iiinova — where your digital self keeps evolving

Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 05/09/2026

Anyone got ScienceCast to work with bioRxiv preprint? The summary remains blank and trying to get it done manually only generates error!

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

Ectopic expression in the eye reduces the amount of aggregates but EDTP overexpression in muscles has no detectable effect on the accumulation or toxicity of two different kinds of polyglutamine aggregates.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

EDTP is required during both development and adulthood to support normal fertility, with expression restricted to either stage alone being insufficient.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

The structure of the muscle, myofibril, and sarcomere appears normal in homozygous DJ694. DJ694 females have morphologically normal ovaries, implicating a functional rather than structural impairment.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

The fertilityand longevity phenotypes are recessive and can be fully rescued by three independent UAS-EDTP insertions. Expression of UAS-EDTP into animals with wildtype phenotypes does not affect female fertility or lifespan.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

EDTP transcript levels are reduced in DJ694, and homozygous flies exhibit reduced reproduction and shortened lifespan in both sexes.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 04/09/2026

Genetic characterization of DJ694, a viable GAL4 enhancer-trap allele of the age-regulated gene EDTP: www.biorxiv.org/content/10.6...

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 08/01/2026

On se resemble beaucoup a part pour le sport.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 28/11/2025

Unable to access Blast. Who and how do we contact you?

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 23/07/2025

The role of microtubules during muscle development: www.cell.com/developmenta... Check out the precise timing beautifully demonstrated with shine-GAL4 by @frankschnorrer.bsky.social lab Congrats to all authors involved.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 26/06/2025

Just found out that we lost Serge Fiori, another gem of Canadian music: ici.radio-canada.ca/nouvelle/217... Harmonium playing right now!

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 20/06/2025

Running for 333 days, 2 hours, 9 minutes OS X 10.11.6, Server 5.2

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 13/12/2024

7/20. 😭 the more energy and time I put in, the worth it gets.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 08/12/2024

Seymour made me realize that the most important is biology (phenotype) not fancy technologies that can often fool us.

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 02/12/2024

Our family is very sad today...Shmi passed away 😭

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Laurent Seroude 🪰🇨🇦🇫🇷 @seroude.bsky.social · 30/11/2024

17yrs ago since we lost Seymour Benzer. Here in the coffee room during a visit in 2005. "A Tribute to Seymour Benzer, 1921–2007":https://pmc.ncbi.nlm.nih.gov/articles/PMC2581933/

Benzer lab coffee room
Julien Muffat, Seymour Benzer, Stephanie Cornelison, Laurent Seroude, Bill Ja, David Walker sitting clockwise around a metal table.

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