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Pobezinsky Lab

@pobezinskylab.bsky.social

33 followers 78 following 1 posts

T cell responses, formation of immunological memory. Tumor immunology and infection.

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Reposted by Pobezinsky Lab

Pobezinsky Lab @pobezinskylab.bsky.social · 22/08/2025

A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors | Science Advances www.science.org/doi/10.1126/... Our new story just came out in Science Advances! So proud of Adam Lynch and the rest of our team.

A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors

Thymic-derived naïve Dapl1+ CD8 T cells contain a subset preprogrammed to form memory-like cells upon activation.

Reposted by Pobezinsky Lab

Benjamin Furtwängler @bfurtwa.bsky.social · 22/08/2025

We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social. www.science.org/doi/10.1126/... 🧵

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics

Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

Pobezinsky Lab @pobezinskylab.bsky.social · 22/08/2025

A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors | Science Advances www.science.org/doi/10.1126/... Our new story just came out in Science Advances! So proud of Adam Lynch and the rest of our team.

A Dapl1+ subpopulation of naïve CD8 T cells is enriched for memory-lineage precursors

Thymic-derived naïve Dapl1+ CD8 T cells contain a subset preprogrammed to form memory-like cells upon activation.