Ranier Gutierrez @raniergutierrez.bsky.social · 18/07/2026The Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructure doi.org/10.7554/eLif...doi.orgThe Crunchometer, a low-cost, open-source acoustic analysis of feeding microstructureMaking the moment-to-moment dynamics of solid-food intake measurable in any laboratory enables researchers to map the brain circuits that control appetite and accelerate the development of treatments ... 031
Ranier Gutierrez @raniergutierrez.bsky.social · 22/06/2026The Crunchometer software is available on GitHub (github.com/RanierLabNeuro…). Enjoy it!!!github.com 000
Ranier Gutierrez @raniergutierrez.bsky.social · 22/06/2026youtu.be/cubBnfOoGy8?...youtu.beTutorial of The Crunchometer SoftwareYouTube video by Laboratory Neurobiology of Appetite Cinvestav 100
Ranier Gutierrez @raniergutierrez.bsky.social · 22/06/2026youtu.be/NjGIA0OX1ms?...youtu.beEngineering the CrunchometerYouTube video by Ranier Gutierrez 100
Ranier Gutierrez @raniergutierrez.bsky.social · 22/06/2026The Crunchometer it is published now in eLife doi.org/10.7554/eLif...doi.orgThe Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure 153
Ranier Gutierrez @raniergutierrez.bsky.social · 03/11/2025The Crunchometer is a low-cost, open-source technology that uses bite sound to democratize the microstructural analysis of feeding bouts on solid food: 🧪 The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure. doi.org/10.7554/eLif...doi.org 051
Reposted by Ranier GutierrezbioRxiv Neuroscience @biorxiv-neursci.bsky.social · 31/07/2025The Crunchometer: A Low-Cost, Open-Source Acoustic Analysis of Feeding Microstructure www.biorxiv.org/content/10.1101/202… 021
Ranier Gutierrez @raniergutierrez.bsky.social · 26/06/2025A new paper from the laboratory Neurobiology of Appetite at Cinvestav. We introduced the OptoDrive! To record and optogenetically stimulate the brain of freely moving mice www.eneuro.org/content/12/6...eneuro.orgAutomatic OptoDrive for Extracellular Recordings and Optogenetic Stimulation in Freely Moving MiceExtracellular recordings in freely moving mice, especially those with movable electrodes (microdrives), are crucial for understanding brain function. However, existing microdrives are often heavy, exp... 000
Ranier Gutierrez @raniergutierrez.bsky.social · 25/06/2025A new paper out of Laboratory Neurobiology of Appetite! Developing an automatic algorithm to detect head weaving stereotypes induced by DA appetite suppressants journals.plos.org/plosone/arti...journals.plos.orgSex-specific effects of appetite suppressants on stereotypy in ratsThis study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy. Employing video recor... 000
Reposted by Ranier GutierrezMark Rossi @markrossi.bsky.social · 10/06/2025A nice write up about the new work coming out of the Rutgers Center for NeuroMetabolism www.rutgers.edu/news/two-rut...rutgers.eduTwo Rutgers Teams Trace Brain Circuits That Tell Us When to Eat – and When to StopBack-to-back studies map complementary hunger and satiety pathways, offering clues to refine weight-loss drugs. 142
Reposted by Ranier GutierrezGiuseppe Gangarossa 🧠👨🔬🏳️🌈🇪🇺 @peppeganga.bsky.social · 16/05/2025Excited to share our latest story: "The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events" 🎉. Big congrats to 1st author Oriane Onimus 💪 🥳 & many thanks to all those involved 🙏🙏. www.biorxiv.org/content/10.1...biorxiv.orgThe gut-brain vagal axis governs mesolimbic dopamine dynamics and reward eventsReward-related processes have traditionally been ascribed to neural circuits centered on the dopamine (DA) system. While exteroceptive stimuli, such as food and drugs of abuse, are well-established ac... 2335
Reposted by Ranier GutierrezKara Marshall @karalmarshall.bsky.social · 03/05/2025Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cigyoutu.beKara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25YouTube video by Steve Lawson 1727980
Reposted by Ranier GutierrezMark Rossi @markrossi.bsky.social · 12/04/2025The new Rutgers Center for NeuroMetabolism is officially hiring faculty at all levels! Come be my colleague! jobs.rutgers.edu/postings/248...jobs.rutgers.eduAssistant/Associate/Full ProfessorThe newly launched Rutgers Center for NeuroMetabolism (CNM), in collaboration with the Child Health Institute of New Jersey (CHINJ), the Department of Neuroscience and Cell Biology (NCB), and the Rutg... 01210
