iiinova — where your digital self keeps evolving

Peter MacPherson @petermacp.bsky.social · 19/09/2026

Very pleased to contribute to this meta-analysis. Among contacts of #TB, protection from preventive therapy waned quickly in high incidence settings, but persisted for years in low and medium incidence settings authors.elsevier.com/sd/article/S... @uofgshw.bsky.social 🦠🧪🛟

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Peter MacPherson @petermacp.bsky.social · 11/08/2026

Walking some of the West Highland Way over the last few days and found this in Dryman Spar. Don’t everyone rush at once.

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Peter MacPherson @petermacp.bsky.social · 06/08/2026

#Multimorbidity with #tuberculosis is under-recognised. We followed nearly 2000 adults with #TB in 🇿🇦 for 18m. Multimorbidity was very common, and associated with large ⬆️ in risk of death. #idsky #TBsky 🧪🛟 doi.org/10.1371/jour... @uofgshw.bsky.social @tomwingfield.bsky.social

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Peter MacPherson @petermacp.bsky.social · 30/07/2026

🚨New publication🚨 Despite global scale-up of ART for #HIV, bloodstream infection with M. tuberculosis in hospitalised adults remains common In a 7 country study, PLHIV with #TB in blood were 2.7x more likely to die by 30days doi.org/10.1093/ofid... @uofgshw.bsky.social @biancasossen.bsky.social

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Peter MacPherson @petermacp.bsky.social · 09/06/2026

New: Risk & cause of death among people living with #HIV admitted to hospital Overall mortality remains unacceptably high (16%) & probably hasn’t changed since 2000 AIDS-related conditions (72%) esp. #TB (27%) main cause of death dx.doi.org/10.1002/jia2... @uofgshw.bsky.social #IDSky #TBSky 🧪🛟

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Peter MacPherson @petermacp.bsky.social · 24/05/2026

We updated our review of sex diff. in #TB prevalence In 102 surveys (4.7M participants) men were 2x as likely to have TB than women Evidence consistent with sex differences widening over time 🧪🛟 journals.plos.org/plosmedicine... @nswartwood.bsky.social @kchorton.bsky.social @uofgshw.bsky.social

A map showing countries where surveys were conducted. Bar chart shows the number of surveys per country

A forest plot showing the empirical and modelled estimates of sex differences in TB prevalence between men and women

Plots showing the empirical and time trends on male-to-female tuberculosis prevalence ratio overall, and by WHO region

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Peter MacPherson @petermacp.bsky.social · 06/05/2026

Yes! The otters are lovely, but I prefer the mackerel £5, and red squirrel £20 notes. Did you know that three different banks issue notes in Scotland, all with different sets of designs? en.wikipedia.org/wiki/Banknot...

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Peter MacPherson @petermacp.bsky.social · 03/05/2026

Great post! And agree that addresses are fantastic. For where there is no municipal address system, we built a tool based on high-resolution satellite maps and community-tagged locations. Works brilliantly for navigation (combine with 3W), and for epidemiology. www.cambridge.org/core/journal...

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Peter MacPherson @petermacp.bsky.social · 08/04/2026

We are staying on the Kintyre Peninsula, and took the ferry across to Gigha (community owned island in inner Hebrides) yesterday. Other favourites are Mull and North Uist. Always welcome if coming past Glasgow.

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Peter MacPherson @petermacp.bsky.social · 08/04/2026

Me and the family on a remote Scottish island today.

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Peter MacPherson @petermacp.bsky.social · 08/04/2026

We found that #TB epidemics are becoming increasingly urbanised. Important implications for supporting effective public health interventions to end tuberculosis epidemics. 🧪 #MedSky @uofgshw.bsky.social @kchorton.bsky.social @nswartwood.bsky.social journals.plos.org/plosmedicine...

Graph of model predicted urban-to-rural TB prevalence between 2000 and 2024

Graph showing predicted percentage of TB cases that were urban and rural between 2000 and 2024

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Peter MacPherson @petermacp.bsky.social · 30/03/2026

New study led by @alexandra-richards.bsky.social. Reducing men’s TB risk and improving treatment access could have big impacts on #TB incidence and deaths for men, women, and children. www.nature.com/articles/s43... @kchorton.bsky.social @uofgshw.bsky.social @lightontb.bsky.social

Bar charts showing impact of interventions on TB incidence for men, women, and children

Graphs showing impact of interventions on TB notifications in 4 countries

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Peter MacPherson @petermacp.bsky.social · 24/03/2026

This #WorldTBday is a honour to be in Blantyre, Malawi, where we kicked off recruitment into the @wellcometrust.bsky.social funded ZAMSA-TB study. The team are developing new epidemiological methods to measure future vaccine effectiveness in the community.

