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Renil Mathew

@renilmathew.bsky.social
51 followers 102 following 13 posts

Neuroscience PhD, Western University 🇨🇦. Multimodal fMRI 🐒 👳🏾‍♂️

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Reposted by Renil Mathew
tor @torwager.bsky.social · 02/09/2026
This book took about 10 years to write (or longer, depending on how you count)...I am fully on board with #SlowScience! mitpress.mit.edu/97802620450... Here are some tutorials that run example code in-browser, no back-end server or setup. #JupyterLite magic! torwager.github.io/elements-of...
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Renil Mathew @renilmathew.bsky.social · 23/06/2026
Thank you Ravi!
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Reposted by Renil Mathew
Ravi Menon @northernthrux.bsky.social · 04/06/2026
Guess who's celebrating a 30th anniversary? With massive thanks to years of support from @westernu.ca @schulichmeddent.bsky.social @lhsccanada.bsky.social @braincanada.bsky.social @innovation.ca @brukercorporation.bsky.social Siemens Healthineers, Gov. of Ontario www.schulich.uwo.ca/about/news-e...
schulich.uwo.ca
Western’s CFMM marks 30 years of imaging discovery - Schulich School of Medicine & Dentistry - Western University
Researchers have transformed understanding of the brain, healthy aging and disease.
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Ravi Menon @northernthrux.bsky.social · 30/04/2026
Heading to Montreal to give the Feindel Brain and Mind Seminar on Monday, May 4th. Honoured and touched, because Bill Feindel and I shared an office at @theneuro.bsky.social during my M.Sc. work at McGill. The work I will present comes from @renilmathew.bsky.social doctoral research.
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Reposted by Renil Mathew
Agnès Landemard @agnesland.bsky.social · 15/04/2026
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states! Out today in Nature: rdcu.be/fdC2A @uclbrainscience.bsky.social
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
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Reposted by Renil Mathew
Ravi Menon @northernthrux.bsky.social · 21/01/2026
Excited to give the Feindel Lecture at The Neuro on Monday 26th Jan in Montreal. Streamed and recorded too. Come hear about our new SASS MRI technique just out in print in @natmethods.nature.com @westernuwin.bsky.social @theneuro.bsky.social
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Reposted by Renil Mathew
Ravi Menon @northernthrux.bsky.social · 12/01/2026
Our article on using non-steady-state scans for event related fMRI is now out in print (remember print?). www.nature.com/articles/s41... And as a bonus, the journal (Nature Methods), did a News & Views piece www.nature.com/articles/s41... Lead author @renilmathew.bsky.social
nature.com
Client Challenge
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Renil Mathew @renilmathew.bsky.social · 29/12/2025
News and views article on SASS-fMRI from Nature methods. www.nature.com/articles/s41...
nature.com
Taking advantage of non-steady-state imaging to increase temporal SNR for fMRI - Nature Methods
A technique called SASS increases temporal signal-to-noise ratio for functional MRI by taking advantage of the time it takes to reach steady state when collecting functional images.
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Renil Mathew @renilmathew.bsky.social · 04/12/2025
Great honour to receive Dr Tutis Villis Graduate Award in Neuroscience. 🙏
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Reposted by Renil Mathew
Matthias Nau @matthiasnau.bsky.social · 24/11/2025
Just published my "Programming for Psychologists" course! 👩‍💻 github.com/Naubody/prog... Designed for Psychology & Cognitive Neuroscience Master's students starting their programming journey at @vuamsterdam.bsky.social. Feel free to share! Feedback welcome!
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Nature Methods @natmethods.nature.com · 20/11/2025
Stimulus-modulated approach to steady state (SASS): an acquisition scheme for event-related fMRI that generates data interspaced with acquisition-free periods for stimulus presentation or response reporting. @renilmathew.bsky.social @northernthrux.bsky.social www.nature.com/articles/s41...
nature.com
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods
Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...
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Reposted by Renil Mathew
Western University @westernu.ca · 14/11/2025
#WesternU researchers have unlocked the hidden potential in discarded MRI data, developing a new technique transforming how scientists study the brain. @schulichmeddent.bsky.social
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Signal in the silence: Western researchers uncover hidden potential in discarded MRI data - Western News
Western University researchers have uncovered hidden potential in the historically discarded MRI data that is recorded in start-up period of scans.
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Schulich WesternU @schulichmeddent.bsky.social · 13/11/2025
