Rachel Phillips @rachpips.bsky.social · 11/12/2025Glad you enjoyed, we had great fun writing it 😊 130
Rachel Phillips @rachpips.bsky.social · 26/11/2025To read their full article please see here: lnkd.in/epiZdzWBlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 001
Rachel Phillips @rachpips.bsky.social · 26/11/2025Don't miss out on the last webinar in our #AdverseEvent special series! November 27th 3-4pm (GMT) Louise Hill and Francesca Schiavone will be talking about their work on safety reporting in neonatal clinical trials To register for the webinar please complete the following: lnkd.in/ebMSPhdslnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 110
Reposted by Rachel PhillipsImperial Clinical Trials Unit @imperialctu.bsky.social · 31/10/2025Last night we celebrated our wonderful Director, Professor Victoria Cornelius at her inaugural lecture. She shared her academic journey highlighting the research she has been instrumental in where innovations in statistical methods have led to real changes in clinical trials and their outcomes. 111
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 24/10/2025📢 New blog post: www.statsci.co.uk/post/highlig... One of our NIHR pre-doctoral fellows Xiao Xuan Tan recently attended ISCB 2025 which was packed with cutting-edge statistical research & inspiring keynotes. Read all about her key highlights and takeaways from attending the conference herestatsci.co.ukHighlights and Reflections from ISCB 2025This summer, I had the opportunity to attend the 46th Annual Conference of the International Society for Clinical Biostatistics (ISCB) in Basel. It was an incredible week of learning and networking wi... 041
Reposted by Rachel PhillipsRichard Hooper @richardhooper.bsky.social · 24/10/2025📢 Interested in a PhD in clinical trials methodology? The Trials Methodology Research Partnership are advertising projects for PhDs starting Oct 2026, in statistics, health economics, epidemiology, social science, and more, hosted at one of 12 UK partner institutions. mrctmrpdtp.com/current-oppo...mrctmrpdtp.comCurrent OpportunitiesWe have an iCASE studentship available to start for the 2025/2026 academic year, and applications to our fifth round of recruitment to our DTP to start in October 2026 are now also open. Please see… 01213
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 13/10/2025📢 Chelsea&Westminster Hospital NHS Trust Research Dept. are looking for an enthusiastic & dedicated senior statistician with experience working on drug trials to lead on the statistical work for a small portfolio of sponsored studies. For details please see here: www.chelwest.nhs.uk/about-us/wor...chelwest.nhs.ukWork with us 012
Reposted by Rachel PhillipsRichard Hooper @richardhooper.bsky.social · 01/10/2025I'm doing a webinar in two weeks (15 Oct 1-2pm BST), part of NIHR Research Support Service's Methods Academy series, on the age-old question: should I do a stepped wedge trial? Free registration, details here: tinyurl.com/z6cjvce3 @nihr-rss.bsky.social @wiphcem.bsky.social @qmul-wiph.bsky.social 11315
Reposted by Rachel PhillipsImperial Clinical Trials Unit @imperialctu.bsky.social · 02/10/2025💬Got 5 mins? Help improve clinical trials by sharing your thoughts on health data collection. @anniestats.bsky.social a PhD researcher at Imperial has designed this survey with the help of her public involvement groups. 🔗 imperial.eu.qualtrics.com/jfe/form/SV_... #PPI #HealthEquity #ResearchVoicesimperial.eu.qualtrics.comPublic Perspectives on Digital Data Collection in Clinical TrialsThe most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today. 055
Rachel Phillips @rachpips.bsky.social · 05/09/2025They discuss how often "the apparent benefits of pharmacological interventions are less impressive, and more information emerges about harms they can cause" when using the CSR. You can read the full papers here: www.biomedcentral.com/collections/...biomedcentral.comThe collection, analysis and reporting of adverse events in randomised controlled trials 000
Rachel Phillips @rachpips.bsky.social · 05/09/2025In our latest adverse event webinar Jeffrey Aronson & Igho Onakpoya discuss their review that looked at how data from clinical study reports compare with data in published trial reports. Catch-up on their talk here: www.statsci.co.uk/webinar-seriesstatsci.co.ukWEBINARS | StatsCI 111
Reposted by Rachel PhillipsImperial Clinical Trials Unit @imperialctu.bsky.social · 03/09/2025And that's a wrap on this year's NIHR undergraduate internships. It's been a pleasure hosting three rising stars, they've each achieved so much in just 8 weeks. We can't wait to see what the future holds for them. Congratulations Alex, Mahima & Joe and good luck with the rest of your studies. 052
