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Erin McAuley

@science-goblin.bsky.social
17 followers 28 following 22 posts

I love my dogs and I like watching htop go green. Staff Bioinformatics Scientist @fulcrumgenomics.com.

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Erin McAuley @science-goblin.bsky.social · 30/09/2026
I saw "grant-maxxing" on LinkedIn this morning and I just want to proactively announce my boycott of adding "-maxxing" to a bunch of pre-existing words that were perfectly fine on their own. No thank you, internet!
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Erin McAuley @science-goblin.bsky.social · 29/09/2026
>Predatory online behavioral advertising isn’t new, but companies’ use of AI to process data and target customers has magnified its harms www.eff.org/deeplinks/20...
eff.org
DraftKings Is Using AI to Supercharge the Harms of Online Behavioral Advertising
Online sports betting company DraftKings is using AI to target customers who are most likely to place losing bets and respond to gambling promotions. This kind of targeting is a form of online behavio...
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Erin McAuley @science-goblin.bsky.social · 25/09/2026
This is a comprehensive and fairly recent review of some tools for tumor neoantigen prediction: academic.oup.com/bib/article/...
academic.oup.com
Computational methods and data resources for predicting tumor neoantigens
Abstract. Neoantigens are tumor-specific antigens presented exclusively by cancer cells. These antigens are recognized as nonself by the host immune system
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Erin McAuley @science-goblin.bsky.social · 22/09/2026
ah yes, the time of year when I switch from my Mets baseball cap to my Mets beanie
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Erin McAuley @science-goblin.bsky.social · 09/09/2026
Want to catch up on recent base editing technology developments? Here you go: www.cell.com/cell-genomic...
cell.com
Base editing for precision therapeutics
Regmi et al. chart recent advances in DNA, RNA, and mitochondrial base editing for precision therapeutics. They discuss editor design, targetability, efficiency, off-target assessment, delivery strate...
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Erin McAuley @science-goblin.bsky.social · 25/08/2026
A $2.75 "convenience fee" to pay my utility bill online? Absolutely not. You can have my ACH transfer information or I will mail you a check like the elder millennial that I am.
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Erin McAuley @science-goblin.bsky.social · 24/08/2026
Some of the best scientific software is safe: predictable outputs, clear failures, useful tests, readable code. Working on the latest pixy update reinforced why that matters when working on scientific software. I wrote about what we learned: blog.fulcrumgenomics.com/p/how-to-wri...
blog.fulcrumgenomics.com
How to write safe software for science
By Erin McAuley
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Erin McAuley @science-goblin.bsky.social · 24/08/2026
What do you mean Closing Time by Semisonic is 28 years old?!
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Erin McAuley @science-goblin.bsky.social · 21/08/2026
team public health forever
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Erin McAuley @science-goblin.bsky.social · 19/08/2026
> You didn’t read the thing when you generated it, I won’t read it when I’m reading it.
vickiboykis.com
Write for people
Make it shorter.
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Erin McAuley @science-goblin.bsky.social · 19/08/2026
this is awesome
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Erin McAuley @science-goblin.bsky.social · 19/08/2026
"that un-fucks this PR" uhhh Claude, where did you learn that vocabulary
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Erin McAuley @science-goblin.bsky.social · 19/08/2026
There's Upper Wacker, Lower Wacker, and Lowest Wacker. This is a true fact about Chicago.
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Erin McAuley @science-goblin.bsky.social · 15/08/2026
According to Cardi B et al., 2026, "you can't flex on me with something I had". And what I had is a rudimentary understanding of Rust data structures. Now I have a _moderate_ understanding of Rust data structures.
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Erin McAuley @science-goblin.bsky.social · 07/08/2026
I am on my Rust learning journey. First things first, Ferris the crab is a pierogi in disguise.
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Reposted by Erin McAuley
Kieran Samuk @ksamuk.bsky.social · 03/08/2026
Just posted: a group paper describing major updates to my software pixy, for population genetic summary statistics. www.biorxiv.org/content/10.6... New since 2021: arbitrary ploidy, multiallelic sites, missingness-aware Watterson's θ and Tajima's D, Hudson's FST, multicore execution!
Alt text: Schematic of the pixy workflow. Left, inputs: a bgzipped, tabix- or CSI-indexed VCF with callable sites supplied as an all-sites VCF or gVCF blocks, a populations file, and optional BED and sites files. Centre, core: windowing by fixed width, BED or region; statistic selection; options for Hudson's FST, multiallelic SNPs, automatic ploidy detection and multicore execution. Right, outputs: one TSV per statistic for pi, dxy, FST, Watterson's theta and Tajima's D, with raw count columns for exact aggregation. Bottom, development: GitHub fork and pull request, local checks with ruff, mypy and pytest, continuous integration across Python 3.10 to 3.14, and distribution through conda-forge. Features new since the 2021 release are badged "new".
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Erin McAuley @science-goblin.bsky.social · 13/07/2026
things my berner dislikes: -heat -when he's not getting enough attention things my staffy dislikes: -large umbrellas and hats -sharing a blanket -small engine motors -bicycles -inclement weather -fast moving vehicles -potential murderers -cucumbers
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Reposted by Erin McAuley
Fulcrum Genomics @fulcrumgenomics.com · 17/06/2026
Full blog post: blog.fulcrumgenomics.com/p/bioinforma...
blog.fulcrumgenomics.com
Bioinformatics Still (Mostly) Runs on Old Plumbing
Some of the most valuable work happens in the tools underneath the tools
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Reposted by Erin McAuley
Heng Li @lh3lh3.bsky.social · 16/06/2026
Minibwa is a hybrid of bwa-mem and minimap2 and the successor of bwa-mem for short-read mapping. ~4X/2.5X as fast as bwa-mem/bwa-mem2 for WGS reads at comparable accuracy. Native support of directional bisulfite-seq. Applicable to long reads. Preprint at arxiv.org/abs/2606.15357
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Erin McAuley @science-goblin.bsky.social · 17/06/2026
tough year to be a Mets fan
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Erin McAuley @science-goblin.bsky.social · 12/06/2026
Here's how you say cell nucleus in Polish: jądro komórkowe ("YOHN-dro koh-moor-KOH-veh")
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Erin McAuley @science-goblin.bsky.social · 11/06/2026
What a beautiful take from @hankgreen.bsky.social in his latest video. You are a junk drawer, and your brain cannot tell you which egg becomes the fish.
youtube.com
No Effort is Wasted
YouTube video by Hank Green
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Erin McAuley @science-goblin.bsky.social · 08/06/2026
"Got the morbs" is Victorian slang for temporary melancholy. It's also the name of a band from Lincoln, Nebraska. So if you've got Monday morbs, maybe listen to their single, "Plague".
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