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Anton Calabrese

@antoncalabrese.bsky.social
235 followers 388 following 6 posts

Structural Proteomics | Dog owner | Amateur gardener | (He/him) 🇦🇺👨🏼‍🔬🔬☕️🍺✈️🐶 www.calabreselab.com

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Reposted by Anton Calabrese
Janet Kumita @jrkumita.bsky.social · 21/08/2026
Our UK Biomolecular Condensate monthly on-line seminars are back!! (4th Sept 2026, 1 pm BST) and all are welcome to come and listen. Martin Howard and Anton Calabrese are presenting! @antoncalabrese.bsky.social #condensates @physicsoflifeuk.bsky.social
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Reposted by Anton Calabrese
RadfordLab @radford-lab.bsky.social · 04/10/2025
See our latest paper on BAM action. Great work to the team and super collaborations with @naranson.bsky.social @antoncalabrese.bsky.social and @Jean Francois collet. Have a read rdcu.be/eJjDp
rdcu.be
Molecular insights into how the motions of the β-barrel and POTRA domains of BamA are coupled for efficient function
Nature Communications - BamA is the catalytic core of the BAM complex, which inserts proteins into bacterial outer membranes. Here, the authors show that hinge flexibility between BamA’s...
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Reposted by Anton Calabrese
Glenn Masson @glennmasson.bsky.social · 04/07/2025
Congratulations to Graham Neill who passed his PhD Viva today! 👏🎉👏🎉First PhD from the lab! Many thanks to Tony Ly from Dundee SLS and @antoncalabrese.bsky.social from Leeds for grilling Graham on all things kinases + hdx-ms. Read about Graham's Research on GCN2 here: www.biorxiv.org/content/10.1...
biorxiv.org
Paradoxical Activation of GCN2 by ATP-competitive inhibitors via allosteric activation and autophosphorylation
Recently it has been found that General Control Non-derepressible 2 (GCN2) can be activated by an array of small molecule ATP-competitive inhibitors, including clinically relevant compounds such as Po...
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Anton Calabrese @antoncalabrese.bsky.social · 06/05/2025
Delighted to share our latest preprint on the design of photoactivatable and lysine reactive oNBA-based reagents for chemical crosslinking-mass spectrometry. We think that these new tools will enable a range of novel structural proteomics applications! www.biorxiv.org/content/10.1...
biorxiv.org
Design and Characterisation of Photoactivatable and Lysine Reactive o-Nitrobenzyl Alcohol-Based Crosslinkers
Photoreactive groups are invaluable tools in structural proteomics, offering reagent-free activation and temporal control of protein labelling. However, traditional UV-activatable functional groups of...
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Reposted by Anton Calabrese
Elton Zeqiraj @zeqiraj.bsky.social · 17/03/2025
Amazing efforts from first author @francescachandler.bsky.social and collaborators Roger Greenberg, Joseph Salvino, Francesco Del Galdo and their teams. @pennmedicine.bsky.social @wistar.org @astburycentre.bsky.social @astbury-bsl.bsky.social @antoncalabrese.bsky.social @bioscienceleeds.bsky.social
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Anton Calabrese @antoncalabrese.bsky.social · 02/12/2024
Delighted to see our paper online in JACS! We studied the interaction of TDP-43 with RNA oligonucleotides by HDX-MS, and discovered RNA-sequence dependent differences in the mode of RNA engagement by the RRM domains @thom-mass.bsky.social @emilyjbyrd.bsky.social @monolejnik.bsky.social
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Anton Calabrese @antoncalabrese.bsky.social · 22/11/2024
We are looking for a PhD student to join our group, working on a collaborative project with Immunocore to use structural MS to improve the manufacturability of biopharmaceuticals - please pass on details to anyone who might be interested in the project. www.findaphd.com/phds/project...
findaphd.com
CASE Project: Overcoming host cell protein contamination in the preparation of biopharmaceuticals at University of Leeds on FindAPhD.com
PhD Project - CASE Project: Overcoming host cell protein contamination in the preparation of biopharmaceuticals at University of Leeds, listed on FindAPhD.com
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Anton Calabrese @antoncalabrese.bsky.social · 16/11/2024
Spending Saturday out and about with this guy… made sure to treat him to a puppacino for being such a good boy! 🐶
Labrador starting intently at a cup of whipped cream
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Anton Calabrese @antoncalabrese.bsky.social · 13/11/2024
👋🏻👋🏻 I work with fantastic team at the University of Leeds, and together we aim to develop and utilise mass spectrometry and biophysics to study protein structure/function. We are interested in intrinsically disordered proteins, chaperones, amyloids, viral proteins, condensates, ribosomes and more!
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