Reposted by Rachel PhillipsSuzie Cro @suziecro.bsky.social · 01/09/2025Are estimands being correctly used? A new review of protocols led by Timothy Clark shows many incorrectly defined estimand attributes. See the top areas for improvement & full results here: trialsjournal.biomedcentral.com/articles/10.... #Trials 3166
Rachel Phillips @rachpips.bsky.social · 29/08/2025And catch up with the full series of webinars here: www.statsci.co.uk/webinar-seriesstatsci.co.ukWEBINARS | StatsCI 000
Rachel Phillips @rachpips.bsky.social · 29/08/2025You can also read the full publication here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comClinical Study Reports—a systematic review with thematic synthesis: Part 2. Studying benefits, harms, and the benefit to harm balance of pharmacological interventions - TrialsBackground We define clinical study reports (CSRs) as standardized full reports of the protocols, results, and other pertinent details of clinical studies that are typically submitted by pharmaceutica... 100
Rachel Phillips @rachpips.bsky.social · 29/08/2025Thurs 4th September is the next webinar in our adverse event special series. Jeffrey Aronson & Igho Onakpoya will present their review of Clinical Study Reports & discuss the insights they offer when trying to quantify intervention benefits & harms. Sign up here: lnkd.in/ebMSPhdslnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 121
Reposted by Rachel PhillipsImperial Clinical Trials Unit @imperialctu.bsky.social · 29/08/2025Join us for Professor Victoria Cornelius' inaugural lecture - Under pressure: smarter trials for better health outcomes Thursday, 30 October 2025 17.30 - 18.30 GMT Register here: www.imperial.ac.uk/events/19688...imperial.ac.ukUnder pressure: smarter trials for better health outcomesJoin us for Professor Victoria Cornelius' inaugural lecture in person or online. 172
Rachel Phillips @rachpips.bsky.social · 29/08/2025And catch up with the full series of webinars here: www.statsci.co.uk/webinar-seriesstatsci.co.ukWEBINARS | StatsCI 000
Rachel Phillips @rachpips.bsky.social · 29/08/2025You can also read the full publication here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comClinical Study Reports—a systematic review with thematic synthesis: Part 2. Studying benefits, harms, and the benefit to harm balance of pharmacological interventions - TrialsBackground We define clinical study reports (CSRs) as standardized full reports of the protocols, results, and other pertinent details of clinical studies that are typically submitted by pharmaceutica... 100
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 26/08/2025Attending the International Society for Clinical Biostatistics this week? Don’t miss @ellievanvogt.bsky.social and Xiao Xuan who will be presenting these exciting topics: 041
Rachel Phillips @rachpips.bsky.social · 20/08/2025Don't miss this exciting opportunity to join us at @imperialctu.bsky.social @statsci.bsky.social. Closing 28th August 2025 000
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 19/08/2025Meet Alex Dixon, who is spending his summer experiencing life within ICTUs statistics and trial methodology group and conducting a research project with us as part of an NIHR undergraduate internship Find out what he has been up to here: www.statsci.co.uk/news 032
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 15/08/2025🔊We're hiring! Imperial Clinical Trials Unit are looking for an ambitious senior statistician with experience in clinical trials & design & analysis of adaptive trials to lead a research programme in antimicrobial resistance & data-enabled trials. Full details: www.imperial.ac.uk/jobs/search-...imperial.ac.ukDescriptionPlease note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment... 027
Rachel Phillips @rachpips.bsky.social · 30/07/2025🔊We're hiring! We are looking for an ambitious senior statistician with experience in clinical trials and the design and analysis of adaptive trials to lead a research programme in antimicrobial resistance and support colleagues in data-enabled trials. Full details: lnkd.in/eWpwsH6slnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 021
Rachel Phillips @rachpips.bsky.social · 03/07/2025And access the full article here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comAdverse event assessment in a parenting programme: experiences from a multisite randomised controlled trial - TrialsBackground Clinicians and researchers should consider the expected benefits and potential harms of an intervention. Parenting programmes are a widely used evidence-based intervention for child behavio... 000
