As an undergrad, I started playing with what many of us call “miniature lungs in a dish.”
The work evolved and is now out as a manuscript in @cp-iscience.bsky.social
The question: How does starting cellular milieu shape regeneration?
www.cell.com/iscience/ful...
cell.com
Pulmonary Organoid Models Demonstrate Compositionally Driven Epithelial Plasticity and Immune Polarization
Aberrant epithelial regeneration and immune remodeling are hallmarks of chronic lung
diseases such as idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease.
How cellular context shap...