A new review finds that while humor builds resilience during remission, using comedy during acute depression can trigger intense anxiety and gelotophobia (fear of being laughed at).

Scientists have identified two specific types of brain cells that behave differently in people with depression, offering a clearer picture of what is happening inside the brain. By analyzing donated brain tissue with advanced genetic tools, the researchers found changes in neurons linked to mood and stress, as well as in immune-related microglia cells. These differences point to disruptions in key brain systems and reinforce that depression is rooted in biology, not just emotions.

We asked experts for advice on how to best support your kids as they navigate back-to-school season.

Negative thoughts are common. What matters is whether we can update them. New research shows how emotions and rumination can make negative interpretations stick.

A recent study suggests that basil extract might help ease anxiety and depression. When taken with standard antidepressants, patients using a nightly basil syrup reported greater symptom relief than those taking a placebo.

Transformation may be possible using an automated device.