Saad Yousuf PhD @saadyousuf.bsky.social · 26/06/2025A wonderful team effort with @tedpricethepainguy.bsky.social, @dianatavf.bsky.social and collaborators at Merck. This is a great example of collaboration across academia and industry. Grateful for the synergy that made this work possible. 040
Saad Yousuf PhD @saadyousuf.bsky.social · 26/06/2025Excited to share our preprint on spatial transcriptomics of human sympathetic chain ganglia and the effect of diabetes. We also compared sympathetic and dorsal root ganglia to identify ganglia-specific signatures. Work led by @marisolmancilla.bsky.social doi.org/10.1101/2025...doi.orgSpatial transcriptomic profiling of human paravertebral sympathetic chain ganglia reveals diabetes-induced neuroplasticityThe paravertebral sympathetic chain ganglia (SCG) are autonomic ganglia critical for regulating the fight-or-flight response. Symptoms of sympathetic dysfunction are prevalent in diabetes, affecting u... 2156
Reposted by Saad Yousuf PhDTed Price @tedpricethepainguy.bsky.social · 22/11/2023Our collaborative paper with Isaac Chiu's lab was published today: www.sciencedirect.com/science/arti... It is a really cool finding on how Staphylococcus V8 protease drives the itch-scratch cycle via PAR1 activation. We did the human DRG work. Huge congrats to Liwen Deng, who led this work.sciencedirect.comS. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axisItch is an unpleasant sensation that evokes a desire to scratch. The skin barrier is constantly exposed to microbes and their products. However, the r… 1104
Reposted by Saad Yousuf PhDTed Price @tedpricethepainguy.bsky.social · 18/10/2023We received positive reviews on our work on TMEM97 modulators for neuropathic pain and have now posted a revision to our paper on @biorxiv-neursci.bsky.social @biorxiv-bioinfo.bsky.social www.biorxiv.org/content/10.1... led by Saad Yousuf in my lab and Jim Sahn in Stephen Martin's lab at UT Austinbiorxiv.orgHighly specific σ2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress re...bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution 161
