iiinova — where your digital self keeps evolving

Reposted by Sam Bloom

Metztli Cisneros-Aguirre @cisnerosmetztli.bsky.social · 05/11/2025

🧬Register for the GRS on DNA Damage, Mutation & Cancer🧬 Feb 28–Mar 1 2026, Ventura CA Accepting abstracts for oral presentations!  📍 Apply here 👉 grc.org/dna-damage-mutation-and-cancer-grs-conference/2026 (www.grc.org/dna-damage-m...) #DNADamage #GRC#GRS #CallForAbstracts

grc.org

2026 DNA Damage, Mutation and Cancer (GRS) Seminar GRC

The 2026 Gordon Research Seminar on DNA Damage, Mutation and Cancer (GRS) will be held in Ventura, California. Apply today to reserve your spot.

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Reposted by Sam Bloom

JStark lab @jstarklab.bsky.social · 05/11/2025

📢📢Apply now for GRS/GRC on DNA Damage Mutation & Cancer in sunny Ventura CA.

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Reposted by Sam Bloom

Joe Nassour @joenassour.bsky.social · 12/08/2025

Out now in CSH Perspectives in Biology (Telomeres & Telomerase) : “Telomere crisis shapes cancer evolution.” cshperspectives.cshlp.org/content/earl...

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Reposted by Sam Bloom

Genes & Development @genesdev.bsky.social · 20/08/2025

SYMPOSIUM OUTLOOK: #Telomeres at the nexus of #aging, #tumor suppression, and #inflammation: toward an understanding beyond #senescence By Samuel Bloom & Jan Karlseder ➡️ bit.ly/410dJwg #cshlsymp25 #DNAdamage #replicativesenescence #DNAreplication #crisis #cancer

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Reposted by Sam Bloom

Karlseder Lab @karlsederlab.bsky.social · 15/08/2025

Our lab’s latest “hot take” is out in Genes & Development! We argue for looking beyond senescence to understand how telomeres connect aging, tumor suppression, and inflammation. Great job @sambloom28.bsky.social! 👉 DOI: 10.1101/gad.353122.125 genesdev.cshlp.org/content/earl...

genesdev.cshlp.org

Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence

A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields

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Reposted by Sam Bloom

Joe Nassour @joenassour.bsky.social · 22/04/2025

New preprint out! We propose a “degradative flux” mechanism for tonic STING signaling in ALT+ cells, driven by IRF3-dependent trafficking and clearance of immunogenic extrachromosomal telomeric repeats—a process that could be targeted for cancer immunotherapy www.biorxiv.org/content/10.1...

biorxiv.org

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Reposted by Sam Bloom

Dawid Zyla @dzyla.bsky.social · 16/02/2025

I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz

mssearch.xyz

Streamlit

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Reposted by Sam Bloom

Karlseder Lab @karlsederlab.bsky.social · 07/02/2025

Huge thanks to Hannah Trost, Gabriel Matos Rodriguez, Roger Greenberg, and Hilda Pickett for an amazing Mammalian DNA Repair GRS/GRC in Ventura! Already excited for the next one!

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Reposted by Sam Bloom

Karlseder Lab @karlsederlab.bsky.social · 17/12/2024

With our lab’s inaugural Blue Sky post we celebrate our latest publication, a review in Nature Reviews Molecular Cell Biology (@natrevmcb.bsky.social) 🥳 Here, we review our current understanding of telomere biology, discussing differences between human and mouse. www.nature.com/articles/s41...

nature.com

Telomere function and regulation from mouse models to human ageing and disease - Nature Reviews Molecular Cell Biology

Telomere dysfunction, usually owing to shortening, activates cellular senescence and can contribute to age-associated diseases and cancer. Mouse models are crucial for telomere research, but human and...

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