LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 20/05/20263 great days at the SIC Summer School in Hornbæk with inspiring talks, short talks from young researchers, poster sessions, networking, and a trip to Esrum Abbey. Thank you to all speakers, participants, organisers, and the LEO Foundation for supporting the summer school. See you 24–26 May 2027. 022
Reposted by LEO Foundation Skin Immunology Research Center (SIC)niels-odum.bsky.social @niels-odum.bsky.social · 01/05/2026Elimination of cancer T cells with little collateral damage to healthy T cells by TCRVβ-ADC Congratulations to Chella K Vadivel at the LEO Foundation Skin Immunology Research Center (SIC) and co-authors with this new treatment strategy published in Blood Adv 👌👏💪🎊🎉🎼 lnkd.in/e4mWCpUTlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 022
Reposted by LEO Foundation Skin Immunology Research Center (SIC)Terkild Brink Buus @terkild.bsky.social · 17/04/2026This work was spearheaded by Maria Gluud and the team at Skin Inflammation & Cancer @niels-odum.bsky.social at @sic-ucph.bsky.social and our fantastic collaborators! Finally, this study would not have been possible without the support from LEO Foundation, DFF, @cancer.dk @novo-nordisk.bsky.social 031
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 17/04/2026SIC’s annual activity report for 2025 is now available online. Read latest updates from the Center here: sic.ku.dk/news/2026/an...sic.ku.dkSIC's Annual Activity Report 2025 010
Reposted by LEO Foundation Skin Immunology Research Center (SIC)gyrd-lab.bsky.social @gyrd-lab.bsky.social · 03/04/2026I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology. #TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance @sic-ucph.bsky.social @ludwigcancer.bsky.social doi.org/10.1126/scii...doi.orgUpstream ORFs control TNFR1 abundance and tissue tolerance to TNFUpstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF. 053
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026SIC researchers have delved deeply into fibroblasts of the intestines. They describe how these cells organise our immune responses in structures called ‘gut associated lymphoid tissues’. @ursmoerbe.bsky.social sic.ku.dk/news/2026/fi...sic.ku.dkFibroblasts: Organizers of the intestinal immune systemIntestinal immune responses must be carefully balanced, as disruptions can lead to conditions such as inflammatory bowel disease. A new study sheds light on how immune cells are organized in the human... 011
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026SIC researchers have found that Staph aureus on the skin releases toxins that activate both normal and cancerous T cells, leading to destruction of the skin barrier. Treatment with a new drug candidate, endolysins, can remove the bacteria and restore skin barrier function. sic.ku.dk/news/2026/st...sic.ku.dkStaphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell LymphomaResearchers from the LEO Foundation Skin Immunology Research Center (SIC) have made new insights into how Staphylococcus aureus augments skin barrier damage in Cutaneous T cell lym... 011
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026Researchers at SIC recently characterised the diversity of phagocytes in the intestine of healthy people and in those with inflammatory bowel disease. They describe precursor phagocyte populations and the emergence of activated dendritic cells in IBD. sic.ku.dk/news/2026/di...sic.ku.dkDiversity of mononuclear phagocyte populations in the healthy and inflamed human intestineResearchers from the LEO Foundation Skin Immunology Research Center (SIC) at the University of Copenhagen have made new insights into the composition of antigen presenting cells in the intestines of p... 011
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 18/12/2025Researchers at SIC have analysed the skin’s response to exposure to the contact allergen, nickel. They found that the response became more severe with repeated exposures and was likely due to a strong skin-resident T cell response to nickel. academic.oup.com/bjd/advance-...academic.oup.comHeterogeneous generation and expansion of epidermal-resident memory T cells in individuals allergic to nickelRepeated nickel exposure in individuals allergic to the metal leads to increased clinical reactions. The clinical reactions correlate with an accumulation 011
LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 09/12/2025📣 SIC Summer School 2026 — applications open! 📍Hornbæk, DK | 18–20 May 2026 🎯Theme: Skin Immunity & Homeostasis 💵Free (stay + meals). For PhD students & postdocs. ✍️Deadline: 15 Jan 2026 (23:59 CET). 🔗Full details: sic.ku.dk/summerschool/ 🔗Register here: eventsignup.ku.dk/sicss2026 1113