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Renal Pathology Society (RPS)

@renalpathsociety.bsky.social
154 followers 78 following 40 posts

BlueSky account of the Renal Pathology Society (RPS) #renalpath www.renalpathsoc.org

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Reposted by Renal Pathology Society (RPS)
American Journal of Kidney Diseases @ajkd.bsky.social · 21/09/2026
Prevalence Estimates of Predicted Pathogenic COL4A3-COL4A5 Variants in the Chinese Population and Its Implications for Clinical Practice bit.ly/43r4RQY
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Reposted by Renal Pathology Society (RPS)
American Journal of Kidney Diseases @ajkd.bsky.social · 22/09/2026
Complement in Kidney Disease: Core Curriculum 2026 bit.ly/4cTLy85
Overview of complement effects. Complement activation generates multiple effector molecules. C3 fragments (C3b, iC3b, C3d) are covalently bound to target cell membranes. C3b on the surface of target cells can form C3 convertase, leading to further complement activation at that site. Both iC3b and C3d are ligands for 4 complement receptors (CR1-4) expressed by leukocytes and dendritic cells. C3a and C5a are soluble peptides that are released during the cleavage of C3 and C5, respectively. They are ligands for receptors expressed by leukocytes and parenchymal cells. They induce multiple downstream functions, including the chemotaxis and activation of myeloid cells to sites of inflammation. Activation can also generate C5b-9 multimers on cell membranes. C5b-9 forms a pore through the outer membrane. In sublytic quantities this can cause cell activation. If sufficient C5b-9 is formed it can cause osmotic lysis of the cell. Created with BioRender.
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Reposted by Renal Pathology Society (RPS)
Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 03/12/2024
Excellent PKD gross photo taken by @clilleymd.bsky.social #nephology #pathsky #renalpath
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Reposted by Renal Pathology Society (RPS)
Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 17/01/2025
Lupus membranous is often the most membranous membranous (most membranous-sy?) #renalpath #nephsky #pathsky
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Reposted by Renal Pathology Society (RPS)
Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 01/10/2026
Interesting report. But all 4 donors had overt proteinuria at the time of organ allocation. Is it standard procedure to ignore that in deceased kidney donation? Tapping a transplantologist @georginairish.bsky.social @nymurakami.bsky.social #NephSky
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 24/09/2026
Pt with myelofibrosis, NR proteinuria, progressive CKD. Hypercellular glomeruli + intracapillary megakaryocytes, + mesangial sclerosis, +chronic microangiopathic changes c/w MPN-related glomerulopathy. Also renal extramedullary hematopeosis. IHC is CD61 #renalpath #pathsky #nephsky
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kireports.bsky.social @kireports.bsky.social · 18/09/2026
#Clinical and #Pathological Characteristics of Patients With Antineutrophil Cytoplasmic Antibody-Associated #ANCA Vasculitis With #RenalArteritis #VisualAbstract by Akshaya Jayachandran www.kireports.org/article/S2468-024…
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 27/01/2025
Can we please stop using the term "apple green" for amyloid polarization with congo red. It's often yellow/orange and the green is typically not apple colored. I have heard folks not want to diagnose amyloid b/c it wasn't green. pubmed.ncbi.nlm.nih.gov/26177276/ #pathsky #nephrology #renalpath
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 26/01/2025
Younger pt who presented with history of diarrhea and AKI without significant PMHx and no medication use. Bx demonstrated Granulomatous interstitial nephritis. Colon biopsies with chronic active colitis with granulomas c/w with crohn disease --> GIN (no mesalamine) #renalpath #pathsky #nephsky
