Laminin N-terminus α31 (LaNt α31) is a netrin-like protein generated by alternative splicing of the laminin α3 gene. While previously shown to regulate vascular permeability in vivo, its role in epith...

Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and meta...

Vinculin buffers force via dynamic domain unfolding/refolding under physiological load and lacks a stable head-tail lock.

Cardiomyocytes’ sensing of extracellular matrix stiffness is imprinted in the talin interactome and regulates their phenotype.

Mechanotransduction is fundamental to cell signaling and depends on force-sensitive adhesion proteins. How these proteins differentiate and integrate their responses to tension remains an open questio...