Sign in

R. Brian Roome

@rbrianroome.bsky.social
87 followers 84 following 9 posts

Research associate, Kania lab, IRCM. Investigating formation and function of spinal cord sensory and ascending circuits. Avid balcony gardener and amateur musician. Views are my own.

PostsRepliesMedia
Reposted by R. Brian Roome
Estelle Renaux @estellerenaux.bsky.social · 03/10/2026
Happy to share the first paper from my postdoc @sagnera.bsky.social in collaboration with the brilliant PhD students @laiacaudet.bsky.social and @archimistry.bsky.social. In here, we investigate the role of miRNAs in the temporal patterning of the spinal cord. 🔗 www.biorxiv.org/content/10.6...
71911
R. Brian Roome @rbrianroome.bsky.social · 22/08/2026
With *light* bias, this is a top tier postdoc opportunity with a wonderfully supportive supervisor!
110
Reposted by R. Brian Roome
Ariel Levine @ariellevine.bsky.social · 18/08/2026
We have 2 postdoc positions available to study spinal mechanisms of motor control. Postdoc 1 will focus on how specific spinal cell types shape neural activity www.levine-lab.org jobs.smartrecruiters.com/UniversityHe...
jobs.smartrecruiters.com
Postdoctoral Researcher, Spinal Mechanisms of Motor Control - Neural Activity
Company Description: The University Health Network, where “above all else the needs of patients come first”, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Canc...
01411
R. Brian Roome @rbrianroome.bsky.social · 26/06/2026
If it's that easy to be a radical, may as well shoot for the stars. Domestic labor is unpaid labor / wage theft.
150
Reposted by R. Brian Roome
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 16/06/2026
Deep Cellular and Spatial Profiling of the Mouse Spinal Cord Reveals Sex-Specific Neuron Types and the Ascending Projection Neuron Repertoire www.biorxiv.org/content/10.64898/20…
041
Reposted by R. Brian Roome
Wei-Chung Allen Lee @darbly.bsky.social · 09/06/2026
Now published - the #BANC! A full central nervous system (CNS) connectome of a limbed animal at single-synapse resolution, enabling us to follow sensory-motor arcs and understand how the CNS controls the body. rdcu.be/fncjS. #neuroscience. Video by @quorumetrix.bsky.social 1/18
214984
Reposted by R. Brian Roome
Ariel Levine @ariellevine.bsky.social · 21/04/2026
📣 Exciting news: my lab is moving to the Krembil Institute at the University of Toronto’s University Health Network in Fall 2026. We’ll be recruiting for all roles, so reach out if you’re interesting in joining us to study spinal circuits for sensorimotor control www.levine-lab.org
levine-lab.org
Home | Levine Lab
1714934
Reposted by R. Brian Roome
Sarah Ross @sarahross1.bsky.social · 17/04/2026
We’re hiring! The University of Pittsburgh is recruiting a tenure-track faculty member in pain research to join the Department of Neurobiology and the Pittsburgh Center for Pain Research—an outstanding and highly collaborative community. Please share. More here: cfopitt.taleo.net/careersectio...
13540
Reposted by R. Brian Roome
Fabricio Nicola @fabricionicola.bsky.social · 14/03/2026
Understanding these modular substrates may help reveal how the nervous system builds complex actions and open new avenues for restoring coordinated movement after neurological injury. You can read the full story here: www.biorxiv.org/content/10.6...
biorxiv.org
0112
Reposted by R. Brian Roome
Ariel Levine @ariellevine.bsky.social · 04/02/2026
Want to come do a postdoc with us? We’re interested in how sensorimotor function is carried out by the cells and circuits of the spinal cord. We have an awesome team, lots of cool techniques, and we’re open to new ideas/approaches/connections. Get in touch!
02420
Reposted by R. Brian Roome
Stand Up for Science! @standupforscience.net · 24/01/2026
This is Alex Pretti. This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA. Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE. #ScientistsAgainstICE
Alex Pretti, wearing a green sweater with his VA badge on.
271635762
Reposted by R. Brian Roome
Stand Up for Science! @standupforscience.net · 24/01/2026
America is in dangerous territory. The combination of a masked federal paramilitary force being used against civilians, the intentional spread of extremist ideology, and the censorship and use of “science” by the state to harm specific groups of people has never ended well. #ScientistsAgainstICE