Rachel Phillips @rachpips.bsky.social · 03/07/2025Inga Frantz & Nina Heinrichs discuss development of a comprehensive adverse event assessment tool based on their experiences in the RISE project, a multisite RCT that evaluated a parenting intervention for parents of children with increased levels of behaviour problems. 100
Rachel Phillips @rachpips.bsky.social · 03/07/2025Catch-up on today's adverse event webinar here: www.statsci.co.uk/webinar-seriesstatsci.co.ukWEBINARS | StatsCI 112
Rachel Phillips @rachpips.bsky.social · 25/06/2025Register for this talk and others in the series here: lnkd.in/eaW3MQrB You can also access the original paper here: doi.org/10.1186/s130...doi.orgAdverse event assessment in a parenting programme: experiences from a multisite randomised controlled trial - TrialsBackground Clinicians and researchers should consider the expected benefits and potential harms of an intervention. Parenting programmes are a widely used evidence-based intervention for child behavio... 000
Rachel Phillips @rachpips.bsky.social · 25/06/2025Next week we continue our adverse event special series. On Thursday 3rd July 1pm (BST), we host Inga Frantz who will be discussing their paper demonstrating the development and testing of a tool to assess the systematic collection of AEs in parenting intervention studies.lnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 101
Reposted by Rachel PhillipsStatsCI @statsci.bsky.social · 09/06/2025Attending #PSI2025 at Wembley stadium ⚽ this week? Don’t miss new research on a novel multiple imputation procedure for handling missing data in clinical trials targeting a treatment policy estimand by @suziecro.bsky.social James Roger & James Carpenter 043
Rachel Phillips @rachpips.bsky.social · 09/06/2025Suggesting that core harm outcomes along with serious, related and unexpected adverse events (SAEs, SARs, SUSARs), any pre-specified events, and events that lead to discontinuation of the treatment should always be reported. Seems there is still lots of room for improvement. 010
Rachel Phillips @rachpips.bsky.social · 09/06/2025This highlights there's still a need for an agreed consensus on what should be reported in journal articles. @vcornelius.bsky.social called for this in their 2022 JCE article doi.org/10.1016/j.jc...doi.orgRedirecting 110
Rachel Phillips @rachpips.bsky.social · 09/06/2025Eeek this makes for a grim read..... - Serious AEs (SAEs) and other AEs (OAEs) results omitted in 14% and 9% of articles, respectively - All-cause mortality missing in over 1/3 of articles - And when AE data was complete, discrepancies in 38% of SAEs, 86% of OAEs, and 36% of mortality outcomesjclinepi.comWhere are the harms? Underreporting of adverse events in clinical trials investigating targeted therapy for endocrine and metabolic disorders: an observational studyThis study aimed to assess the completeness and consistency of adverse event (AE) reporting in Clinicaltrials.gov and corresponding peer-reviewed publications for clinical trials investigating targete... 122
Reposted by Rachel PhillipsRichard Hooper @richardhooper.bsky.social · 06/06/2025📢UK undergraduates thinking about careers in medical statistics, clinical trial management, or other areas of applied health research: here's a great opportunity to join a multidisciplinary team on a paid internship (London-based) this summer. Pass it on! qmul-jobs.tal.net/vx/mobile-0/... 011
Rachel Phillips @rachpips.bsky.social · 05/06/2025Read the full article here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comDeveloping a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide - TrialsBackground The field of digital mental health has followed an exponential growth trajectory in recent years. While the evidence base has increased significantly, its adoption within health and care se... 000
Rachel Phillips @rachpips.bsky.social · 05/06/2025This work serves as a guide for academics and professionals, providing insights into the safety assessment required by regulatory bodies when a clinical investigation of a #DMHI is proposed, with methods, scales and tools that can be adapted for use in other similar researchtrialsjournal.biomedcentral.comDeveloping a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide - TrialsBackground The field of digital mental health has followed an exponential growth trajectory in recent years. While the evidence base has increased significantly, its adoption within health and care se... 100
