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Zack Williams, MD, PhD

@quantpsychiatry.bsky.social
3.2K followers 5.2K following 654 posts

•Autistic (+ADHD, OCD, Tourettes) autism researcher and trainee psychiatrist (rising PGY-1) •YaleCSC➡️VanderbiltMSTP➡️UCLA •Catatonia enthusiast, patient advocate, stats guy •MH research/methods/advocacy, autism/neurodiversity, academic medicine, dumb jokes

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Reposted by Zack Williams, MD, PhD
Hari Srinivasan @neuroscientist.bsky.social · 05/05/2025
"Doctor-Doctor" Zack Williams shares insights into his research and his view of the world, in this spotlight interview with me. Check out the link below. Wishing you lots of luck Zack in the next chapter of your life. www.vanderbilt.edu/autismandinn... @quantpsychiatry.bsky.social
vanderbilt.edu
FCAI Spotlight: The Many Layers of Zack Williams by Hari Srinivasan
This article is part of a series highlighting the work and people associated with the Frist Center for Autism and Innovation (FCAI) at Vanderbilt University. The Frist Center brings together engineers...
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Reposted by Zack Williams, MD, PhD
Hannah Morton @hannahmorton.bsky.social · 25/04/2025
Excited for another year of the Autism PROMnet Special Interest Group at #INSAR2025! Come chat with us about using valid, accessible, and inclusive measures for and by autistic people in autism research 🙌 Friday, May 2 at 10:30AM (#706) www.autismpromnet.org @quantpsychiatry.bsky.social
Improving patient reported outcome measures (proms) in autism research. Bridging the gap between advanced psychometric techniques and stakeholder priorities. Friday May 2 10:30 AM - 12:00 PM Room 4C-1,2 (4th floor). SIG Leaders Hillary K. Schiltz Zachary J. Williams. INSAR annual meeting.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 20/03/2025
Excited to share my latest paper in @autisminadulthood.bsky.social (led by the fantastic @drjessicaphd.bsky.social). We pooled data from the Columbia Suicidality Severity Rating Scale from autistic youth and adults in 3 countries (US, Canada, Australia) to assess trajectories across the lifespan...
liebertpub.com
Elevated Suicidal Thoughts and Behaviors and Nonsuicidal Self-Injury in Autistic Youth and Adults: A Multinational Study | Autism in Adulthood
Background: Autistic people are at significant risk for suicidal thoughts and behaviors (STBs) and nonsuicidal self-injury (NSSI). We examined STB and NSSI in different age-groups, considering sex- an...
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 12/02/2025
Really enjoyed being interviewed for this feature on misophonia and misophonia research in @asteriskmag.bsky.social! asteriskmag.com/issues/09/th...
asteriskmag.com
The Unbearable Loudness of Chewing—Asterisk
Why do some people find certain sounds intolerable? And why has it taken so long for scientists to get even a preliminary answer?
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Reposted by Zack Williams, MD, PhD
Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 01/02/2025
To all of the #INSAR members voting in the upcoming board election, (not that anyone cares but) I'm officially endorsing my good (bluesky-less) friend and colleague Mirko Uljarević for INSAR treasurer! With quant skills like his, the society's money is in good hands.
A very handsome and competent physician-scientist who is totally able to handle the finances of the major autism research professional society.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 01/02/2025
To all of the #INSAR members voting in the upcoming board election, (not that anyone cares but) I'm officially endorsing my good (bluesky-less) friend and colleague Mirko Uljarević for INSAR treasurer! With quant skills like his, the society's money is in good hands.
A very handsome and competent physician-scientist who is totally able to handle the finances of the major autism research professional society.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 30/01/2025
Really exciting news - new med soon to be on the market for acute pain, mechanism of peripheral Nav1. 8 channel inhibition (not habit forming). Super exciting to see what this med and others like it can do to transform health care! news.vrtx.com/news-release...
news.vrtx.com
Vertex Announces FDA Approval of JOURNAVX™ (suzetrigine), a First-in-Class Treatment for Adults With Moderate-to-Severe Acute Pain | Vertex Pharmaceuticals Newsroom
-- JOURNAVX is the first and only approved non-opioid oral pain signal inhibitor and the first new class of pain medicine approved in more than 20 years -- -- JOURNAVX is an effective and well-tolerat...