419560
Reposted by R. Brian Roome
Stand Up for Science! @standupforscience.net · 19/01/2026
ICE’s actions tear families apart, intimidate communities, & undermine the conditions that make education, research, healthcare, & public trust possible. We’re calling on scientists to join the general anti-ICE strike in Minnesota on January 23rd.
Red protest-style graphic with bold white text reading “Scientists Against ICE.” Below, rows of black human silhouettes stand holding hands. Centered is the Stand Up for Science logo, followed by text: “Calls for a General Strike Jan 23, 2026, Minnesota.” Black starburst shapes frame the sides. Bottom text reads: “Mobilize the fight for science and democracy.”
8444218
Reposted by R. Brian Roome
Marcin Szczot @szczotml.bsky.social · 14/12/2025
Not all pain is created equal: stepping on a nail feels different from a stomachache. We know there are many nociceptor types, but a key question remains: how is mechanical pain encoded across the body by those sensory neurons? Our new work helps answer this. 1/8 www.biorxiv.org/content/10.6...
biorxiv.org
Hierarchical organization of mechano-nociceptive pathways revealed by activity labeling
Noxious mechanical stimuli give rise to distinct percepts, from sharp cutaneous pain to diffuse visceral discomfort, yet the nociceptor ensembles that underlie these differences remain poorly defined....
22414
Reposted by R. Brian Roome
Ted Price @tedpricethepainguy.bsky.social · 07/11/2025
The BIG DRG paper is now up on @biorxiv-neursci.bsky.social www.biorxiv.org/content/10.1... so many people worked so hard to make this happen. Props to the whole PRECISION Human Pain Network.
biorxiv.org
A Reference Atlas of the Human Dorsal Root Ganglion
Somatosensory perception largely emerges from diverse peripheral sensory neurons whose cell bodies reside in dorsal root ganglia (DRG). Damage or dysfunction of DRG neurons is a major cause of chronic...
12713
Reposted by R. Brian Roome
BeatoLab @beatolab.bsky.social · 02/09/2025
An absolutely lovely paper, if I may say so... Joint effort from @tuanbuilab.bsky.social, Turgay Akay, and the Beatostone lab, aka Rob Brownstone's lab and mine
2132
Reposted by R. Brian Roome
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 01/09/2025
A Neural Circuit for Modular Gating of Organ Somatosensation www.biorxiv.org/content/10.1101/202…
041
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
With the two orthogonal factors – birth time and and a gradient of Zic genes – we are able to describe the mechanisms of cellular diversity and structure which come together to produce the dorsal horn! Message me and let’s start figuring out what this diversity means for spinal cord physiology! 7/7
030
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
Inhibitory neurons from the same family vary by Zic expression: Rorb neurons express lots of Zic and Satb2 neurons express almost none, and this directs their laminar position. Loss of Zics = drop of Rorb, increase in Satb2 neurons, and so on for each family. 6/n
120
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
Well, time isn’t everything! We find a progenitor gradient of the Zic genes which are imprinted onto dorsal horn neurons as they’re born. 5/n
110
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
Excitatory neurons are particularly crucial – only when you lose excitatory neurons does laminar structure collapse. Inhibitory neurons also are born in a sequence of families though – but not quite so neatly. Despite that, they are way more diverse. So what else is going on? 4/n
110
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
By birthdating families of dorsal horn neurons, we show that the order excitatory neurons are born in is the order of their laminae! Here, time is structure! 3/n
110
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
We show a new embryonic single-cell spinal cord atlas, hugely expanding the types of known neurons. We see the usual crowd, plus large families of dorsal excitatory (dILB) and inhibitory (dILA) neurons which match the families described postnatally. dILB3 = Grp family, dILA5 = Pdyn family, etc. 2/n
110
R. Brian Roome @rbrianroome.bsky.social · 17/03/2025
Check out my postdoc work at Ariel Levine’s lab, hot and fresh, describing how you build a dorsal horn! www.biorxiv.org/content/10.1...
14213