Researchers at @westernu.ca have unlocked surprising power in the first seconds of a functional MRI scan. Short, deliberate pauses boost the signal that follows – producing sharper, more responsive images of brain activity. Published today in @natmethods.nature.com.
schulich.uwo.ca
Signal in the silence: Researchers uncover hidden potential in discarded MRI data - Schulich School of Medicine & Dentistry - Western University
A new technique is transforming how scientists use fMRI to study the brain.
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Reposted by Renil Mathew
Ravi Menon @northernthrux.bsky.social · 13/11/2025
If the community wants, we have XA60 and VE12U versions we can make available as a C2P for Siemens scanners. And we have a Paravision 360 v3.6 available for Bruker. The processing code is equally simple and is posted with the paper.
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Reposted by Renil Mathew
Ravi Menon @northernthrux.bsky.social · 13/11/2025
This article in The Transmitter covering our paper may be one of the best scientific content headlines of all time. www.thetransmitter.org/fmri/timing-...
thetransmitter.org
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
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Renil Mathew @renilmathew.bsky.social · 13/11/2025
Super excited about my first first-author paper, now out in @natmethods.nature.com 🥳
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Renil Mathew @renilmathew.bsky.social · 13/11/2025
Excited to share my first first-author paper in Nature Methods!🤩 A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments. www.nature.com/articles/s41...
nature.com
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods
Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...
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Schulich WesternU @schulichmeddent.bsky.social · 31/10/2025
On this day in 1920, Dr. Frederick Banting woke at 2 a.m. in #LdnOnt and jotted down a 25-word idea — setting in motion the discovery of insulin. 105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment. Learn more: www.uwo.ca/projects/her...
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Renil Mathew @renilmathew.bsky.social · 11/10/2025
Thrilled to share that the central work of my PhD will be published soon.😬
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Ravi Menon @northernthrux.bsky.social · 22/09/2025
A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks. direct.mit.edu/imag/article...
direct.mit.edu
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
Abstract. Mouse functional magnetic resonance imaging (fMRI) studies contribute significantly to basic fundamental and translational neuroscience research. Performing fMRI in awake mice could facilita...
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The Transmitter @thetransmitter.bsky.social · 25/06/2025
ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis. www.thetransmitter.org/human-neurot...
thetransmitter.org
fMRI can do more than you think
Advances in brain imaging technology provide new and different information about the brain.
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Andrew Pruszynski @andpru.bsky.social · 13/06/2025
We're excited share our perspective on whether you only use 10 bits/s of your brain.
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The Transmitter @thetransmitter.bsky.social · 02/06/2025
Human neuroscience research has largely overlooked the mesoscale, which bridges cells and brain areas. But new advances in fMRI technology are changing that, writes Laurentius Huber @layerfmri.bsky.social. #neuroskyence www.thetransmitter.org/future-of-fm...
thetransmitter.org
Imaging cortical layers to understand brain as network organ
This spatial scale, bridging cells and brain areas, has been overlooked in human brain research. But advances in fMRI technology are changing that.
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Renil Mathew @renilmathew.bsky.social · 28/05/2025
New revised preprint on the SASS paradigm now with extensive human experiments, showing its broader applicability—check it out!
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Ravi Menon @northernthrux.bsky.social · 05/05/2025
Western University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...
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Ravi Menon @northernthrux.bsky.social · 06/03/2025
If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.
uwo.ca
Western Postdoctoral Fellowship Program
Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.
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Ravi Menon @northernthrux.bsky.social · 03/12/2024
Since I have a new set of followers here, I thought I'd repost a link to our preprint that describes a new event related fMRI method that allows 2x the SNR of normal fMRI and beautiful single unit and EEG recordings, dead silence to present auditory stimuli etc. 1/2 www.biorxiv.org/content/10.1...
biorxiv.org
Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI
Functional MRI (fMRI) studies discard the initial volumes acquired during the approach of the magnetization to its steady-state value. Here, we leverage the substantially higher temporal signal-to-noi...
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