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Reposted by Zack Williams, MD, PhD
Awais Aftab @awaisaftab.bsky.social · 19/01/2025
The Unbearable Incoherence of Heritability: Interview with Eric Turkheimer ( @ent3c.bsky.social ) “The empirical end to the Galtonian project is more whimper than bang.” www.psychiatrymargins.com/p/the-unbear...
psychiatrymargins.com
The Unbearable Incoherence of Heritability: Interview with Eric Turkheimer
Eric Turkheimer is Hugh Scott Hamilton Professor of Psychology at University of Virginia.
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Reposted by Zack Williams, MD, PhD
Adam Fare 🖤🤍💜 @adamfare1996.bsky.social · 16/01/2025
You’re allowed to say “I hate being disabled”. This isn’t internalised ableism, it’s your reality. Truth is, being disabled is… disabling. It’s overwhelming, debilitating, and yeah… for me (and I’m sure many others)… it’s shit.
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Reposted by Zack Williams, MD, PhD
Jorge A. Caballero, MD @datadrivenmd.social · 14/01/2025
✨ Bluesky search tips and tricks Add `from:me` to find your own posts Add `to:me` to find replies/posts that mention you Add `since:YYYY-MM-DD` and/or `until:YYYY-MM-DD` to specify a date range Add `domain:theonion.com` to find posts linking to The Onion See more at bsky.social/about/blog/0...
bsky.social
Tips and Tricks for Bluesky Search - Bluesky
Let’s dive into all the tips and tricks for advanced Bluesky search!
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Reposted by Zack Williams, MD, PhD
JAMA @jama.com · 13/01/2025
Viewpoint discusses the US Supreme Court's decision in United States v Skrmetti, which will determine if Tennessee’s ban on gender-affirming care for minors violates the Equal Protection Clause. #MedSky ja.ma/4h7WUVv
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Reposted by Zack Williams, MD, PhD
Isabelle Rosso @irosso.bsky.social · 13/01/2025
EMA study of dissociative episodes shows that heart rate does not change in relation to dissociation intensity, counter to predictions of "hypoarousal models" of dissociation. "Dissociative episodes and concurrent heart rate in patients with PTSD..." www.sciencedirect.com/science/arti...
sciencedirect.com
Dissociative episodes and concurrent heart rate in patients with PTSD – An ecological momentary assessment
Dissociative symptoms are a frequent complication in posttraumatic stress disorders affecting about a third of all PTSD patients. While theoretical mo…
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 01/01/2025
As 2024 comes to a close, I'm wishing all the best to my Bluesky family. It's been a hard year for me personally, but I've been able to persevere and come out the other side with a PhD, almost an MD, my marriage intact (no thanks to the PhD), and a bright future. Here's to a better 2025 for all!
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Reposted by Zack Williams, MD, PhD
Dani Donovan 👩🏻‍🎨 ADHD Comics @danidonovan.com · 24/12/2024
just a reminder: it’s okay if you get overwhelmed today. there’s a lot going on: noise, people, emotions. demands for your attention/energy. so take a few minutes. find a quiet space to catch your breath. check your phone. do a quick reset. you’re doing great. hang in there.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 21/12/2024
An exciting day in autism epidemiology - numbers are out from the 2021 GBD study. Who's "disease" framing and associated language aside, this is a big effing deal for understanding the prevalence and impact of autism across the globe, especially in LMICs! Overall prevalence was 0.79% (0.66-0.93)
thelancet.com
The global epidemiology and health burden of the autism spectrum: findings from the Global Burden of Disease Study 2021
The high prevalence and high rank for non-fatal health burden of autism spectrum disorder in people younger than 20 years underscore the importance of early detection and support to autistic young people and their caregivers globally. Work to improve the precision and global representation of our findings is required, starting with better global coverage of epidemiological data so that geographical variations can be better ascertained. The work presented here can guide future research efforts, and importantly, decisions concerning allocation of health services that better address the needs of all autistic individuals.
