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Jonathan Mitchell

@j-a-mitchell.bsky.social
119 followers 99 following 0 posts

Associate Professor of Pediatrics at UPenn and CHOP | wearables | data science | sleep | nutrition

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Reposted by Jonathan Mitchell
Struan Grant @struangrant.bsky.social · 24/03/2026
Delighted to contribute to this review of the genetics of obesity, just out in @natmetabolism.nature.com, led by Amélie Bonnefond and Philippe Froguel. @chopresearch.bsky.social @penngenetics.bsky.social www.nature.com/articles/s42...
nature.com
The genetics of obesity: aetiology, prevention and therapy - Nature Metabolism
This Review discusses the genetics of obesity, highlighting its diverse forms and describing technological advancements in genetic studies that may enable precision medicine strategies to combat obesi...
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Reposted by Jonathan Mitchell
Struan Grant @struangrant.bsky.social · 14/10/2025
Just out: Led by @j-a-mitchell.bsky.social and Babette Zemel "gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood" @asbmr.bsky.social. Funded by our #NICHD award R01 HD100406. @chopresearch.bsky.social @penngenetics.bsky.social academic.oup.com/jbmr/article...
academic.oup.com
The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood
Abstract. The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using machine learning algorithms in adults of Europ
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Reposted by Jonathan Mitchell
Juliette Brook @juliettebrook.bsky.social · 06/05/2025
Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯 Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
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Reposted by Jonathan Mitchell
Struan Grant @struangrant.bsky.social · 24/04/2025
PREPRINT: Led by @j-a-mitchell.bsky.social & Babette Zemel, we show higher gSOS polygenic score associated with higher pediatric aBMD 🦴 & lower fracture risk @chopresearch.bsky.social . gSOS previously developed with ML on adults by @brent-richards.bsky.social team www.medrxiv.org/content/10.1...
medrxiv.org
The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood
The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using machine learning algorithms in adults of European ancestry and associates with reduced odds of fractu...
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