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Dan Polyak

@polym0n.bsky.social

Senior Scientist @Merck | PhD @Brandeis | synthetic chemist | currently loving gardening, exploring nature, looking at birds, crocheting, and petting my cats

Posts Replies Media

Dan Polyak @polym0n.bsky.social · 15/02/2026

Awesome shot!

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Dan Polyak @polym0n.bsky.social · 30/12/2025

The Severance Package

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Reposted by Dan Polyak

Kevin A. Scott, PhD @sculpturatus.bsky.social · 30/12/2025

Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.

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Dan Polyak @polym0n.bsky.social · 04/05/2025

Got a plot at my local community garden and it has been such a pleasant experience. Trying out Square Foot Gardening, not sure how the harvest is going to turn out but at least it looks pretty

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Dan Polyak @polym0n.bsky.social · 05/04/2025

Life imitates art

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Reposted by Dan Polyak

Mark Levin @levinchem.bsky.social · 03/04/2025

If you're interested in a break from the doom-and-gloom, may I recommend our article, online today @nature.com A solution to the pyrazole alkylation problem, leveraging S-to-NR atom replacement. Skeletal editing has strategic value, outside of late-stage! www.nature.com/articles/s41...

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