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Reposted by Zack Williams, MD, PhD
Chris Aiken, MD @chrisaikenmd.bsky.social · 20/12/2024
Naltrexone treats #alcohol use. Avoiding it in patients with liver problems out of safety concerns is neither helpful nor evidence based, argues new paper: pubmed.ncbi.nlm.nih.gov/39655573 Even in cirrhosis pubmed.ncbi.nlm.nih.gov/39640196 #sober #sobriety #addiction #alcoholism #psychiatry
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 20/12/2024
A very solid critique of TBKTS. Also highly recommend reading the 2019 critique by Scott Alexander (slatestarcodex.com/2019/11/12/b...), which is a bit more academic but nevertheless spot-on IMO. There's far too much anecdata driving the the book's recs, and it draws many unscientific conclusions.
slatestarcodex.com
Book Review: The Body Keeps The Score
I. The Body Keeps The Score is a book about post-traumatic stress disorder. The author, Bessel van der Kolk, helped discover the condition and lobby for its inclusion in the DSM, and the brief fora…
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 19/12/2024
Brexpiprazole [Rexulti] (2-3 mg flex dosing) + sertraline (150 mg fixed) beat sertraline + placebo for PTSD symptoms in a large-scale trial published in JAMA Psychiatry (n=416; LS mean CAPS difference at 10 wks −5.59, 95% CI [−8.79, −2.38] P < .001). Dropouts high (35%+), but *more* in PBO group.
jamanetwork.com
Brexpiprazole and Sertraline for Posttraumatic Stress Disorder
This parallel-design, double-blind, randomized clinical trial investigates if combination treatment with brexpiprazole and sertraline is efficacious, safe, and well tolerated in patients with posttrau...
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Reposted by Zack Williams, MD, PhD
Annie Hickox @dranniehickox.bsky.social · 17/12/2024
Thanks to @jonathanstea for sharing my story as both a mother and clinical psychologist grappling with my daughter’s breakdown when she was at university. I know it will help so many others who find themselves facing social media stigma when our family members are struggling.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 17/12/2024
At a Christmas party I just attended, one of my (extremely online young professional) friends kept quoting Chicago, saying "It was a murder, but not a crime." Too many lefty millennials are really finding this *heinous crime* unproblematic (IRL too, not just in the context of memes). Sigh...
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Reposted by Zack Williams, MD, PhD
Randall Munroe @xkcd.com · 16/12/2024
Phase Transition xkcd.com/3025
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 16/12/2024
CARES is now through both houses of congress and headed to Biden's desk to be signed into law! Exciting to see that autism research will continue to be funded, but this wasn't without a *significant* lift on all the advocacy orgs' parts. thearc.org/blog/autism-...
thearc.org
The Autism CARES Act Has Passed!
This victory represents a critical step forward in addressing the needs of people with disabilities. Here's what this legislation means.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 10/12/2024
@drmbothapsych.bsky.social is here - v important!
bsky.app
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Jessica Schleider, PhD @jschleiderphd.bsky.social · 09/12/2024
📢 Our lab's latest, out today in JAMA Pediatrics: "State Parental Consent Law and Treatment Use Among Adolescents With Depression" jamanetwork.com/journals/jam... TL;DR Teens with depression living in states that require parent consent for mental health treatment may be less likely to access care 🧵
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 09/12/2024
So glad to see you here!
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 09/12/2024
Fancy name tag for fancy government work!
Zachary Williams printed on a national academies of science engineering and medicine name tag.
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Reposted by Zack Williams, MD, PhD
Mark Cuban @mcuban.bsky.social · 06/12/2024
This is going to save hospitals a lot of money ! www.pennmedicine.org/news/news-re...
