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Rikeish R Muralitharan MD, PhD

@rikeish.bsky.social
159 followers 188 following 20 posts

Research Fellow @FZMarques lab, @monashbiol Gut microbiome. Immune system. Diet. SCFAs. Hypertension. he/him

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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 02/02/2026
New paper from our team 🧠🦠 After stroke, gut‑derived bacteria can migrate into the brain Blocking sympathetic tone ↓ gut permeability, ↓ brain bacterial load, and improves motor outcomes—without changing infarct size Congrats to Dr Alex Peh! www.tandfonline.com/doi/full/10....
tandfonline.com
Gut bacteria presence in the brain is increased after ischemic stroke in mice
Systemic infections are a common cause of complications and death after stroke. These infections can occur due to the breakdown of the gut epithelial barrier and the translocation of bacteria from ...
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 17/11/2025
Thank you for the recognition! Grateful for the support from @fzmarques.bsky.social and Malindi, PhD student, lead coordinator for the study. Also to High BP Foundation for the seed funding!
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 12/10/2025
Congratulations Dr Lizzie Kleeman, Dr Carol Gubert, @anthonyjhannan.bsky.social & co-authors 👏👏👏 Thank you for the invitation for @rikeish.bsky.social and I to help with the #microbiome analysis requested by reviewers - a pleasure to work with you as always @natureportfolio.nature.com
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 12/08/2025
🚀 Big milestone achieved! GRAINS-BP trial is officially underway as we’ve randomised our first participant. Huge thanks to @fzmarques.bsky.social, our collaborators, funders, and PhD student Malindi. 🙌 For more information and recruitment, please check out www.marqueslab.com/trials
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 26/05/2025
Our latest paper is out in Cardiovascular Research We used a genetics approach to provide human evidence of gut-to-host crosstalk in how blood pressure is regulated Authors include Leticia Camargo Tavares, @mattsnelson.bsky.social @rikeish.bsky.social academic.oup.com/cardiovascre...
academic.oup.com
Rare pathogenic variants in G-protein-coupled receptor genes involved in gut-to-host communication are associated with cardiovascular disease risk
Gut microbial metabolites called short-chain fatty acids (SCFAs) confer protection against cardiovascular disease (CVD) and its primary risk factor, hypert
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 26/05/2025
Our review on the gut-heart axis published in Circ Res is now out www.ahajournals.org/doi/10.1161/... We cover gut #microbiome, 'leaky gut', foods & metabolites, +++ Congratulations @mattsnelson.bsky.social @rikeish.bsky.social and our co-authors 👏
ahajournals.org
American Heart Association Journals
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 18/05/2025
🧠🦠Can the gut communicate with the brain to regulate BP? Our latest review explores how microbial metabolites (SCFAs) may regulate BP via the gut–brain axis. A promising new frontier for hypertension treatment. 📖 Read more: doi.org/10.1042/CS20...
doi.org
Cross-talk between microbiota–gut–brain axis and blood pressure regulation
Hypertension, or high blood pressure (BP), is a widespread condition affecting one in three adults globally. Despite the availability of treatment options, 50% of hypertensive patients in countries su...
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 18/05/2025
🚨 EMCRs in cardiovascular research! Join our free webinar on the NHMRC Investigator Grant Scheme 🧠 📅 June 3 | 🕥 10:30am–12:00pm ACST 💡 Hear from successful applicants & peer reviewers 🔗 Register now: monash.zoom.us/webinar/regist… #NHMRC #CardioResearch #EMCR #SACVRN #VicCVRN
monash.zoom.us
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Reposted by Rikeish R Muralitharan MD, PhD
Gut Microbiota for Health @gmfhx.bsky.social · 26/03/2025
Could the connection between the #gutmicrobiome and hypertension pave the way to better management strategies? New findings in mice provide clues:
ahajournals.org
Gut Microbiota Metabolites Sensed by Host GPR41/43 Protect Against Hypertension | Circulation Research
BACKGROUND: Fermentation of dietary fiber by the gut microbiota leads to the production of metabolites called short-chain fatty acids, which lower blood pressure and exert cardioprotective effects. Short-chain fatty acids activate host signaling responses via the functionally redundant receptors GPR...
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Reposted by Rikeish R Muralitharan MD, PhD
Eric Topol @erictopol.bsky.social · 13/03/2025
How a fat in our diet (omega-6 linoleic acid)—a dietary long-chain polyunsaturated fatty acid) has the potential to promote tumor growth www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... @science.org
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 13/02/2025
Congrats @rikeish.bsky.social for your immunofluorescence image making it to the cover 👏👏👏 www.ahajournals.org/journal/res Also read the ‘Meet the first author’ and accompanying editorial (thanks @annetkiraboc1.bsky.social 👏👏👏) Paper and 🧵 👇 www.ahajournals.org/doi/full/10....
ahajournals.org
American Heart Association Journals
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 06/02/2025
Super excited to join @ahajournals.bsky.social Hypertension as an #ECR editorial assistant!
