURNAL: The Annual Review of Cancer Biology reviews a range of subjects in cancer research that represent important and emerging areas in the field. With recent advances in our unde...
010
Sakari Vanharanta @svanharanta.bsky.social · 21/03/2025
www.cnbc.com/2025/03/19/w...
cnbc.com
Finland is the happiest country in the world for the eighth year in a row
For the eighth year in a row, Finland ranked in the top spot on the World's Happiness Report's annual ranking of the happiest countries in the world.
040
Sakari Vanharanta @svanharanta.bsky.social · 16/01/2025
Very interesting work on the role of germline genetics in somatic tumor evolution.
131
Sakari Vanharanta @svanharanta.bsky.social · 07/01/2025
Last few days to apply👇! In addition to hot science, our campus offers refreshing dips within walking distance 💪🏖️ #BalticSea #Helsinki
Laajalahti Bay in JanuaryLaajalahti Bay in January
031
Reposted by Sakari Vanharanta
Adaptmet @adaptmet.bsky.social · 20/12/2024
Looking for a PhD? Follow this🧵 to know how Adaptmet's innovative training will combine continuous training in cutting-edge metastasis research with custom-made network-wide events to enhance, accelerate & elevate the skills, capacities & network of our doctoral candidates (DCs)
153
Reposted by Sakari Vanharanta
AndreaVentura @andreaventura.bsky.social · 18/12/2024
🧪1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! Let’s dive in! 🧵👇 www.nature.com/articles/s41...
nature.com
Engineered extrachromosomal oncogene amplifications promote tumorigenesis - Nature
Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role of oncogene a...
1111842
Reposted by Sakari Vanharanta
Ulrich Elling @ulielling.bsky.social · 16/12/2024
Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology. 1/ www.nature.com/articles/s41...
nature.com
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology
Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.
24717
Sakari Vanharanta @svanharanta.bsky.social · 16/12/2024
aacrjournals.org/cdnews/news/...
aacrjournals.org
Inherited Gene Variant Tied to Breast Cancer Spread
A common germline variant of PCSK9 significantly increases the risk of breast cancer metastasis, a new study has revealed. The finding—a first example of inherited genes driving metastatic progression...
000
Sakari Vanharanta @svanharanta.bsky.social · 10/12/2024
Come join us!
022
Sakari Vanharanta @svanharanta.bsky.social · 10/12/2024
Very interesting insight into tumor-immune interaction under chemotherapy in ovarian cancer. Congrats Anniina, Anna and the teams!
040
Reposted by Sakari Vanharanta
Memorial Sloan Kettering Cancer Center @mskcancercenter.bsky.social · 04/12/2024
New in @natureportfolio.bsky.social from the Tuomas Tammela Lab: how aging suppresses tumorigenesis and stemness in the lung by promoting functional iron insufficiency in the alveolar epithelium. Interestingly, this renders aged cells resistant to ferroptosis. #OncSky www.nature.com/articles/s41...
nature.com
Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature
Studies using mouse models of lung adenocarcinoma identify an association between age, iron homeostasis and tumour initiation potential that involves NUPR1 and lipocalin-2.
1207
Reposted by Sakari Vanharanta
Kristian Pietras lab @kpietraslab.bsky.social · 04/12/2024
Come join us and @svanharanta.bsky.social @cedric-blanpain.bsky.social Roger Gomis @irbbarcelona.bsky.social @obenaufa.bsky.social Karin de Visser @nkinl.bsky.social @grauperalab.bsky.social @prat-aleix-md.bsky.social @vickysanzmoreno.bsky.social @johannajoyce.bsky.social @momobentires.bsky.social
1127
Sakari Vanharanta @svanharanta.bsky.social · 27/11/2024
Inflammatory monocytes can restimulate T cells in tumors, and cancer cell-induced disruption of this process can lead to tumor immune evasion. Details 👇 in the wonderful 🧵 by @obenaufa.bsky.social and the paper published today @Nature. What a privilege it has been to be part of this amazing team!
031
Sakari Vanharanta @svanharanta.bsky.social · 25/11/2024
Hello Bluesky, we are recruiting PhD students in cancer and metastasis biology! This is a fantastic program that brings together several leading European research institutes. Details here: adaptmet.eu/recruitment/
adaptmet.eu
Recruitment
Recruitment is now open! Apply for one of the 16 positions availablein the Adaptmet network and build your futureas a researcher in metastasis! Adaptmet is offering generous three-year fellowship...
02516