sagarnigs.bsky.social @sagarnigs.bsky.social · 5hHappy to share that our research team got selected for MIT-MGH Seed Program funding to develop a novel portable device to assess fluid status in patients with heart failure and kidney disease. heals.mit.edu/mit-mgb-seed... 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 12/06/2026Successful treatment of pan-resistant NDM-1-producing Pseudomonas aeruginosa infection of calciphylaxis wounds with bacteriophage plus novel antibiotics- an instructive, innovative case that highlights multiD collaboration! @MGBKidneys www.thelancet.com/journals/lan...thelancet.comCalciphylaxis complicated by NDM-1-producing Pseudomonas aeruginosa: first experience with cefepime–zidebactam alongside phage therapy in the USAWe report a case of calciphylaxis—a rare vasculopathy characterised by arteriolar calcification and ischaemic skin necrosis—in a young woman with acute myeloid leukaemia. Her ulcerated skin lesions be... 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 07/05/2026Join us for a multidisciplinary, interactive, lunch session on hemodiafiltration (HDF) at SCM2026 tomorrow in New Orleans! I look forward to chairing this session. @nkf-professionals.bsky.social 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 01/03/2026Wound debridement in calciphylaxis is controversial. New paper highlights that in some patients debridement +/- skin graft may offer substantial benefits. Much to learn! Until then consult with an experienced surgeon is a way to go. onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.comWound Management and Surgery for Calcific Uremic Arteriolopathy (Calciphylaxis): A Retrospective Observational Cohort StudyWound care in calciphylaxis remains poorly defined without evidence-based consensus on timing and technique of surgical intervention. We demonstrate that surgical debridement and subsequent wound clo... 000
Reposted by @sagarnigs.bsky.socialMatt Sampson @kidneyomicsamps.bsky.social · 12/01/2026@janewit-thekidgene.bsky.social led this project wonderfully. Thanks also to @pnatarajanmd.bsky.social @sagarnigs.bsky.social for help w/MGBB, @genetickidneydoc.bsky.social & @jasayer.bsky.social for their collaboration, PIs contributing pts @gbadegesinlab.bsky.social & @thesampsonlab.bsky.social 161
sagarnigs.bsky.social @sagarnigs.bsky.social · 19/01/2026An instructive illustration of a remarkable improvement in calciphylaxis wound with continuous topical oxygen therapy in this publication …https://woundsinternational.com/journal-articles/mechanistic-insights-and-international-use-cases-of-continuous-topical-oxygen-therapy-in-wound-management/woundsinternational.comMechanistic insights and international use cases of continuous topical oxygen therapy in wound management – Wounds International 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 22/12/2025MGH Kidney Research Center Holiday Party 2025! 🙏for all the collaborations. 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 28/11/2025Skin Disorders in Kidney Disease: Core Curriculum 2026 - American Journal of Kidney Diseases ajkd.org/article/S027... Thankful for the opportunity to contribute to this Core Curriculum feature. 🙏ajkd.orgSkin Disorders in Kidney Disease: Core Curriculum 2026Skin disorders occur commonly in patients with chronic kidney disease (CKD) and may greatly impact their quality of life. These skin disorders have varying underlying pathophysiologies, but there are ... 032
sagarnigs.bsky.social @sagarnigs.bsky.social · 05/11/2025Don't Let It Go to Your Head: Hyponatremia and the Brain - Honoring Nicolaos Madias @American Society of Nephrology #Kidneyweek2025 NOVEMBER 06, 2025 | 10:30 AM CST - 12:30 PM CST I will be co-moderating with Dr. Mike Moritz. 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 25/10/2025I was in Barcelona last week for advanced learning about hemodiafiltration. First pic from the streets of Barcelona & the second one in waiting lounge of a dialysis unit in Barcelona…next to a beautiful mural drawn by one of their patients. 000
Reposted by @sagarnigs.bsky.socialASN Publications @asnpublications.bsky.social · 08/07/2025The July issue of Kidney News is now online! Topics covered this month include: - A special section on genetic kidney diseases - Key reflections from recent conferences - New insights into calciphylaxis therapy Explore the issue: kidney.pub/KN1707-01 #ASNKidneyNews @kdjhaveri.bsky.social 094
sagarnigs.bsky.social @sagarnigs.bsky.social · 03/07/2025In this patient centric qualitative research, we highlight the disease burden and challenges that patients with calciphylaxis experience - www.nature.com/articles/s41...nature.comNavigating the patient-provider relationship during severe illness with lessons from a qualitative perspective of calciphylaxis - Scientific ReportsScientific Reports - Navigating the patient-provider relationship during severe illness with lessons from a qualitative perspective of calciphylaxis 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 28/04/2025Fun serving as a moderator for this online discussion covering updates regarding ADPKD, IgAN and FSGS; Spring Clinical Meeting 2025. @nkf-professionals.bsky.social @medpagetoday.bsky.social www.medpagetoday.com/meetingcover...medpagetoday.comGuiding Practice Through the Latest KDIGO Guidelines on ADPKDExperts parse new risk scores and tolvaptan safeguards 011
sagarnigs.bsky.social @sagarnigs.bsky.social · 23/04/2025We are excited to share this work done in collaboration with Chitalia Lab (BUMC) on elucidating the molecular pathogenesis of thrombosis in the development of calciphylaxis with an eventual goal to develop targeted therapies. www.science.org/doi/10.1126/...science.orgActivation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxisMicrovascular thrombi in calciphylaxis skin can be pharmacologically targeted by anti–IL-6 therapies. 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 22/04/2025Our Kidney Research Center had an amazing visit from Dr. Len Usvyat and his team from the Renal Research Institute (RRI) where we discussed ongoing research projects and opportunities to collaborate. @massgeneralbrigham.bsky.social 000
sagarnigs.bsky.social @sagarnigs.bsky.social · 15/04/2025Ten Tips on How to Deal with Calciphylaxis Patient academic.oup.com/ckj/article/... Thanks to @Api Chewcharat for leading this write up.academic.oup.comTen Tips on How to Deal with Calciphylaxis PatientAbstract. Calciphylaxis is a devastating disease characterized by excruciatingly painful ischemic necrotic lesions predominantly affecting patients with en 032
sagarnigs.bsky.social @sagarnigs.bsky.social · 15/04/2025Multicenter Evaluation of Certainty and Reliability in Calciphylaxis Diagnosis using a Digital Imaging Platform - Laboratory Investigation laboratoryinvestigation.org/article/S002... Great leadership on this paper by outstanding pathologist Dr. Rosalynn Nazarian.laboratoryinvestigation.orgMulticenter Evaluation of Certainty and Reliability in Calciphylaxis Diagnosis using a Digital Imaging PlatformThe robustness of histopathologic criteria for diagnosing calciphylaxis depends both on dermatopathologists' confidence in recognition of individual histologic features and on the inter-rater reliabil... 031
sagarnigs.bsky.social @sagarnigs.bsky.social · 09/12/2024Dis-impede the Achievement of Euvolemia in Kidney Failure : journals.lww.com/cjasn/abstra... Honored to co-author this editorial & collaborate with Dr. Michael Cima on an ongoing study of NMR device to assess volume in dialysis patients.journals.lww.comDis-impede the Achievement of Euvolemia in Kidney Failure : Clinical Journal of the American Society of NephrologyAn abstract is unavailable. 010
