Quantile aggregation may lead to overstated claims about amyloid-cognition relationships

This study evaluates the quantile-aggregation method using both simulated data and publicly available Alzheimer disease randomized trial data.

This study evaluates the quantile-aggregation method using both simulated data and publicly available Alzheimer disease randomized trial data.

<em>Alzheimer's & Dementia: Translational Research & Clinical Interventions</em> journal bridges drug discovery research and clinical studies for dementia & Alzheimer's.

Background Amyloid removal has been used as a surrogate outcome in Alzheimer’s disease trials, allowing accelerated approval of aducanumab and lecanemab. The A4 (Alzheimer’s Clinical Trial Consortium ...

Background: Amyloid removal has been used as a surrogate outcome in Alzheimer's disease trials, allowing accelerated approval of aducanumab and lecanemab. The A4 (Alzheimer's Clinical Trial Consortium...

Federal officials said Harvard must enact “merit-based reform” in hiring and admissions and report international students who broke rules, among other steps. Harvard called the demands unlawful.

The administration has now targeted five schools’ federal funding as part of a pledge to combat what it considers to be antisemitism on university campuses.