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Pierre Simon Garcia

@pierresimongarcia.bsky.social
121 followers 227 following 8 posts

Researcher in CNRS (France, Marseille)🇫🇷🏳️‍🌈 Bioinfo 💻 Phylogeny 🌳 Genomics 🧬 Bacteria and Archaea 🦠 Metabolism ⌬

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Reposted by Pierre Simon Garcia
Simonetta Gribaldo @sgribaldo.bsky.social · 23/09/2026
Interested in #archaea, #methane, #cell-envelopes? New paper out @nature.com ! We discovered an enzyme that specifically cleaves the cell wall of methanogens, revealing a new chemical structure of archaeal peptidoglycan, 50 yrs after its first description www.nature.com/articles/s41... #MicroSky 🧵👇
nature.com
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Reposted by Pierre Simon Garcia
Nature @nature.com · 23/02/2026
Nature research paper: Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor go.nature.com/4rSfRRw
go.nature.com
Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature
Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgardarchaeota, in conditions that may have given rise to early eukaryotes.
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Reposted by Pierre Simon Garcia
Evgenii Protasov @evgenii-protasov.bsky.social · 08/02/2026
Reassessing viral origins and evolutionary placement in the tree of life #OriginofLife #TreeofLife #Evolution #virus #phage #MicroSky doi.org/10.1007/s104...
doi.org
Reassessing viral origins and evolutionary placement in the tree of life - Antonie van Leeuwenhoek
The quest to fit all cellular beings in one picture frame as the universal Tree of Life (ToL) has always been a daunting task for evolutionary biologists. Over the decades, ToL has emerged from a dich...
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Reposted by Pierre Simon Garcia
Tobias Warnecke @tobiaswarnecke.bsky.social · 14/08/2025
Archaea are often surrounded by bacteria. But is there ever active conflict between the two? Can archaea kill bacteria? If so, how do they do it? Work by @romainstrock.bsky.social shows that some archaea can kill bacteria by secreting peptidoglycan hydrolases. journals.plos.org/plosbiology/...
journals.plos.org
Archaea produce peptidoglycan hydrolases that kill bacteria
Archaea regularly interact with bacteria but reports of archaea killing bacteria are very rare. This study shows that many archaea encode peptidoglycan hydrolases, which specifically target bacterial ...
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Reposted by Pierre Simon Garcia
Lars Eicholt @lacholt.bsky.social · 28/01/2026
Check out our new review in Nature Reviews Genetics on de novo emerged genes and proteins. How they emerge, are lost and persist - and how de novo emerged proteins relate to randomized proteins! @bornberglab.bsky.social www.nature.com/articles/s41...
nature.com
Emergence and evolution of protein-coding de novo genes - Nature Reviews Genetics
De novo gene evolution entails the birth of new genes from previously non-coding DNA. In this Review, Bornberg-Bauer and Eicholt overview how protein-coding de novo genes are identified, the mechanist...
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Reposted by Pierre Simon Garcia
CNRS Biologie @cnrsbiologie.bsky.social · 03/02/2026
#ResultatScientifique🔎| Dans un article publié dans @natecoevo.nature.com des scientifiques proposent une relecture de l’origine et de l’évolution des oxydoréductases. ✍️ @pierresimongarcia.bsky.social et Guillaume Borrel 👋 @cnrs-dr12.bsky.social @univ-amu.fr @pasteur.fr ▶️ buff.ly/fjqI60P
buff.ly
La fascinante histoire évolutive des oxydoréductases, nanomachines clés de la bioénergétique
Dans un article publié dans Nature Ecology & Evolution, des scientifiques proposent une relecture de l’origine et
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Pierre Simon Garcia @pierresimongarcia.bsky.social · 03/02/2026
Passioned by #bioenergetics? Do not miss our new article on the evolutionary history of oxidoreductases with G. Borrel and @sgribaldo.bsky.social @archaeal.bsky.social @valdeanda.bsky.social @pasteur.fr @cnrs.fr @cnrsbiologie.bsky.social @natecoevo.nature.com (www.nature.com/articles/s41...).
nature.com
Evolution and diversity of oxidoreductases involved in redox balance and energy conservation - Nature Ecology & Evolution
HORBEC are protein complexes involved in the regulation of redox balance and energy conservation. The authors develop a bioinformatic tool for HORBEC annotation in bacterial and archaeal genomes and r...
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