iiinova — where your digital self keeps evolving

Reposted by Shubhankar Londhe

Pedro Beltrao @pedrobeltrao.bsky.social · 23/06/2026

Not being able to access the @ukbiobank.ac.uk is becoming a significant issue for a PhD student in our group and I can only imagine this is mirrored in many other places. It would be fantastic to at least have a timeline we could work with.

2125

Shubhankar Londhe @slondhe.bsky.social · 14/10/2025

Why be satisfied with coding variant gene impairments? Check out Eva’s poster to learn how we scale DeepRVAT to the WGS UKBiobank. It’s been great fun being a part of this project! #ASHG25

040

Shubhankar Londhe @slondhe.bsky.social · 14/10/2025

Excited to share UKBBGym at #ASHG25, a new benchmark for variant effect predictors using WGS, proteomics and phenotypes from 500K UKBiobank participants. Stop by for insights on the impact of non-coding variants and how computational scores stack up against exp assays. Poster 5022W, Wed 2:30-4:30.

083

Reposted by Shubhankar Londhe

Gagneur lab @gagneurlab.bsky.social · 09/09/2025

The Solvathons have been one of our most exciting research community experiences: Hands-on, effective – solving real cases during the events, and multidisciplinary – from clinicians to bioinformaticians. Thumbs up to the SolveRD community. Looking for more now with @erdera.bsky.social rdcu.be/eFaqO

rdcu.be

The Solve-RD Solvathons as a pan-European interdisciplinary collaboration to diagnose patients with rare disease

Nature Genetics - This Perspective presents the Solve-RD Solvathon model, an innovative, pan-European framework uniting clinical and bioinformatics experts to diagnose rare diseases through...

051

Reposted by Shubhankar Londhe

Samarendra Pani @samarendra-pani.bsky.social · 24/07/2025

[1/8] *New Open-Access Long Read Resource*. We sequenced 1,019 genomes from the 1000 Genomes Project sample cohort using @nanoporetech.com long-read sequencing (LRS) to median 17x coverage. Publication at go.nature.com/4ffPb8f. @hhu.de @crg.eu @embl.org @impvienna.bsky.social

14221

Reposted by Shubhankar Londhe

Stegle Lab @steglelab.bsky.social · 19/07/2025

@thbec.bsky.social is going to share preliminary results on Meta-DeepRVAT, a new approach for deep learning based meta-analysis improving the power of rare variant association studies using population scale external control cohorts. #MLCSB 📅 July 21 |📍 Poster A-312

144

Reposted by Shubhankar Londhe

Kipoi @kipoizoo.bsky.social · 28/05/2025

Join us for our next Kipoi Seminar with Katherine Pollard, Gladstone Institute of Data Science & Biotechnology,UCSF, Biohub @gladstoneinst.bsky.social @czbiohub.bsky.social 👉Human variant interpretation with sequence-to-activity models 📅Wed June 4,5:30pm CET🧬 kipoi.org/seminar/🦋@kipoizoo.bsky.social

kipoi.org

044

Shubhankar Londhe @slondhe.bsky.social · 25/05/2025

Excited to present at #eshg2025. Catch my talk on improving rare variant association studies using functional gene embeddings, on Monday at 11:45am (C26.06).

020

Reposted by Shubhankar Londhe

Eva Holtkamp @evaholtkamp.bsky.social · 25/05/2025

Excited to be back at #eshg2025! Come by my poster today to check out fresh results on how rare high impact variants influence gene expression across immune cells—analyzed in 5,000 UK Biobank participants

0103

Reposted by Shubhankar Londhe

Gagneur lab @gagneurlab.bsky.social · 06/03/2025

Tomorrow Johannes Hingerl @johahi.bsky.social gives a talk on scooby at #probgen25. Enjoy learning in the legendary CSHL auditorium how to model RNA-seq and ATAC-seq profiles in individual cells from half a megabase of genomic sequence. Preprint: doi.org/10.1101/2024...

0113

Reposted by Shubhankar Londhe

Kipoi @kipoizoo.bsky.social · 03/02/2025

Join us for our next Kipoi Seminar with with Pedro Tomaz da Silva @pedrotomazdasilva.bsky.social @gagneurlab.bsky.social @TU_Muenchen! 👉Nucleotide dependency analysis of DNA language models reveals genomic functional elements 📅Wed Feb 5, 5:30pm CET 🧬https://kipoi.org/seminar/ 🦋kipoizoo.bsky

0106

Reposted by Shubhankar Londhe

Gagneur lab @gagneurlab.bsky.social · 23/12/2024

Hey reg genomics folks, here is our little x-mas present: Flashzoi. Borzoi. Just as good. 3x faster. Thumbs up to @johahi.bsky.social for the great initiative, conception & implementation. Big thanks to Johannes Linder, David Kelley and colleagues to have created Borzoi and shared it freely.

0187