Ranier Gutierrez @raniergutierrez.bsky.social · 27/03/2025open.spotify.com/episode/3ISr...open.spotify.comEpisode 40: An Appetite for DiscoveryThe Gastronauts Podcast · Episode 010
Ranier Gutierrez @raniergutierrez.bsky.social · 19/02/2025www.growkudos.com/publications...growkudos.comSomething in the Way Mice Lick: Revealing the Secrets of Brain Reward CircuitsThis research delves into how a specific type of brain cell – the D2 neuron, named for a particular docking station (receptor) for the “feel-good” neurotransmitter dopamine – controls both our sense o... 000
Ranier Gutierrez @raniergutierrez.bsky.social · 14/02/2025We used DeepLabCut to study head-weaving stereotypy induced by appetite suppressants 000
Ranier Gutierrez @raniergutierrez.bsky.social · 14/02/2025New preprint from the lab, here we study head waving stereotypy induced by some appetite suppressants www.biorxiv.org/content/10.1...biorxiv.orgSex-specific effects of appetite suppressants and stereotypy in ratsThis study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy. Employing video recor... 141
Ranier Gutierrez @raniergutierrez.bsky.social · 07/02/2025New paper from the lab!!! D2-expressing neurons in accumbens is rewarding but paradoxically it stops licking! journals.plos.org/plosone/arti...journals.plos.orgNucleus accumbens D2-expressing neurons: Balancing reward and licking disruption through rhythmic optogenetic stimulationNucleus accumbens (NAc) dopamine D1 receptor-expressing neurons are known to be critical for processing reward and regulating food intake. However, the role of D2-expressing neurons in this nucleus re... 151
Reposted by Ranier GutierrezCarsen Stringer @computingnature.bsky.social · 12/01/2025What if… spontaneous neural activity 🧠 reflects the baseline rumblings of a brainwide dynamical system initialized for learning? We find that the rumblings have macroscopic properties like those emerging from linear symmetric, critical systems 🧵 #neuroscience #neuroAI www.biorxiv.org/content/10.1... 931083
Reposted by Ranier GutierrezAli D. Güler @aguler.bsky.social · 18/12/2024GLP-1 receptor agonists (GLP-1RAs) are transforming the treatment of obesity and diabetes (and more). Our recent pre-print examined next-gen small molecules mimicking GLP-1, using humanized mouse models to uncover how they interact with brain circuits driving food consumption. 1/15 2159
Reposted by Ranier GutierrezMike Krashes @mikekrashes.bsky.social · 03/12/2024New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5rdcu.beMolecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satietyNature Metabolism - Combining rabies-based connectomics with single-nucleus transcriptomics, the authors identify a neural circuit through which GLP-1 receptor agonists suppress appetite in mice. 24115
Reposted by Ranier GutierrezMike Krashes @mikekrashes.bsky.social · 02/12/2024A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S...authors.elsevier.com 1216
Reposted by Ranier GutierrezKevin Mitchell @wiringthebrain.bsky.social · 28/11/2024Order matters: neurons in the human brain fire in sequences that encode information www.nature.com/articles/d41...nature.comOrder matters: neurons in the human brain fire in sequences that encode informationA timing-based code for semantic knowledge in humans complements the established role of firing rates in neural coding. 211835
Ranier Gutierrez @raniergutierrez.bsky.social · 27/11/2024You are an expert on theory and practice! 020
Ranier Gutierrez @raniergutierrez.bsky.social · 27/11/2024I love this video, freely moving is the way 110
Ranier Gutierrez @raniergutierrez.bsky.social · 24/11/2024Optoception from a biohybrid graft. Really cool!!! 000
Ranier Gutierrez @raniergutierrez.bsky.social · 22/11/2024Neuronal ensembles in accumbens act as independent modules to process sucrose reward www.cell.com/cell-reports...cell.comThe flow of reward information through neuronal ensembles in the accumbensArroyo et al. show that NAcSh neuronal ensembles are distinct modules, each processing specific aspects of reward-guided behavior. These ensembles adapt during learning, forming different functional c... 030
Ranier Gutierrez @raniergutierrez.bsky.social · 22/11/2024Neuronal sequences are also present on gustatory cortices www.cell.com/iscience/ful...cell.comNeuronal Sequences and dynamic coding of water-sucrose categorization in rat gustatory corticesNeuroscience; Sensory neuroscience 120