Abstract. Lung squamous cell carcinoma (LUSC) is a basal-like subtype of lung cancer with limited treatment options. While prior studies have identified tumor-propagating cell states in squamous tumor...

Lung squamous cell carcinoma (LUSC) is basal-like subtype of lung cancer with limited treatment options. While prior studies have identified tumor-propagating cell states in squamous tumors, the broader landscape of intra-tumoral heterogeneity within LUSC remains poorly understood. Here, we employ S …

Outstanding Research Opportunity in Cancer-Focused Bioinformatics and Computational Biology at the Lewis Katz School of Medicine at Temple Universi...

Nature - Basal cells, rather than neuroendocrine cells, have been identified as the probable origin of small cell lung cancer and other neuroendocrine–tuft cancers, explaining...

ALT: a woman is rubbing her nose with her fist while another woman looks on .

By transcriptomic analysis, Lubrano et al. demonstrate that FAK-regulated pathways are enriched in BRAFi+MEKi-resistant melanoma lesions. In BRAF V600E melanomas, MAPK inhibition decreases RhoE (RND3) expression, activating the RhoA-FAK-AKT pathway and…

El estado previo de las células madre influye de forma “decisiva” BARCELONA, 25 (EUROPA PRESS) Un estudio del Instituto de Investigación Biomédica (IRB) de Barcelona ha r...

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March 7, 2025. Washington DC and Nationwide. Because Science is for everyone.

Directly contact your elected officials about the importance of cancer research, the need for continued funding and the latest lifesaving breakthroughs. In the United States, you can do so by sending ...

Directly contact your elected officials about the importance of cancer research, the need for continued funding and the latest lifesaving breakthroughs. In the United States, you can do so by sending ...

Postdoctoral fellow within the Aging + Cardiovascular Discovery Center at Temple University

Move to cut indirect cost rate to 15% could cost universities billions of dollars

The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.

NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

Splinter is your home for news and opinions that challenge power in our political and economic system that's becoming more unhinged each and every day.

The administration has forced crucial scientific activity to grind to a halt. It’s an act of national suicide.