I believe that water is a human right and I don’t want it to fall through the cracks. I’ve signed this petition to demand the UK government champions water for regions affected by conflict and climate...

Antiphospholipid syndrome (APS) is characterised by thrombosis and/or pregnancy morbidity associated with persistent antiphospholipid antibodies (aPL). Beyond the criteria antibodies, non-criteria aPL...

Protect people. Regulate powerful platforms. Keep the internet open. The Government is planning to introduce tough new laws that require all adults to show ID to access to go online. They say this is ...

Support for those struggling with water bills is unfair and inconsistent, forcing many people on low incomes people into impossible choices to make ends meet. That's why I've just signed Independent A...

Feeling the pinch? MPs have the power to ensure your food bill isn't one of the things keeping you up at night. Tell yours to support your right to food today.

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Millions of graduates are being ripped off by sky-high interest rates, with balances growing faster than they can be paid off! Add your name to demand fairer student loan terms in the upcoming Budget.

Suicide is the leading killer of young people in the UK. Every day, an estimated 300 to 450 young people aged 16 to 35 attempt suicide, with rates now at their highest level in 30 years (Office for Na...

Background, objective, and methods: Antiphospholipid syndrome (APS) is classically regarded as a cause of thrombosis and stroke in younger patients and is often considered a rare etiology beyond the s...

Millions of graduates are being ripped off by sky-high interest rates, with balances growing faster than they can be paid off! Add your name to demand fairer student loan terms in the upcoming Budget.

Adrenal involvement is a rare but potentially severe immunothrombotic manifestation of antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE)-spectrum disease. Because the term adrenal...

Your MP can be one of the MPs telling the Prime Minister that he has to deliver public ownership.

Are you on your phone? Scroll to sign the petition No jobs. No homes. No future. That’s what it can feel like for young people in the UK. One million young people are out of work or education - and ...

Dear supporter, World leaders are gathering at the 81st Session of the UNGA this week. On 18 September 2024, the UN overwhelmingly endorsed the ICJ ruling that Israel’s occupation is illegal and cons...

Demand that Ofwat says no to bill hikes. Let water companies go bust and bring them into public ownership for nothing.

Support for those struggling with water bills is unfair and inconsistent, forcing many people on low incomes people into impossible choices to make ends meet. That's why I've just signed Independent A...

I've just signed this open letter calling on the government to guarantee everyone in the country gets a fair share of the benefits of renewable energy. Join me!

How should we regulate AI? We must ban AI that risks human rights violations. These include uses that: Allegedly 'predict' crime, assess a person’s ‘risk’ of criminal behaviour, and capture sensitive ...

On 12 October, Parliament will debate the UK's future relationship with Europe, after a government petition got over 100,000 signatures. Will you write to your MP to ask them to attend the debate?

Coventry City Council should end its contract with Palantir and bring data and AI services back under public control. We are calling for transparency, meaningful consultation with residents and trade ...

Neonatal antiphospholipid syndrome (APS) is an exceptionally rare but clinically significant thrombotic disorder associated with antiphospholipid antibodies (aPL) in the neonatal period. Two principal pathogenic mechanisms have been proposed: passive transplacental transfer of maternal antiphospholi …

Antiphospholipid syndrome (APS) is a prothrombotic autoimmune disorder associated with venous thromboembolism (VTE) and chronic thromboembolic pulmonary hypertension (CTEPH). Current guidelines recommend APS screening in CTEPH patients. The exact prevalence of APS in both CTEPH and chronic thromboem …

We are calling on the Chancellor to use the Budget to improve Housing Benefits to help older renters afford the cost of essentials. Will you join me in writing to your MP?

We are calling on the Chancellor to use the Budget to improve Housing Benefits to help older renters afford the cost of essentials. Will you join me in writing to your MP?

Across the UK, supermarkets and manufacturers flood our shelves with unhealthy products, push promotions on unhealthy food, and make healthier options harder to find and more expensive. Meanwhile, foo...

Across the UK, supermarkets and manufacturers flood our shelves with unhealthy products, push promotions on unhealthy food, and make healthier options harder to find and more expensive. Meanwhile, foo...

Two planned data centres will emit more carbon than the entire UK operations of ExxonMobil. Both plan to build their own gas power stations. Tell Andy Burnham to rule it out

Watching Big Chicken: A Fast Food Conspiracy, I was shocked to see the damage the chicken industry is doing to rivers, communities and animals. And now I’ve learned the Government wants to expand Big ...

Most patients with cryptogenic stroke and weakly positive aPLs received antiplatelet agents. Patients with weakly positive aPLs had a lower incidence of recurrent stroke compared with patients with strongly positive aPLs, despite less intensive antithrombotic therapy.

Together, we can make sure no one - however rich or powerful they may be - is allowed to take us or our democracy for a ride.

In January 2026, Donald Trump bombed oil-rich Venezuela, killing over 100 people, and illegally kidnapping Venezuelan President Nicolás Maduro and First Lady Cilia Flores. They are now being held i...

Palantir’s contract with NHS England is up for renewal in February 2027, with discussions expected to begin this year. This is a critical moment for us to tell the new Health Secretary: No Palantir in...

Guidance for antiphospholipid antibody (aPL) testing after unprovoked venous thromboembolism (VTE) is inconsistent. Real-world data on the prevalence and outcomes of antiphospholipid syndrome (APS) in...

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British politics is awash with money from super rich donors. In 2023, two-thirds of all private donations came from just 19 people. These so-called ‘mega donors’ enjoy privileged access to political p...

The 2023 ACR/EULAR APS classification criteria exhibit consistently excellent specificity but reduced and phenotype-dependent sensitivity. These findings reinforce the intended role of the criteria for classification rather than clinical diagnosis and highlight important limitations in specific APS …

We're building a movement to call for access to mental health support that makes people feel seen and starts on the day they ask for help. Ask your MP to attend Mind’s ‘Open Doors’ report launch and s...

🫰The Clacton by-election cost us £250,000. 🏥This petition calls on Reform to donate that amount to the NHS. Add your name now if you agree👇

I've just signed my name calling for the government to investigate Brits who have returned from serving in the IDF - you should too!

Too many people miss out on the end of life care they need. Let's change things.

Antiphospholipid syndrome (APS) lacks disease-modifying targeted therapies, and its molecular heterogeneity remains poorly characterized. We employed an integrative systems pharmacology approach combining weighted gene co-expression network analysis (WGCNA), single-cell RNA sequencing, Connectivity …