iiinova — where your digital self keeps evolving

Struan Grant @struangrant.bsky.social · 07/10/2026

Preprint from graduate student, @maweidekamp.bsky.social - NOW SEEKING A POSTDOC ROLE! Co-mentored with @bvoight28.bsky.social. Single-cell eQTL mapping in human pancreas. New signals not seen in bulk studies. Cell types of action implicated. @chopresearch.bsky.social @penngenetics.bsky.social

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Struan Grant @struangrant.bsky.social · 21/09/2026

New preprint from team member Anthony Gacita (@agacita.bsky.social) reports the 'Genomic Analysis of Variants in Unresolved Rare Disease' (GAVURD) system, which uses trio WGS alignment data to short list putative pathogenic non-coding variants for a given proband. www.biorxiv.org/content/10.6...

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Struan Grant @struangrant.bsky.social · 11/09/2026

Fantastic night last night hosting, along with Tara Wenger, the first ever Scottish Cèilidh at @chopresearch.bsky.social to celebrate 20 years for myself, Hakon Hakonarson and Marni Falk in the Division of Genetic & Genomic Medicine. Slàinte!

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Struan Grant @struangrant.bsky.social · 31/07/2026

In @genomeresearch.bsky.social: @atothezphd.bsky.social "Cross-species variant-to-function analyses implicate MEIS1 in conferring sleep abnormalities and impaired cerebellar development". Co-led with Allan Pack @chopresearch.bsky.social @penngenetics.bsky.social genome.cshlp.org/content/earl...

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Struan Grant @struangrant.bsky.social · 05/07/2026

Had a fantastic 4th of July watching France beat Paraguay in Philadelphia!

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Struan Grant @struangrant.bsky.social · 30/06/2026

Congratulations to Dr. Max Dudek @maxdudek.bsky.social for being awarded his PhD yesterday!

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Struan Grant @struangrant.bsky.social · 20/06/2026

Great game today. Obviously not the result we wanted. Roll on Brazil! 🏴󠁧󠁢󠁳󠁣󠁴󠁿⚽️

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Struan Grant @struangrant.bsky.social · 26/04/2026

Great debate at the ECTS annual meeting @ectssociety.bsky.social . With Hanna Taipaleenmaki for the motion and Maria Ines Almeida against. Interestingly, lncRNAs won!

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Struan Grant @struangrant.bsky.social · 29/01/2026

A true honor speaking at the 'Festschrift' for my PhD supervisor from many years back. Best wishes to Stuart Ralston!

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Struan Grant @struangrant.bsky.social · 13/01/2026

Delighted to contribute to this work led by Kyla Mace and @kayserlab.bsky.social: "Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2". @penngenetics.bsky.social @chopresearch.bsky.social www.nature.com/articles/s41...

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Struan Grant @struangrant.bsky.social · 14/10/2025

Our #ASHG25 poster activities each day: 1097W Khanh Trang: Bone* 5071W Max Dudek: caQTLs 8042W Amber Zimmerman: Sleep 4083W Anthony Gacita: Pathogenic noncoding variants 9252T Mary Ann Weidekamp: Neuro & metab LDSC 5047T Ekta Singh: Ciliopathies 9206F Matthew Pahl: Glaucoma V2G* *Reviewers’ Choice

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Struan Grant @struangrant.bsky.social · 14/10/2025

Check out #ASHG25 Penn Genetics @penngenetics.bsky.social Booth #1319 Exhibit Level Halls A-B, Nonprofit and Advocacy Pavilion Tuesday, October 15 - Thursday, October 17

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Struan Grant @struangrant.bsky.social · 14/10/2025

Our #ASHG25 platform activities: Vrathasha Vrathasha: 3D genomics & glaucoma. 206AB, W 10.45-11 Winter Bruner: MPRA & childhood obesity. 205ABC, T 11-11.15 Matt Pahl: Ancillary Session, Predicted Effector Genes. 259A, F 1.45-1.15 Struan Grant chairs Metabolic Matrix session. 253ABC, S 10-11

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Struan Grant @struangrant.bsky.social · 22/05/2025

Go Spurs! Great to see them win a trophy after all the years of drought. I’m sure the press room will be busier than when I was there as a tourist 🤣

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Struan Grant @struangrant.bsky.social · 28/04/2025

Congratulations to Dr. Mitch Conery for winning this year's @upenngcb.bsky.social Saul Winegrad Award for Outstanding Dissertation! @bvoight28.bsky.social and I are the proud co-mentors. @penngenetics.bsky.social @chopresearch.bsky.social

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Struan Grant @struangrant.bsky.social · 16/01/2025

Khanh Trang in our @elife.bsky.social paper integrates 3D genomic maps for >50 diverse cell types with pediatric obesity GWAS. Findings implicate a role for pancreatic islet cell types. Our #V2G mapping nominates effector genes. @penngenetics.bsky.social doi.org/10.7554/eLif...

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Struan Grant @struangrant.bsky.social · 05/11/2024

Check out our lab #ASHG2024 #ASHG24 posters: 4120W Khanh B. Trang (substance use disorders #V2F) 5102T Mitchell Conery (BMD non-coding CRISPRi); co-mentor Benjamin Voight 6027F Mary Ann Weidekamp (pancreatic eQTLs); co-mentor Benjamin Voight 6076F Winter Bruner, PhD (childhood obesity MPRA)

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Struan Grant @struangrant.bsky.social · 29/09/2024

Another MS Society #citytoshore in the bag! It was a good cycle ride yesterday - but a bit tougher than usual given suboptimal weather

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Struan Grant @struangrant.bsky.social · 26/09/2024

From the @cambupenn.bsky.social thesis work of Sheridan Littleton, we share in #STARProtocols our methodology to study cis-regulatory activity of GWAS loci for specific gene promoters in human primary astrocytes using luciferase reporter assay. www.sciencedirect.com/science/arti...

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Struan Grant @struangrant.bsky.social · 24/09/2024

Congratulations to Dr Elizabeth Burton! PhD awarded today with @cambupenn.bsky.social. Good luck with next steps at The Broad Institute

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