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Peter MacPherson @petermacp.bsky.social · 13/02/2026

Very please to share the results of the SaDAPT Trial. In Malawi and Lesotho, same-day initiation for ART for #HIV in people with #TB symptoms was non-inferior to ART initiation after TB investigations, and with no safety concerns. authors.elsevier.com/c/1mb~68MsVo... @uofgshw.bsky.social

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Peter MacPherson @petermacp.bsky.social · 23/01/2026

I have been messing around with biscale plots here… but not sure whether they work on not. Could work with a hex plot too I guess

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Peter MacPherson @petermacp.bsky.social · 28/10/2025

Was very fortunate to see Counting Crows play last night… only 27 years since I last saw them play in Scotland.

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Peter MacPherson @petermacp.bsky.social · 04/10/2025

New preprint (NOT PEER-REVIEWED) Community screening for #TB can reduce incidence. But we don’t know how best to target. Targeting based on neighbourhood ARTI from convenience samples can substantially improve health and cost-effectiveness vs untargeted screening. www.medrxiv.org/content/10.1...

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Peter MacPherson @petermacp.bsky.social · 29/09/2025

⚡️New publication⚡️ We investigated the risk and determinants of mortality in people notified with Invasive Group A Streptococcal disease in Scotland between Jan 2017 and Dec 2024. doi.org/10.1016/j.ij... @uofgshw.bsky.social

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Peter MacPherson @petermacp.bsky.social · 26/09/2025

⚡️New publication⚡️ WHO clinical staging is not sufficiently accurate to identify advanced #HIV. CD4 testing remains essential to reduce morbidity and mortality. doi.org/10.1111/hiv.... @uofgshw.bsky.social @joejarvis.bsky.social

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Peter MacPherson @petermacp.bsky.social · 22/09/2025

Are there more people with #TB in cities or rural areas? In a 🚨new🚨 preprint (NOT PEER REVIEWED) we modelled urban-rural TB trends from 2000-2023 in 26 countries with 4.6 billion people. www.medrxiv.org/content/10.1...

A plot, facetted by country, showing the percentage of TB that is urban and rural between 2000-2023

A forest plot, showing estimates of the urban to rural TB prevalence in 46 studies

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Peter MacPherson @petermacp.bsky.social · 22/08/2025

Reductions in development assistance for health funding threaten decades of progress in Africa 🦠🧪🛟 journals.plos.org/plosmedicine...

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Peter MacPherson @petermacp.bsky.social · 15/08/2025

About half of people with #TB are asymptomatic (aTB). Calls have been made to stratify treatment and estimate incidence based on aTB case definitions In this preprint we raise concerns that symptoms are an inadequate & inconsistent classifier of TB state, being highly influenced by context ⬇️link

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Peter MacPherson @petermacp.bsky.social · 08/07/2025

Really great plot. And as per other comments, would have fewer groups for the categorical. In the context of meta-analysis of aggregate data, we had a lot of fun figuring out how to include age as a predictor in this paper www.sciencedirect.com/science/arti...

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Peter MacPherson @petermacp.bsky.social · 01/07/2025

In meta analysis of data from nearly half a million people, we found that men have higher M. #tuberculosis immunoreactivity risk than women. Likely to be key driver of sex differences in global tuberculosis morbidity & mortality @hannahrickman.bsky.social 🛟🧪 authors.elsevier.com/sd/article/S...

The first page of the Lancet Public Health manuscripts

Two graphs showing a) prevalence of MTB immunoreactivity by sex and age and b) ARTI by sex and age

Figure showing male-to-female prevalence ratio in MTB immunoreactivity

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Peter MacPherson @petermacp.bsky.social · 22/05/2025

🎉New preprint led by Greta Wood🚨 Among ~2000 adults with #TB in 🇿🇦 #multimorbidity was extremely common (86%) and strongly predictive of death at 15 months Need for screening and management. 🧪🛟🦠 papers.ssrn.com/sol3/papers.... @tomwingfield.bsky.social @uofgshw.bsky.social @lstmnews.bsky.social

Title and abstract page of the manuscript

Bar graphs showing prevalence of TB multimorbidity, stratified by key variables

Graphs showing hazard of death among people with TB multimorbidity

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Peter MacPherson @petermacp.bsky.social · 05/05/2025

Today’s walk was around Loch Ard.

