Combinatorial use of an antibody–reporter enzyme conjugate and a fluorescence probe activated by the enzyme is a powerful strategy for fluorescence-guided cancer surgery. However, conventional probes ...

Tumor-derived extracellular vesicles cross the kidney filter into urine via glomerular transcytosis, enabling urinary diagnostics.

抗原に結合するだけで光る蛍光プローブの新規設計法に関する論文がJACSで公開になりました! 日本語プレスリリースはこちらです。@jacs.acspublications.org https://www.u-tokyo.ac.jp/content/400268162.pdf [contains quote post or other embedded content]

Phage-assisted noncontinuous selection of protein binders (PANCS-Binders) allows multiple high-diversity protein libraries to each be screened against a panel of dozens of targets for high-throughput ...

Fluorogenic probes for antigens are useful for various purposes, including medical diagnostics and imaging, but achieving a rapid, large fluorescence increase is difficult. Here, we report a new class...

Fluorogenic probes for antigens are useful for various purposes, including medical diagnostics and imaging, but achieving a rapid, large fluorescence increase is difficult. Here, we report a new class...

Combinatorial use of an antibody-reporter enzyme conjugate and a fluorescence probe activated by the enzyme is a powerful strategy for fluorescence-guided cancer surgery. However, conventional probes ...

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Fluorogenic probes for antigens are useful for various purposes, including medical diagnostics and imaging, but achieving a rapid, large fluorescence increase is difficult. Here, we report a new class...

Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The...

The release processes of small extracellular vesicles (sEVs) remain poorly understood despite their importance. Here, Kunitake et al. present a screening platform called CIBER screening that enables e...