Excited to share our preprint on spatial transcriptomics of human sympathetic chain ganglia and the effect of diabetes. We also compared sympathetic and dorsal root ganglia to identify ganglia-specific signatures. Work led by @marisolmancilla.bsky.social
doi.org/10.1101/2025...
doi.org
Spatial transcriptomic profiling of human paravertebral sympathetic chain ganglia reveals diabetes-induced neuroplasticity
The paravertebral sympathetic chain ganglia (SCG) are autonomic ganglia critical for regulating the fight-or-flight response. Symptoms of sympathetic dysfunction are prevalent in diabetes, affecting u...
