samantlab.bsky.social @samantlab.bsky.social · 16/02/2026Check out Ubi-SCAPE! A tonne of hard work and thorough optimisations from Harvey went into getting the most out of the TUBE-based poly-ubiquitin #proteomics workflow; don't worry, we've kept the pre-print short… #TeamMassSpec 010
samantlab.bsky.social @samantlab.bsky.social · 08/08/2025We're recruiting a Research Assistant (new grant--details to follow!)--come help us work with primary human patient material to make cool 2D/3D co-culture systems, & learn about how #proteostasis & #senescence play together in these contexts: babrahaminstitute.livevacancies.co.uk#/job/details... 000
samantlab.bsky.social @samantlab.bsky.social · 15/05/2025A Good Week (TM) for the lab: first big grant, and now first #PhDone. 010
Reposted by @samantlab.bsky.socialSFB Targeted Protein Degradation @sfb-tpd-vienna.bsky.social · 13/05/2025After all the (re-)connections on day 1, day 2 of #ubfriends2025 even more fabulous for us 🤩 BIG THANKS to all the speakers & poster presenters for sharing their exciting research, and to EVERYONE who joined us! It was a true pleasure to host this amazing community👇 1245
Reposted by @samantlab.bsky.socialdelladavid-lab.bsky.social @delladavid-lab.bsky.social · 18/02/2025Exciting news: Registration for the 2025 UK Proteotasis & Autophagy meeting (3-5th June) is open: tinyurl.com/mr3p49f9tinyurl.comJoint 2025 Autophagy UK and Proteostasis UK conference | University of Dundee, UKWelcome to the 2025 joint “Autophagy UK and Proteostasis UK” conference! 053
Reposted by @samantlab.bsky.socialMolecular Cell @cp-molcell.bsky.social · 26/02/2025Online Now: Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions Online now:dlvr.itPredictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactionsSchmid and Walter train a classifier that discerns functionally relevant structure predictions in proteome-wide protein-protein interaction (PPI) screens using AlphaFold-Multimer, and they use this confidence metric to curate a database of 40,000… 0105
samantlab.bsky.social @samantlab.bsky.social · 14/02/2025#Proteostasis strategies diverge between cell states--and this matters! Beautiful, @slavovlab.bsky.social. Concept I first stumbled across in a Ghaemmaghami study (doi.org/10.1073/pnas.1710238114), and it's shaped my science ever since. Treasure-trove of data here for the coming weeks/months/years!doi.orgProteome-wide modulation of degradation dynamics in response to growth arrest | PNASIn dividing cells, cytoplasmic dilution is the dominant route of clearance for long-lived proteins whose inherent degradation is slower than the ce... 020
