Reposted by Rodolpho SouzaAgathe Chaigne @agathechaigne.bsky.social · 24/09/2026I'm super proud of this review written (mostly) by Zoé Ducarne and @myanhtruong.bsky.social about the extraordinary genomic features of the placenta. Such a crazy organ! journals.biologists.com/dev/article/...journals.biologists.comThe curious case of the placental genomeSummary: The placenta is the only mammalian organ that harbors a cancer-like genome while remaining functional and healthy. This Review highlights its high mutational load, structural variants, aneupl... 23917
Reposted by Rodolpho SouzabioRxiv Microbiology @biorxiv-microbiol.bsky.social · 31/08/2026Discovering 25 novel phyla that fill gaps in the eukaryotic tree of life www.biorxiv.org/content/10.64898/20… 021
Reposted by Rodolpho SouzaJiménez-Ruiz Lab @jimenezruizlab.bsky.social · 27/08/2026The study focuses on PCKMT, AKMT and the Plasmodium enzyme PfSET9. Check it out here: www.nature.com/articles/s41... #Apicomplexa #Methylation #CellMotility #Toxoplasma #Plasmodiumnature.comDual apical methyltransferases orchestrate motility initiation in apicomplexan parasites - Nature CommunicationsThis study identifies the Apicomplexa-specific methyltransferase PCKMT and reveals how it works with the previously known AKMT in a two-step pathway that initiates parasite motility and invasion. 051
Reposted by Rodolpho SouzaTobias Warnecke @tobiaswarnecke.bsky.social · 22/08/2026Who needs chromatin anyway...? NOT THIS GUY! www.biorxiv.org/content/10.6... 1/nbiorxiv.orgChromatin is dispensable for bacterial lifeInside cells, DNA is intimately associated with proteins, forming chromatin. The protein constituents of chromatin vary across the tree of life: histones are the principal building blocks of chromatin... 3231104
Reposted by Rodolpho SouzaHolly Moeller @mixotrophe.bsky.social · 07/08/2026Freaking finally! A massive compilation of data that sat on various desks for almost a decade is finally out. On the positive side, gave me time to learn expansion microscopy and make Fig 1 www.science.org/doi/10.1126/...science.orgEmergent metabolic parasitism driven by organelle sequestrationChloroplast-stealing ciliates evolve, increasing reliance on their prey for all aspects of metabolism, including photosynthesis. 26320
Reposted by Rodolpho SouzaPLOS Biology @plosbiology.org · 05/08/2026Graphing and statistically analyzing data is challenging without coding expertise. This Community Page by @avishenoy.bsky.social introduces grafify online, a free, browser app for generating publication-quality graphs and performing statistical tests and comparisons. 🧪 #AcademicSky plos.io/3RpUg6E 0126
Reposted by Rodolpho SouzaSheinerLab @sheinerlab.bsky.social · 03/08/2026We knew Toxoplasma Type I needs fats to survive in culture. Now we show this in Toxoplasma Type II, responsible for most human infections in Europe and North America. Blocking fatty acid elongation reduced growth and persistence in lab culture and in animals. www.biorxiv.org/content/10.6... 082
Reposted by Rodolpho SouzabioRxiv Microbiology @biorxiv-microbiol.bsky.social · 22/07/2026Cryptosporidium sequentially remodels its single rhoptry into the host interface www.biorxiv.org/content/10.64898/20… 031
Reposted by Rodolpho SouzaPLOS Biology @plosbiology.org · 20/07/2026Regulation of gene expression in the #parasite #Leishmania is largely post-transcriptional, but how is it controlled? This study shows that modification of tRNAs by #quenosine influences codon-biased translation and contributes to Leishmania virulence @plosbiology.org 🧪 plos.io/4bwvAjs 193
Reposted by Rodolpho SouzaNature Microbiology @natmicrobiol.nature.com · 30/04/2026Out Now! Prioritizing prenatal screening to prevent Chagas disease #MicroSkygo.nature.comPrioritizing prenatal screening to prevent Chagas diseaseNature Microbiology, Published online: 30 April 2026; doi:10.1038/s41564-026-02342-2Prioritizing prenatal screening to prevent Chagas disease 053
Rodolpho Souza @rodolphosouza1.bsky.social · 10/04/2026We have a new preprint out! This time, we discovered that correct mitochondrial positioning in Toxoplasma is important for the metabolism of key cofactors and for sensing conditions that drive parasite egress. www.biorxiv.org/content/10.6...biorxiv.org 020
Reposted by Rodolpho SouzaGroovy Tasia @groovytasia.bsky.social · 08/04/2026Sorry I was late to the meeting. The dog had to spin around 80 times to make sure he was pooping at the right angle. 1232904159
