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Sage Science

@sagescience.bsky.social
54 followers 191 following 7 posts

Specializing in DNA Size Selection and related technologies for DNA sequencing. We make the BluePippin, Pippin Prep, and PippinHT systems.

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Sage Science @sagescience.bsky.social · 18/09/2026
🧬 The PippinHT was part of the library prep behind the most complete vanilla genome to date — the first V. planifolia assembly anchored to all 16 chromosome pairs, out in BMC Genomics. SMRTbell libraries were size-selected at a 6 kb high-pass cutoff before PacBio HiFi. Open access:
link.springer.com
A chromosome-level genome assembly of Vanilla planifolia uncovers the genomic architecture underlying partial endoreplication - BMC Genomics
Background Partial endoreplication is a prominent developmental feature and poses a significant challenge for whole genome assembly in orchids. This form of cell cycle results in highly unbalanced cel...
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Sage Science @sagescience.bsky.social · 18/08/2026
PippinHT was part of the workflow behind the first complete genome of a songbird 🐦 Our >10 kbp size selection prepped the PacBio HiFi library for this fully phased, T2T zebra finch reference from @erichjarvis.bsky.social and @vertebrategenomes.bsky.social - now out in @cellpress.bsky.social
cell.com
The complete genome of a songbird
A phased diploid telomere-to-telomere reference genome for the zebra finch fully resolves its complete somatic chromosome set, recovering 2,710 previously missing or unannotated genes. The assembly al...
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Sage Science @sagescience.bsky.social · 22/07/2026
The Sage Science MegaPulse™ is here! A pulsed-field electrophoresis power supply supporting FIGE and ZIFE on standard agarose midi gels. 7 pre-validated protocols with 0.5 kb–1.6 Mb resolution. Built for HMW DNA analysis and long-read sequencing library prep. sagescience.com/blog/new-meg...
sagescience.com
New! MegaPulse Electrophoresis Power Supply | Sage Science
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Sage Science @sagescience.bsky.social · 20/07/2026
New citation! MASTR-seq harnesses BluePippin size selection to revolutionize short tandem repeat analysis for rare disease diagnostics. Multiplexed, accurate, single-molecule resolution. Read more: sagescience.com/citation/mas... | Full paper: doi.org/10.1016/j.cr...
sagescience.com
MASTR-seq enables multiplexed analysis of short tandem repeats with sequencing | Sage Science
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Reposted by Sage Science
JAX Genomic Education @jaxeducation.bsky.social · 11/02/2026
Thanks to the following sponsors who are supporting the 2026 JAX Long-Read Sequencing Workshop! @sagescience.bsky.social @twistbioscience.com @pacbio.bsky.social @nebiolabs.bsky.social @idtdna.bsky.social @rnaconnect.bsky.social @nabsys.bsky.social @iconpcr.bsky.social Illumina Sampled
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Sage Science @sagescience.bsky.social · 09/10/2025
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Sage Science @sagescience.bsky.social · 08/05/2025
Landmark study unravels the Oryza pangenome with an eye toward breeding more resilient rice strains for more sustainable agriculture. Led by Rod Wing at the Arizona Genomics Institute and #KAUST in collaboration with #Wageningen Univ. and others. Read our blog: sagescience.com/blog/uncateg...
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Sage Science @sagescience.bsky.social · 17/12/2024
Great review article from @cshlnews.bsky.social and @genomeresearch.bsky.social about the state-of-the-art of long-read targeted sequencing. From the “Long-Read Special Issue” genome.cshlp.org/content/34/1...
genome.cshlp.org
Leveraging the power of long reads for targeted sequencing
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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