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 06/12/2024
Oof - satire that gets me.
babylonbee.com
Every Single Human Behavior Now Classified As Autism Or ADHD
U.S. — Secretary of Health and Human Services Xavier Becerra announced in a press conference Thursday that, going forward, every single human behavior would now be classified as either Autism Spectrum...
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Reposted by Zack Williams, MD, PhD
Black In Neuro @blackinneuro.bsky.social · 04/12/2024
We are now up to 78 accounts on our Black In Neuro starter pack! Be sure to check back and make sure you have everyone added 🤗 Please let us know if we missed you! #BlackInSTEM #Neuroskyence #Psychology #AcademicSky 🧪 go.bsky.app/F8PpdPe
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Keezy Young🌼 @keezyyoung.bsky.social · 04/12/2024
alito comparing being trans to schizophrenia is a slap in the face to both trans people AND people with severe mental illness. not because of the comparison (in either direction), but because they're fundamentally completely different things outside of BOTH DESERVING ACCESS TO PROPER MEDICAL CARE
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Katie Mack @astrokatie.com · 04/12/2024
I honestly believe all LLM results should come with a disclaimer reminding people that the thing doesn’t (and absolutely cannot) know any facts or do any reasoning; it is simply designed to *sound* like it knows facts and frequently sweeps some up accidentally in the process.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 04/12/2024
!!!
nytimes.com
Brian Thompson, UnitedHealthcare CEO, Is Fatally Shot in Midtown Manhattan: Live Updates
The executive, Brian Thompson, was shot in the chest in what people briefed on the investigations said appeared to be a targeted attack.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 02/12/2024
Help, it's too early for this much cringe!
SpongeBob holding a restraining order that declares that this shit is not to be allowed within 15 feet of my fuckin eyes.
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Kemi Babagbemi MD, FACR🐳 @kemimdrad.bsky.social · 01/12/2024
#RSNA24 attendees join us in #hcwvshunger Consider donating to @partnersinhealth.bsky.social www.pih.org/injusticehas... and log for team #DiagnoseAndTreats hcwvshunger.org/how-to-donate/
pih.org
Injustice has a cure
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 01/12/2024
I missed it when he joined but @chrisaikenmd.bsky.social (of Carlat Report fame) finally took the plunge and came over here to the good place! Excited to now bother him on a different platform! If, like me, you're missing your "daily dose of practice-changing research," give him a follow.
bsky.app
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Jillian Bybee, MD @lifeandpicu.bsky.social · 30/11/2024
Let’s make our donations go even farther! 📣Attention TRAINEES: I’ll be matching donations all weekend up to $300. Tell me where you donated and how much, and I’ll match your donation to the same place AND put it toward whatever team you want (not just #Kidvengers). Spread the word! #HCWvsHunger
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Aaron Fisher @aaronjfisher.bsky.social · 30/11/2024
For sure
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 30/11/2024
I absolutely LOVE the anti-planner, a "choose-your-own-adventure" guide of comedy-filled beautifully-animated executive-functioning hacks by and for ADHDers. On sale for $43 this weekend! From @danidonovan.com (ADHD comics), who hasn't paid me a cent (but I'm sure my patients think she has)!
anti-planner.com
The Anti-Planner: How to Get Sh*t Done When You Don’t Feel Like It
🇺🇸 🇨🇦 🇦🇺 Available in USA, Canada & Australia. (European restock coming soon—click HERE to get notified!) Do you know what you need to do, but struggle to get yourself to do it? Get bored easily? Aban...
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 29/11/2024
Want to keep track of the number of bluesky users at any given moment? Look no further than bcounter.nat.vg (23.39 million at the time of posting!)
bcounter.nat.vg
Bcounter
Almost-real-time Bluesky user count
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Reposted by Zack Williams, MD, PhD
Maarten van Smeden @maartenvsmeden.bsky.social · 29/11/2024
Data are not biased. Datasets can be small, selective, incomplete, full of error, and is mostly a combination of these. Depending on what you do with such a dataset, some estimators (but not always all of them) may be biased and results unreliable and untrustworthy
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 29/11/2024
Third year of our new Thanksgiving tradition - beef wellingtons! Who needs turkey anyways? Seven hours of cooking, but well worth it!