Reposted by Rodolpho SouzaJournal of Cell Science @jcellsci.bsky.social · 07/04/2026In their Review, Prasanna Katti, Antentor Hinton, Jr and colleagues discuss how imaging techniques have advanced our understanding of mitochondrial biology. journals.biologists.com/jcs/article/... 0125
Reposted by Rodolpho SouzaEva Frickel @frickellab.bsky.social · 04/03/2026Hot off the biorxiv press! 🔥 Samuel Lara-Reyna finds GBP5 enhances macrophage glycolysis via glucose uptake, GTPase activity dependent and as being cis-Golgi localised. Bonus finding, GBP5 is important for full M1 macrophage functionality. www.biorxiv.org/content/10.6... 181
Reposted by Rodolpho SouzaLabEx ParaFrap @parafrap.bsky.social · 24/02/2026📆 Join the 2026 Biology of Host–Parasite Interactions GRC (June 7–12, Newport, RI) 🌟 Cutting-edge science, open slots for talks & posters 🧑🔬 GRS for grad students & postdocs the weekend before 📩 Apply by May 18, 2026 (early submission encouraged) 👉 Details & application: www.grc.org/biology-of-h... 022
Reposted by Rodolpho SouzaRafael Polidoro @rafaelpolidoro.bsky.social · 25/01/2026As the review process goes, take a sneak peak of our exciting manuscript. I'll make a proper thread when it's fully out!biorxiv.org 021
Reposted by Rodolpho SouzaIra Blader @bladerlab.bsky.social · 14/01/2026Interested in how infections cause seizures? Then, read on! We discovered that Toxoplasma selectively eliminates inhibitory synapses in brain. You will study how these synapses are removed. Please send brief review of research interests and goals, CV, and names of 3 refs to: iblader@vt.edu. 042
Reposted by Rodolpho SouzaJournal of Cell Science @jcellsci.bsky.social · 13/01/2026Isadonna Tengganu and Ke Hu develop transfection and ExM protocols for Chromera velia, enabling direct comparisons with its parasitic apicomplexan relative, Toxoplasma gondi. journals.biologists.com/jcs/article/... 03714
Reposted by Rodolpho SouzaStirling Churchman @stirlingchurchman.bsky.social · 03/12/2025Oxidative phosphorylation complexes contain subunits encoded by both the nuclear and mitochondrial genomes. How do cells coordinate the synthesis and assembly of these complexes at the inner membrane? We teamed up with Martin Ott (@mitolab.bsky.social) to address this in two recent papers. 18131
Reposted by Rodolpho SouzaToxo18 Brasil @toxo18.bsky.social · 23/10/2025Save the date‼️ 💡 More information coming soon about registration and the scientific program. #TOXO18 #Toxoplasma #Immunoparasitology #Buzios2026 #ScienceByTheSea 067
Reposted by Rodolpho SouzaArnau Sebé-Pedrós @arnausebe.bsky.social · 24/09/2025Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41... 4230107
Reposted by Rodolpho SouzaOded Rechavi @odedrechavi.bsky.social · 19/09/2025Geographic distribution of human toxoplasmosis 1343
Reposted by Rodolpho SouzaPLOS Biology @plosbiology.org · 22/07/2025#Mitochondrial proteins are synthesized with presequences that target them to the #mitochondrion, but why are some more efficient than others? This study identifies presequences which recruit Hsp90 co-chaperones & TOMM34 to confer prioritized import efficiency @plosbiology.org 🧪 plos.io/4m6spBN 0143
Reposted by Rodolpho SouzaPLOS Biology @plosbiology.org · 10/02/2025Aye-ayes are clearly unusual, but @glom.bsky.social @3rdreviewer.bsky.social &co show that they also have an unusual pattern of #MutationBias; older females transmit more mutations than males. This is a first for mammals, raising questions about other #lemurs 🧪 @plosbiology.org plos.io/40SR4kj 0239
Reposted by Rodolpho SouzaMegan Sloan @sloanmegan.bsky.social · 05/02/2025Excited to be able to share our new paper 'Iron Mediated Post-Transcriptional Regulation in Toxoplasma gondii'! Thanks to all involved including the awesome @clarehardinglab.bsky.social and @danaaghabi.bsky.social! journals.plos.org/plospathogen.... Read on for quick-read digest of our new work...journals.plos.orgIron-mediated post-transcriptional regulation in Toxoplasma gondiiAuthor summary Although iron is essential for most cells, excess can be toxic, so uptake and storage must be carefully controlled. The ability to respond to iron is particularly important for parasite... 4278
Rodolpho Souza @rodolphosouza1.bsky.social · 18/11/2024I haven’t posted anything yet, but my first post shows my new city and my best paw. He’s not a Colts fan anymore. 050