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Reposted by Renal Pathology Society (RPS)
American Journal of Kidney Diseases @ajkd.bsky.social · 26/01/2025
#RenalPath Bile nephrosis with intratubular yellow-green granular casts. Acute tubular injury and intratubular cellular debris are present (hematoxylin and eosin stain). bit.ly/4fULzHE (FREE)
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Reposted by Renal Pathology Society (RPS)
Grace Choung, MD 박영이 @gracechoung.bsky.social · 26/01/2025
Elderly patient with DM ,HTN, CAD p/w SOB, edema, AKI, & oliguria. Low C3. UA 3+ prot,wbcs+rbcs. Urine Cx +ecoli. Acute bacterial infection-related GN-exudative (lots of neutrophils) and starry sky C3 (IF) + hump-like subepithelial deposits (EM) t.co/q3QEy4ZnQP #renalpath #PathSky #NephSky #MedSky
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Reposted by Renal Pathology Society (RPS)
Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 11/11/2024
Smiling glomerulus to brighten your day. #pathology #renalpath #nephropathy #nephropath
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Reposted by Renal Pathology Society (RPS)
Canadian Society of Nephrology @csnscn.bsky.social · 18/09/2026
🗣️ Our next session is titled “Inside the Onco-Nephrology Tumor Board: Navigating Complex Cases”. 🧭 📸 Pictured: Kim Cheema, Elena Barbir, Lynn Cornell, and Vishal Kukreti, Megan Borkum, Mark Canney, and John Gill . #CSNSCN #Nephrology #Kidneys #CSN
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Reposted by Renal Pathology Society (RPS)
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 18/09/2026
Dr @lynncornell.bsky.social shows this classic bird’s eye appearance of the kidney biopsy in IgG4 interstitial nephritis Read here www.sciencedirect.com/science/arti... for more in @kireports.bsky.social #CSNHomecoming @csnscn.bsky.social
Birds Eye appearance of kidney - seen in IgG4 TIN
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Reposted by Renal Pathology Society (RPS)
American Journal of Kidney Diseases @ajkd.bsky.social · 18/09/2026
Allocation of Kidney Allografts From Donors With Kidney Donor Profile Index <35% and the Impact of Kidney Donor Profile Index Revisions on Access to Transplantation for Children bit.ly/42iKSDu (OPEN ACCESS) @super_jrub
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 04/09/2026
Yale Pathology is accepting applications for 1-year combined Renal & GU Pathology fellowship starting July 1, 2027 & 2028. See image below and link for more info. Apply: path.education@mailman.yale.edu medicine.yale.edu/pathology/tr... #renalpath #GU #fellowship #pathysky @yalepathology.bsky.social
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 23/11/2024
CKD, proteinuria, Crohn's disease. KBx w/focally granulomatous tubulointerstitial nephritis and IgAN. Common findings in IBD patients (pubmed.ncbi.nlm.nih.gov/38344742/). Pt on TNFa inhibitor (pubmed.ncbi.nlm.nih.gov/36706240/) also reported IgAN/TIN associations. #renalpath #pathsky #nephrology.
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Reposted by Renal Pathology Society (RPS)
Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 15/03/2026
The Armanni-Ebstein (not Epstein😅) lesion in a nondiabetic patient The glycosuria from flozination can cause these, very interesting phenomenon www.kidney-international.org/article/S008... in Kidney International #RenalPath
Figure 1 Light and electron microscopy reveal epithelial cell vacuolation in acute tubular injury. (a) Light microscopy shows focal acute tubular injury at the corticomedullary junction, with significant swelling of tubular epithelial cells caused by optically transparent vacuoles. Hematoxylin and eosin staining. Bar = 50 μm. (b) The vacuoles contain periodic acid–Schiff–positive material. Bar = 50 μm. (c) Electron microscopy of paraffin-fixed tissue reveals the outline of tubular epithelial cell membranes, partial cell nuclei, and degenerated organelles, with obvious intracellular cavitation. Bar = 10 μm. To optimize viewing of this image, please see the online version of this article at www.kidney-international.org.