Rachel Phillips @rachpips.bsky.social · 05/06/2025Catch up on today's #AdverseEvent special series webinar: www.statsci.co.uk/webinar-series We heard from Rayan Taher & Jenny Yiend about their work on developing a process for assessing the safety of a digital mental health intervention (DHMI) & gaining regulatory approval via the STOP case study.statsci.co.ukWEBINARS | StatsCI 120
Rachel Phillips @rachpips.bsky.social · 28/05/2025You can also find the full publication here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comDeveloping a process for assessing the safety of a digital mental health intervention and gaining regulatory approval: a case study and academic’s guide - TrialsBackground The field of digital mental health has followed an exponential growth trajectory in recent years. While the evidence base has increased significantly, its adoption within health and care se... 000
Rachel Phillips @rachpips.bsky.social · 28/05/2025Next Thursday, June 5th at 1pm (BST) we host our 4th webinar in our adverse event special series. Rayan Taher & Jenny Yiend will present their work on developing a process for assessing the safety of a digital mental health intervention & gaining regulatory approval. Register here: lnkd.in/eaW3MQrBforms.microsoft.comMicrosoft Forms 253
Rachel Phillips @rachpips.bsky.social · 23/05/2025- Andrew Bruce sharing his perspective of collecting and reporting adverse events in vaccine trials in the Gambia. With many more to come over the course of 2025! 000
Rachel Phillips @rachpips.bsky.social · 23/05/2025You can here from: - Regina Stegherr discussing the SAVVY project which aims to improve the analyses of adverse events in clinical trials using survival methods to handle varying follow-up & competing events. 100
Rachel Phillips @rachpips.bsky.social · 23/05/2025Catch up on all the talks from our Adverse Event special series so far: www.statsci.co.uk/webinar-seriesstatsci.co.ukWEBINARS | StatsCI 123
Reposted by Rachel PhillipsMarion Campbell @marionkcampbell.bsky.social · 19/05/2025In clinical trials it is not only potential benefits that should be measured - it is crucially important that any potential #harms are also investigated 1/7 #MethodologyMonday #118 175
Rachel Phillips @rachpips.bsky.social · 15/05/2025Read the original paper here: trialsjournal.biomedcentral.com/articles/10....trialsjournal.biomedcentral.comSurvival analysis for AdVerse events with VarYing follow-up times (SAVVY): summary of findings and assessment of existing guidelines - TrialsBackground The SAVVY project aims to improve the analyses of adverse events (AEs) in clinical trials through the use of survival techniques appropriately dealing with varying follow-up times and compe... 011
Rachel Phillips @rachpips.bsky.social · 15/05/2025Next week (May 22nd) we host our third webinar in our adverse event special series. Regina Stegherr will be discussing the SAVVY project which aims to improve the analyses of AEs in clinical trials using survival methods to handle varying follow-up & competing events. Register here: lnkd.in/eaW3MQrBlnkd.inLinkedInThis link will take you to a page that’s not on LinkedIn 111
Rachel Phillips @rachpips.bsky.social · 13/05/2025Collectively the articles indicate the scope of research needed for robust evaluation and inference, and how the whole pathway from collection to final inference needs careful attention. 000
Rachel Phillips @rachpips.bsky.social · 13/05/2025The articles covered early to late phase trials, simple to complex interventions, different trial contexts, research inclusion & public opinion. They provide examples & recommendations to support practical implementation. Check out the full list of articles here www.biomedcentral.com/collections/...biomedcentral.comThe collection, analysis and reporting of adverse events in randomised controlled trials 100
Rachel Phillips @rachpips.bsky.social · 13/05/2025In 2023 Trials invited submissions that related to the collection, analysis & reporting of adverse events in clinical trials. In this editorial @vcornelius.bsky.social & I summarise the submissions & discuss the implications on applied clinical trials & future methodological research rdcu.be/elLFardcu.beTrials special series - the collection, analysis and reporting of adverse events in randomised controlled trials 154
Reposted by Rachel PhillipsAnnie Wright @anniestats.bsky.social · 09/05/2025Honoured to have been awarded Best Presenter (2nd) at the @imperialcollegeldn.bsky.social School of Public Health PhD Symposium. It was great to share the results of my systematic review and show how they motivate my other work packages. Great confidence boost to present at the SCT Conference! 032
