Our new paper is out in @jacs.acspublications.org
! We developed a novel pair of bioorthogonal fluorescence probe and engineered reporter enzyme, enabling low-background, bright cancer imaging in vivo. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Low-Background Cancer Imaging with a Bioorthogonal Fluorescence Probe and Engineered Reporter Enzyme Bearing a Targeting Moiety
Combinatorial use of an antibody–reporter enzyme conjugate and a fluorescence probe activated by the enzyme is a powerful strategy for fluorescence-guided cancer surgery. However, conventional probes ...