Reposted by Rhys Parry
Curious about how orthoflaviviruses coordinate viral RNA replication and virion assembly? Us too. And as it turns out, it takes 2 (2 NS2As that is)! journals.plos.org/plospathogen...
journals.plos.org
Zika virus produces two isoforms of the NS2A protein that play mutually exclusive roles in viral replication and virion assembly
Author summary The Orthoflavivirus NS2A protein is a small, hydrophobic, integral membrane protein implicated in both viral RNA replication and virion assembly. However, how NS2A participates in these...