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 28/05/2026
Renal Pathology Society's Case in Focus Middle-aged male with HTN & CKD presented with nephrotic range proteinuria Rita Santarsiere & Nicolas Kozakowski English: renalpathsoc.org/page-1075904 Links to translations (Spanish, Portuguese, French, Chinese) in post below #renalpath #pathsky #nephsky
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 21/07/2026
Haven't seen one of these in a while. Example of atheroembolism in a older pt with subacute kidney injury and peripheral vascular disease. Cholesterol clefts and giant cells filling the arterial lumen. #renalpath #pathsky #nephsky
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Kidney International @kidneyint.bsky.social · 17/08/2026
Review Anti–glomerular basement membrane disease: variant forms and underlying mechanisms doi.org/10.1016/j.kint.2026.03.029 #NephSky #MedSky #RenalPath #KidneyPath #AntiGBM #glomerulonephritis
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Kidney International @kidneyint.bsky.social · 17/08/2026
Clinical Journey in Translational Medicine Monitoring anti-nephrin antibodies in the management of recurrent diffuse podocytopathy doi.org/10.1016/j.kint.2026.06.013 #NephSky #MedSky #FSGS #renalpath #kidneypath #transplantation @columbiamed.bsky.social @mgbresearch.bsky.social
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Kidney International @kidneyint.bsky.social · 26/08/2026
Nephrology Image Obstructive renal Candida fungus balls in an SGLT2-inhibitor user doi.org/10.1016/j.kint.2026.03.025 #NephSky #MedSky #renalpath #kidneypath #SGLT2i
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Grace Choung, MD 박영이 @gracechoung.bsky.social · 12/09/2026
Complement in Kidney Disease: Core Curriculum 2026 - American Journal of Kidney Diseases www.ajkd.org/article/S027...
ajkd.org
Complement in Kidney Disease: Core Curriculum 2026
The complement cascade is part of the innate immune system, and it provides an important line of defense against infections. Inappropriate or excessive activation of this system, however, is also a dr...
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Reposted by Renal Pathology Society (RPS)
Grace Choung, MD 박영이 @gracechoung.bsky.social · 14/09/2026
Pathological Diagnostic Criteria for Thrombotic Microangiopathy in the Renal Allograft: Lessons Learned During the Banff Working Group Consensus Process - Kidney Medicine www.kidneymedicinejournal.org/article/S259...
kidneymedicinejournal.org
Pathological Diagnostic Criteria for Thrombotic Microangiopathy in the Renal Allograft: Lessons Learned During the Banff Working Group Consensus Process
Given the challenges in diagnosing transplant thrombotic microangiopathy (Tx-TMA) highlighted in previous publications, the objectives were to: 1- summarize new diagnostic challenges of Tx-TMA; 2- exp...
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Reposted by Renal Pathology Society (RPS)
Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 09/09/2026
Well developed example of medullary angiitis (pubmed.ncbi.nlm.nih.gov/23079202/) in a case of MPO-ANCA associated GN. Neutrophils and hemorrhage in the medulla. Also plenty of active crescents in this case. #renalpath #pathsky #nephsky
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Grace Choung, MD 박영이 @gracechoung.bsky.social · 15/09/2026
The ultrastructure of a cast: the art and science of renal tubular pathology: Ultrastructural Pathology: Vol 50 , No 3 - Get Access www.tandfonline.com/doi/full/10.... #EM #ultrastructure #renalpath #pathsky
tandfonline.com
The ultrastructure of a cast: the art and science of renal tubular pathology
Renal tubular casts are cylindrical structures formed primarily in the distal convoluted tubule or collecting tubule. They are composed of materials filling the tubular lumen and molding along its ...
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American Journal of Kidney Diseases @ajkd.bsky.social · 12/09/2026
Association of Histological Features of Cortical and Medullary Peritubular Capillaries With Progressive CKD bit.ly/4gbL1z7 (OPEN ACCESS)
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American Journal of Kidney Diseases @ajkd.bsky.social · 13/09/2026
12-year Follow-up of a Family With CKD Caused by an mtDNA Variant bit.ly/4A2TxcJ
Pedigree of this family and renal pathology of three siblings. A. Pedigree demonstrates a maternal inheritance pattern of this family. Black denotes renal disease. Proband is denoted with arrow (III.18); A male patient with intellectual disability is denoted in dark gray (III.3); another female patient with muteness is denoted in light gray (III.5). Percentages indicate heteroplasmy level of the mutation in blood. B1-D5, B1-D5. Light microscopic findings of the elder brother(III.13), eldest sister(III.14), and second sister (III.16). The first column (B1-B5), second column (C1-C5) and third column (D1-D5) represent the renal pathology of the elder brother (III.13), eldest sister (III.14), and second sister (III.16), respectively. B1-D1: Whole slide image of kidney biopsy tissues from three siblings (Masson’s trichrome). B2-D2: All three cases showed focal tubular atrophy and interstitial fibrosis with mild (B2) to severe (C2 and D2) inflammatory cells infiltration (yellow star).
