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Raju Tomer

@rtomer.bsky.social
72 followers 59 following 17 posts

Associate Prof. @ Columbia University

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Raju Tomer @rtomer.bsky.social · 22/06/2026
Nat. Biotech. Brief. on our hybrid solid-liq optics work rdcu.be/fpLtj rdcu.be/fnktk Much thanks to Jan Huisken for expert opinion: "The HySIL concept represents a genuine advance..The authors tackle a notable limitation in the field: achieving submicrometer resolution over centimeter-scale volumes"
rdcu.be
Affordable centimeter-scale 3D microscopy with submicrometer resolution
Nature Biotechnology - Submicrometer-resolution three-dimensional (3D) imaging of large samples has been constrained by the short working distance, high cost and inflexible design of immersion...
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Raju Tomer @rtomer.bsky.social · 19/06/2026
www.youtube.com/watch?v=3-gR...
youtube.com
Imaging Breakthroughs Could Change How we View Cells
YouTube video by Photonics Media
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Raju Tomer @rtomer.bsky.social · 09/06/2026
HySIL / pLSM-SCOPE / SLICE work out now in Nature Biotechnology (open article)!
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Reto Fiolka @retof.bsky.social · 05/05/2026
@rtomer.bsky.social : Pizza time at AQLM! @aqlm.bsky.social !
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Raju Tomer @rtomer.bsky.social · 20/12/2025
Are we born as a blank slate, or with a neural “operating system”? We show hippocampal neurons self-organize into memory-like networks in a dish. We also introduce IncStim, a compact, all-optical sys. for closed-loop act. imaging/manipulation inside an incubator. www.biorxiv.org/content/10.6...
biorxiv.org
In vitro reconstitution of hippocampal cell assemblies
Three-dimensional neuronal cultures, such as brain organoids, have proven effective for in vitro modeling of brain development and disease. However, it remains unclear whether these systems can intrin...
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Raju Tomer @rtomer.bsky.social · 04/11/2025
Sharing new work from us+collaborators. We take a step toward making organ-scale, subcellular 3D imaging as scalable & affordable as next-gen sequencing, to eventually fuel next-gen of AI-foundational models of tissues, organs. www.biorxiv.org/content/10.1... Videos: www.youtube.com/playlist?lis...
youtube.com
Scalable, affordable, submicron 3D imaging of multi-centimeter scale samples. - YouTube
Hybrid Solid-Liquid Optics Enable Scalable, High-Resolution, Multi-Immersion Light-Sheet Microscopy. Authors: Cheng Gong, Pauline Affatato, Matt Fay, Sudha R...
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Raju Tomer @rtomer.bsky.social · 03/10/2025
A milestone worth reflecting on - 1000 citations for our cleared tissue light sheet paper - the COLM. Gratifying that core ideas have stood the test of time and are broadly adopted: Cuvette-based sample mounting; Virtual slit effect with rolling shutter CMOS; and Linear adaptive offset correction!
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Raju Tomer @rtomer.bsky.social · 28/08/2025
Love this!! I don’t think I’ve ever seen anything like this before -- high-res light sheet microscopes designated for use by individual researchers in one lab!! Fantastic to see real-world impact emerging, starting with Bianca’s lab at JLG, Columbia!
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MBF Bioscience @mbfbioscience.bsky.social · 05/05/2025
We’re proud to work with Dr. Tomer & his team at Columbia University to bring SLICE to life, a compact, affordable light-sheet microscope making 3D imaging more accessible worldwide. 📖 magazine.columbia.edu/article/3d-i... @rtomer.bsky.social @columbiauniversity.bsky.social #SLICE #lightsheet
magazine.columbia.edu
3D Imaging Just Got Easier
Columbia researchers have developed a powerful new microscope that could enable more scientists around the world to conduct cutting-edge biomedical research.
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MBF Bioscience @mbfbioscience.bsky.social · 16/04/2025
We had to join the trend. Introducing: Jack Glaser, Founder and President of MBF Bioscience —now an action figure. Complete with microscope, field journal, and trusty lab dog. 🧠🐕 In science, there are no small people—just big ideas. #ScienceMatters #STEM #Microscopy
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Eric Topol @erictopol.bsky.social · 20/03/2025
Our digital times :-)
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Eric Topol @erictopol.bsky.social · 18/03/2025
Quite an essay on the basis of cancer entitled "The End of the Genetic Paradigm of Cancer" @plosbiology.org arguing against the primacy of somatic mutations (traditional model) and cells, invoking gene regulatory networks and tissue journals.plos.org/plosbiology/...
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Loren Looger lab @loogerl.bsky.social · 19/12/2024
have ppl found any funders that support toolmaking? I want to keep making tools for people, but there is a seemingly irresistible force pushing us towards hypothesis-driven research. In my experience, funders don't want to hear about tech dev. Any insights? for both neuro & climate would be great tx
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Franck Polleux @franckp.bsky.social · 18/12/2024
Delighted to highlight our new paper in @natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
nature.com
Synaptic basis of feature selectivity in hippocampal neurons - Nature
A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.
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