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LEO Foundation Skin Immunology Research Center (SIC)

@sic-ucph.bsky.social
76 followers 83 following 7 posts

The LEO Foundation Skin Immunology Research Center (SIC) paves the way to a better understanding and treatment of the skin diseases that plague a quarter of the world's population.

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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 20/05/2026
3 great days at the SIC Summer School in Hornbæk with inspiring talks, short talks from young researchers, poster sessions, networking, and a trip to Esrum Abbey. Thank you to all speakers, participants, organisers, and the LEO Foundation for supporting the summer school. See you 24–26 May 2027.
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Reposted by LEO Foundation Skin Immunology Research Center (SIC)
niels-odum.bsky.social @niels-odum.bsky.social · 01/05/2026
Elimination of cancer T cells with little collateral damage to healthy T cells by TCRVβ-ADC Congratulations to Chella K Vadivel at the LEO Foundation Skin Immunology Research Center (SIC) and co-authors with this new treatment strategy published in Blood Adv 👌👏💪🎊🎉🎼 lnkd.in/e4mWCpUT
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Reposted by LEO Foundation Skin Immunology Research Center (SIC)
Terkild Brink Buus @terkild.bsky.social · 17/04/2026
This work was spearheaded by Maria Gluud and the team at Skin Inflammation & Cancer @niels-odum.bsky.social at @sic-ucph.bsky.social and our fantastic collaborators! Finally, this study would not have been possible without the support from LEO Foundation, DFF, @cancer.dk @novo-nordisk.bsky.social
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 17/04/2026
SIC’s annual activity report for 2025 is now available online. Read latest updates from the Center here: sic.ku.dk/news/2026/an...
sic.ku.dk
SIC's Annual Activity Report 2025
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Reposted by LEO Foundation Skin Immunology Research Center (SIC)
gyrd-lab.bsky.social @gyrd-lab.bsky.social · 03/04/2026
I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology. #TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance @sic-ucph.bsky.social @ludwigcancer.bsky.social doi.org/10.1126/scii...
doi.org
Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF
Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF.
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026
SIC researchers have delved deeply into fibroblasts of the intestines. They describe how these cells organise our immune responses in structures called ‘gut associated lymphoid tissues’. @ursmoerbe.bsky.social sic.ku.dk/news/2026/fi...
sic.ku.dk
Fibroblasts: Organizers of the intestinal immune system
Intestinal immune responses must be carefully balanced, as disruptions can lead to conditions such as inflammatory bowel disease. A new study sheds light on how immune cells are organized in the human...
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026
SIC researchers have found that Staph aureus on the skin releases toxins that activate both normal and cancerous T cells, leading to destruction of the skin barrier. Treatment with a new drug candidate, endolysins, can remove the bacteria and restore skin barrier function. sic.ku.dk/news/2026/st...
sic.ku.dk
Staphylococcus aureus Augments Epithelial Skin Barrier Damage Through T Cell Activation in Cutaneous T Cell Lymphoma
Researchers from the LEO Foundation Skin Immunology Research Center (SIC) have made new insights into how Staphylococcus aureus augments skin barrier damage in Cutaneous T cell lym...
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 02/04/2026
Researchers at SIC recently characterised the diversity of phagocytes in the intestine of healthy people and in those with inflammatory bowel disease. They describe precursor phagocyte populations and the emergence of activated dendritic cells in IBD. sic.ku.dk/news/2026/di...
sic.ku.dk
Diversity of mononuclear phagocyte populations in the healthy and inflamed human intestine
Researchers from the LEO Foundation Skin Immunology Research Center (SIC) at the University of Copenhagen have made new insights into the composition of antigen presenting cells in the intestines of p...
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 18/12/2025
Researchers at SIC have analysed the skin’s response to exposure to the contact allergen, nickel. They found that the response became more severe with repeated exposures and was likely due to a strong skin-resident T cell response to nickel. academic.oup.com/bjd/advance-...
academic.oup.com
Heterogeneous generation and expansion of epidermal-resident memory T cells in individuals allergic to nickel
Repeated nickel exposure in individuals allergic to the metal leads to increased clinical reactions. The clinical reactions correlate with an accumulation
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LEO Foundation Skin Immunology Research Center (SIC) @sic-ucph.bsky.social · 09/12/2025
📣 SIC Summer School 2026 — applications open! 📍Hornbæk, DK | 18–20 May 2026 🎯Theme: Skin Immunity & Homeostasis 💵Free (stay + meals). For PhD students & postdocs. ✍️Deadline: 15 Jan 2026 (23:59 CET). 🔗Full details: sic.ku.dk/summerschool/ 🔗Register here: eventsignup.ku.dk/sicss2026
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