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Reposted by Rikeish R Muralitharan MD, PhD
Annet Kirabo D.V.M., M.Sc., Ph.D., F.A.H.A. @annetkiraboc1.bsky.social · 04/02/2025
Interesting breakdown by @fzmarques.bluesky.social & @rikeish.bsky.social on how the gut #microbiome shapes #bloodpressure of their paper published in #CircRes. 📝 Blog: www.marqueslab.com/post/underst… 📄 Paper: www.ahajournals.org/doi/10.1161/��� #Hypertension @ahajournals.bsky.social
marqueslab.com
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 30/01/2025
I am super proud and excited to share my latest publication, out now in @ahajournals.bsky.social (www.ahajournals.org/doi/10.1161/...)
ahajournals.org
Gut Microbiota Metabolites Sensed by Host GPR41/43 Protect Against Hypertension | Circulation Research
BACKGROUND: Fermentation of dietary fiber by the gut microbiota leads to the production of metabolites called short-chain fatty acids, which lower blood pressure and exert cardioprotective effects. Sh...
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 23/01/2025
www.science.org/content/arti...
science.org
People are bad at reporting what they eat. That’s a problem for dietary research
Studies that use surveys to link dietary patterns to human health may be irredeemably biased, new paper suggests
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Reposted by Rikeish R Muralitharan MD, PhD
Eric Topol @erictopol.bsky.social · 23/01/2025
The impact of a non-industrialized ("Restore") diet plus a key microbe on improving cardiometaboiic health markers and reducing body-wide inflammation, from a randomized trial www.cell.com/cell/fulltex... @cellpress.bsky.social open-access
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Reposted by Rikeish R Muralitharan MD, PhD
Eric Topol @erictopol.bsky.social · 13/01/2025
The gut microbiome products and..... —propensity to eat foods high in sugar nature.com/articles/s41... —accelerating cellular senescence nature.com/articles/s43...
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Reposted by Rikeish R Muralitharan MD, PhD
🦋 Gourdon Lab 🦠🔬 @delphe.bsky.social · 14/01/2025
🔔🧪 #Women, even in well-represented #scientific fields, are up to 40% more likely than men to leave #research within 20 years (Nature News). Urgent #action is needed to close the #scissor-shaped curve. #WomenInSTEM #genderequity #diversity #STEM www.nature.com/articles/d41...
nature.com
Who’s quitting academia? Data reveal gender gaps in surprising fields
Even in scientific areas in which women are well represented, they are up to 40% more likely than men to leave research within 20 years.
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 14/01/2025
Why are microbiome studies poorly translated or reproducible? We wrote an editorial to highlight the importance of considering and minimizing confounder effect in gut microbiome studies. @fzmarques.bsky.social @monashbiol.bsky.social academic.oup.com/cardiovascre...
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 08/01/2025
Another day, another paper 🙃 This paper was inspired by my journey as a cancer patient & the type of leader I am in the journey of trying to become A great read to start the year aiming to drive a more positive, equitable, and diverse research culture www.ahajournals.org/doi/10.1161/...
ahajournals.org
Rethinking Culture to Unlock the Potential of Medical Research | Hypertension
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 15/12/2024
Research Rockstar Award 🏆 For achieving the highest number of peer-reviewed recognition (across awards and papers) Nominees: everyone! Total of 54 awards Runner up: Charlotte Barker (10 awards) Winners: @mattsnelson.bsky.social and @rikeish.bsky.social (11 awards or 1st/last author papers each)
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 15/12/2024
#ecrchat #phdchat #womeninSTEM #womeninleadership #researchculture #workplaceculture #phdlife #labawards @monashuniversity.bsky.social @monashbiol.bsky.social
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Rikeish R Muralitharan MD, PhD @rikeish.bsky.social · 03/12/2024
The CV sector has created a joint submission for the @nhmrc urging them to reconsider the proposed changes to the eligibility requirement for Emerging Leadership (EL) applicants. Please read and make your own submission before Dec 4 ozheart.org/joint-submis...
ozheart.org
Joint submission on the proposed NHMRC updates to the Investigator Grant eligibility
The public consultation by the National Health and Medical Research Council (NHMRC) on proposed updates to the Investigator and Synergy Grant assessment framewo
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Reposted by Rikeish R Muralitharan MD, PhD
Prof Francine Marques @fzmarques.bsky.social · 29/11/2024
Congratulations to our team members at ☺️#Hypertension Australia 🤩 Dr Joanne O’Donnell - winner of the Judith Withworth Award for highest ranked abstract by a female first author Evany Dinakis - winner of the Student Oral Award (project funded by Heart Foundation) #hypertensionASM2024
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Reposted by Rikeish R Muralitharan MD, PhD
Altmetric @altmetric.com · 18/11/2024
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how: docs.bsky.app/docs/advance... #AcademicSky #HigherEd #Altmetrics
docs.bsky.app
Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
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