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American Journal of Kidney Diseases @ajkd.bsky.social · 13/09/2026
Progressive Kidney Dysfunction and Ocular Clues: A Quiz bit.ly/4xgJoXk (FREE)
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 04/09/2026
Yale Pathology is accepting applications for 1-year combined Renal & GU Pathology fellowship starting July 1, 2027 & 2028. See image below and link for more info. Apply: path.education@mailman.yale.edu medicine.yale.edu/pathology/tr... #renalpath #GU #fellowship #pathysky @yalepathology.bsky.social
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Kidney International @kidneyint.bsky.social · 03/09/2026
Improving the Histologic Classification of Advanced Diabetic Nephropathy Based on the Transformative Research in #DiabeticNephropathy (TRIDENT) Findings doi.org/10.1016/j.kint.2026.07.028 #NephSky #MedSky #OpenAccess @upenn.edu @cedarssinaihsu.bsky.social @yale.edu #DiabeticNephropathy #PathSky
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 17/08/2026
2026 RPS-GlomCon Webinar Series Apolipoprotein 1-Mediated Kidney Disease Sunday, August 30, 2026 8:00 - 9:00 am Pacific Time Jon Wilson, MD @arkanalabs.bsky.social For more info: renalpathsoc.org/event-6719284 #renalpath @glomcon.org #pathsky #nephsky
renalpathsoc.org
Renal Pathology Society - 2026 RPS-GlomCon Webinar Series: Apolipoprotein 1-Mediated Kidney Disease
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 18/08/2026
Applications for the 2027 USCAP Global Partner Travel Award are now open. Application Deadline: Tuesday, August 27, 2026 More info: uscap.org/global-partn... #renalpath #pathsky
uscap.org
Global Partner Travel Award - USCAP
Global Partner Travel Award APPLICATIONS NOW OPEN Deadline: Tuesday, August 27, 2026 APPLY NOW Applications are now open for the Global Partner Travel Award for our 2027 Annual Meeting in Vancouver, B...
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Reposted by Renal Pathology Society (RPS)
Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 21/08/2026
Nice example of multi-cystic renal dysplasia. Metaplastic cartilage, disordered tubules, tubular cysts, and scattered immature appearing tubules with fibromuscular collarets. #renalpath #nephsky #pathsky
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Kidney International @kidneyint.bsky.social · 10/08/2026
Early Acute T Cell-Mediated Rejection and Kidney Allograft Outcomes doi.org/10.1016/j.kint.2026.06.042 #NephSky #MedSky #pathsky #OpenAccess @uzleuven.bsky.social @inserm.fr
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Juan Carlos Q Vélez, MD @juancarlosqvelez.bsky.social · 12/08/2026
Love the key inclusion of #UrineMicroscopy to identify glomerular hematuria at the top of the algorithm for hematuria. Best way to avoid unnecessary invasive (cystoscopy) and costly (CT) urological testing #UrinarySediment #NephSky
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Kidney International @kidneyint.bsky.social · 11/08/2026
Nephrology Image Disappearing glomeruli: loss of linear IgG in anti-GBM nephritis #MedSky #NephSky
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Kidney International @kidneyint.bsky.social · 12/08/2026
Commentary Renal biopsy in patients with diabetes: still going strong after all these years doi.org/10.1016/j.kint.2026.05.003 Original article: doi.org/10.1016/j.kint.2026.03.015 #MedSky #NephSky #PathSky #DiabeticNephropathy #KidneyBiopsy #NonDiabeticKidneyDisease #NDKD #RenalPath
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Grace Choung, MD 박영이 @gracechoung.bsky.social · 22/08/2026
Rethinking Proteinuria During VEGF-Axis Therapy: Toward a Biopsy-Informed Approach - Kidney International Reports www.kireports.org/article/S246...
kireports.org
Rethinking Proteinuria During VEGF-Axis Therapy: Toward a Biopsy-Informed Approach
VEGF-axis inhibitors, including VEGF ligand-directed agents such as bevacizumab and VEGF receptor-targeted tyrosine kinase inhibitors (TKIs), are integral to the treatment of advanced solid tumors. Th...
