Background and Aims A Study Within A Trial (SWAT) is a research study embedded within a larger trial which aims to investigate different strategies for a particular trial process, such as trial recrui...

Background Randomised controlled trials (RCTs) are the gold standard for evaluating treatment effects, with the results informing policy and clinical practice. To ensure appropriate methods are utilis...

Background Randomised controlled trials (RCTs) are the gold standard for evaluating treatment effects, with the results informing policy and clinical practice. To ensure appropriate methods are utilis...

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Join us for Professor Victoria Cornelius' inaugural lecture in person or online.

Background An estimand is a precise description of the treatment effect a trial is aiming to find out. We previously identified that public partners (defined as patients and/or members of the public w...

We have an iCASE studentship available to start for the 2025/2026 academic year, and applications to our fifth round of recruitment to our DTP to start in October 2026 are now also open. Please see…

This summer, I had the opportunity to attend the 46th Annual Conference of the International Society for Clinical Biostatistics (ISCB) in Basel. It was an incredible week of learning and networking wi...

Non-inferiority (NI) trials typically require larger sample sizes than superiority comparisons. This is problematic for uncommon conditions where recruitment is restricted. When a power calculation re...

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Background The use of estimands in clinical trials was formalised with the adoption of the final International Conference on Harmonisation E9 Addendum on Estimands and Sensitivity Analysis in Clinical...

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Therapeutic options for people experiencing neuropathic pain from diabetic peripheral neuropathy are limited, and impact can be severe. Physical and psychological interventions remain under-explore...

The community dedicated to leading and promoting the use of statistics within the healthcare industry for the benefit of patients.

Abstract. When it comes to highly technical statistical methodology research, is patient and public involvement and engagement relevant, or just a funding

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

The study aimed to assess the design, reporting, and risk of bias in effectiveness trials in manual therapy, comparing pragmatic with non-pragmatic trials and trials with and without placebo controls.

The PPI for Statisticians Community of Practice (CoP) aims to bring together statisticians who are interested in patient and public involvement to share experiences for others to learn from, share res...

Ruth Jack, Senior Research Fellow at University of Nottingham shares more about how members of the public were involved in her project 'Medication reviews and polypharmacy in primary care' funded by t...

To systematically investigate trustworthiness (methodological rigor, transparency, good governance, research integrity, and absence of misconduct) in randomized controlled trials (RCTs) of osteopathic...

When patients stop taking their assigned treatment in a clinical trial - whether due to side effects, lack of effectiveness, or personal choice - researchers often still want to understand how that tr...