One masterfully cooked beef wellington on a plate with some crispy Brussels sprouts. In the background, a tray of waaaaay too many wellingtons for me and my wife to eat. Come by and have one!
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 28/11/2024
Watching the national dog show with the family, and clearly my boys want to heckle the competition and day how much cuter they are than the toy breed contestants (subtitles on because we can't hear shit otherwise).
Cody the cavalier jumps up on the TV stand and borks at a Pekingese on TV, being a total fucking nuisance, but also adorable... Charlie and Cody, two cavaliers, bork like total menaces at other dogs doing agility courses while they've never worked a day in their lives.
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Shematologist, MD @shematologist.medsky.social · 28/11/2024
Good morning! Thankful for all of you turkeys out there but especially those that want to help us feed others. #HCWvsHunger 2024 starts tonight at 6pm EST. You can help in many ways 🍎 post/repost 🍎 donate to any org fighting hunger & log donation at HCWvsHunger.org 🍎 invite everyone you know
hcwvshunger.org
Healthcare Workers vs Hunger
Healthcare workers vs Hunger is an annual friendly competition between teams of healthcare workers to help relieve food insecurity.
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William B. Fuckley @opinionhaver.bsky.social · 28/11/2024
academic generational trauma (coding things the same weird fucking way that your advisor does, and their advisor before them) because it's become a habit
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Mubashar “Mubs” Iqbal @mubashariqbal.com · 27/11/2024
I love that people think about @blueskydirectory.com when they want to find starter packs, but it's already so much more than that. Excited to add even more to it: blueskydirectory.com If you have any suggestions, please let me know...
blueskydirectory.com
The Ultimate Directory of tools and applications for Bluesky
A curated collection of all things relating to the Blue Sky social media platform.
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 27/11/2024
Another phenomenal person has joined bluesky! Follow @gertjanvanaken.bsky.social if you want rigorous (philosophically and clinically informed) updates on what it means for a treatment to be "neurodiversity-affirming!" Also, if you haven't, read his paper: www.frontiersin.org/journals/psy...
frontiersin.org
Frontiers | Addressing the autism mental health crisis: the potential of phenomenology in neurodiversity-affirming clinical practices
The neurodiversity movement has introduced a new era for autism research. Yet, the neurodiversity paradigm and the autism clinic remain largely unconnected. ...
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 26/11/2024
Huge if this actually goes through (and bigger if private insurers follow suit). May just make the Trump/Oz CMS get some egg-on-face by squashing a popular policy immediately after rolling into office, but wouldn't covered on-label GLPs be nice! www.statnews.com/2024/11/26/w...
statnews.com
Medicare moves to expand coverage for weight-loss drugs Wegovy, Zepbound
The Biden administration is proposing a major expansion of how Medicare and Medicaid cover the weight-loss drugs Wegovy and Zepbound.
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Dorothy Bishop @deevybee.bsky.social · 26/11/2024
Andrew Gelman's take on research lines that just won't die statmodeling.stat.columbia.edu/2024/11/26/i...
statmodeling.stat.columbia.edu
“I wonder just what it takes to get people to conclude that a research seam has been mined to the point of exhaustion.” | Statistical Modeling, Causal Inference, and Social Science
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Zack Williams, MD, PhD @quantpsychiatry.bsky.social · 26/11/2024
PSA: One of my favorite people (Heather Brown aka @thriving-w-autism.bsky.social has finally joined this lovely platform)! Give her a follow if you're interested in autism/disability (self-)advocacy, higher education, mental health/well-being, participatory research, or that Canadian politeness!
Very kawaii mindflayer with hearts blushing. Caption says "Exquisite"
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