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Alexander Woywodt @pwoywodt.bsky.social · 22/08/2026
B- and plasma cell-targeting therapies for podocytopathies: state of the art and the New Gaslini Protocol academic.oup.com/ckj/article/...
academic.oup.com
B- and plasma cell-targeting therapies for podocytopathies: state of the art and the New Gaslini Protocol
Abstract. Podocytopathies, including minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), and idiopathic nephrotic syndrome (INS), are
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ISNkidneycare @theisn.org · 21/08/2026
📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Antinephrin Antibodies in IgAN: Toward a Phenotype-Driven, Personalized Approach www.kireports.org/article/S2468-024…
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Grace Choung, MD 박영이 @gracechoung.bsky.social · 22/08/2026
Targeting the BAFF and APRIL Pathway in IgA Nephropathy: From Disease Pathogenesis to Clinical Trial Evidence - Kidney International Reports www.kireports.org/article/S246...
kireports.org
Targeting the BAFF and APRIL Pathway in IgA Nephropathy: From Disease Pathogenesis to Clinical Trial Evidence
Immunoglobulin A nephropathy (IgAN) is an immune-mediated glomerular disease driven by dysregulated mucosal B-cell immunity, leading to the overproduction of galactose-deficient IgA1 (Gd-IgA1) and the...
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 18/08/2026
Applications for the 2027 USCAP Global Partner Travel Award are now open. Application Deadline: Tuesday, August 27, 2026 More info: uscap.org/global-partn... #renalpath #pathsky
uscap.org
Global Partner Travel Award - USCAP
Global Partner Travel Award APPLICATIONS NOW OPEN Deadline: Tuesday, August 27, 2026 APPLY NOW Applications are now open for the Global Partner Travel Award for our 2027 Annual Meeting in Vancouver, B...
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Reposted by Renal Pathology Society (RPS)
kireports.bsky.social @kireports.bsky.social · 14/08/2026
Kidney #Allograft Outcomes in #Borderline and T Cell-Mediated Rejection #TCMR With Microvascular Inflammation #VisualAbstract by Brian Rifkin www.kireports.org/article/S2468-024…
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aspneph.bsky.social @aspneph.bsky.social · 14/08/2026
Clinical and genetic characteristics of hypoparathyroidism, deafness, and renal dysplasia syndrome in a chronic kidney disease cohort link.springer.com/article/10.1... #PedNeph #Nephrology
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Reposted by Renal Pathology Society (RPS)
Grace Choung, MD 박영이 @gracechoung.bsky.social · 15/08/2026
12-year Follow-up of a Family With CKD Caused by an mtDNA Variant - American Journal of Kidney Diseases www.ajkd.org/article/S027...
ajkd.org
12-year Follow-up of a Family With CKD Caused by an mtDNA Variant
While a few studies have investigated renal manifestations associated with mitochondrial DNA (mtDNA) mutations, detailed renal histopathological changes and long-term outcomes remain poorly characteri...
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Jonathan Zuckerman MD PhD @jzrenalpath.bsky.social · 17/08/2026
Fibrillary GN with linear staining potentially mimicking anti-GBM. Mesangial staining + mesangial expansion by silver weak material not typical for anti-GBM. Also only focal crescents. fibrils infiltrating GBM on EM. #renalpath #pathsky #nephsky
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Renal Pathology Society (RPS) @renalpathsociety.bsky.social · 17/08/2026
2026 RPS-GlomCon Webinar Series Apolipoprotein 1-Mediated Kidney Disease Sunday, August 30, 2026 8:00 - 9:00 am Pacific Time Jon Wilson, MD @arkanalabs.bsky.social For more info: renalpathsoc.org/event-6719284 #renalpath @glomcon.org #pathsky #nephsky
renalpathsoc.org
Renal Pathology Society - 2026 RPS-GlomCon Webinar Series: Apolipoprotein 1-Mediated Kidney Disease
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