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Peter MacPherson @petermacp.bsky.social · 04/05/2025

Loch Lomond looking spectacular this morning

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Peter MacPherson @petermacp.bsky.social · 01/05/2025

⚡️New preprint (not peer-reviewed)⚡️ In the SaDAPT trial with people with #HIV and #tuberculosis symptoms in 🇲🇼🇱🇸, we investigated if antiretroviral therapy should be initiated immediately, or delayed until TB results available. ssrn.com/abstract=523... Outcomes (incl. IRIS) similar across both arms.

The front page of the preprint article, showing title and authors

Forest plot showing primary and secondary trial outcomes, with non-inferiority margins

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Peter MacPherson @petermacp.bsky.social · 04/04/2025

Distribution and transmission of #tuberculosis in a high-HIV prevalence city in Malawi: A genomic and spatial analysis 🛟🧪 journals.plos.org/globalpublic... @uofgshw.bsky.social @jasonandrews.bsky.social @rachaelburke.bsky.social @jsalomon.bsky.social

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Peter MacPherson @petermacp.bsky.social · 02/04/2025

New preprint led by @alexandra-richards.bsky.social & @kchorton.bsky.social from @lightontb.bsky.social Eliminating men’s excess risks for #TB & improving access to treatment to comparable rates to women could have major gains for men, women & children. www.medrxiv.org/content/10.1...

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Peter MacPherson @petermacp.bsky.social · 27/03/2025

New publication, led by @rachaelburke.bsky.social In meta-analysis of ~100,000 hospital admission, we found that AIDS-related illnesses (42%) & especially #TB (19%) remain the commonest cause of hospitalisation for people with #HIV, despite high ART coverage. authors.elsevier.com/sd/article/S...

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Peter MacPherson @petermacp.bsky.social · 01/03/2025

Over the last week was privileged to bring together in Blantyre leading #TB scientists & programme managers from Malawi, Zambia, South Africa & UK to kick off new research. But utterly shocked to see the callous and heartless damage being done to patients & communities. @uofgshw.bsky.social

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Peter MacPherson @petermacp.bsky.social · 27/02/2025

Very pleased to be able to contribute to this important work, showing progress towards elimination of mother-to-child transmission of hepatitis B in Africa. @uofglasgow.bsky.social @uofgshw.bsky.social authors.elsevier.com/sd/article/S...

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Peter MacPherson @petermacp.bsky.social · 21/02/2025

🚨New preprint (not yet peer-reviewed)🚨 Identifying advanced #HIV disease supports life-saving treatments. But access to CD4 testing is now really challenging. Unfortunately, clinical staging is not accurate to identify AHD: we need more investment in CD4 testing! papers.ssrn.com/sol3/papers....

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Peter MacPherson @petermacp.bsky.social · 26/01/2025

Have spent this very stormy weekend cooking comfort food and playing board games with the family Vegetable Scotch broth Beef casserole with mashed potatoes and courgette Fettuccine Alfredo (forgot to photo!) Curries #doctorswhocook

A plate of beef casserole, mashed potatoes and courgette

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Peter MacPherson @petermacp.bsky.social · 10/01/2025

Yup - pretty amazing given just how much ice is on the panels. -7 degrees here, so I am seriously impressed.

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

11. Study for Obedience. Sarah Bernstein

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

10. The Sun Walks Down, Fiona McFarlane

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

9. Thicker than Water. Cal Flyn

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

8. Nothing to Envy: Ordinary Lives in North Korea. Barbara Demick

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

6. The Bear and the Nightingale. Katherine Arden

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

4. This Other Eden. Paul Harding

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

For some reason, I struggled to finish quite a few novels this year. So, here is an incomplete brief list of the books I really enjoyed reading in 2024. #booksky 1. Prophet Song. Paul Lynch

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Peter MacPherson @petermacp.bsky.social · 22/12/2024

We urgently need a better, easier-to-use test for #TB infection. We evaluated the QIAreach test among 1049 children and adults in 🇲🇼 Unfortunately, performance was poor & can’t be recommended for use #TBsky #IDSky @hannahrickman.bsky.social doi.org/10.1128/jcm....

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Peter MacPherson @petermacp.bsky.social · 29/11/2024

St Andrew’s day ceilidh with the family at the School of Health & Wellbeing, @uofglasgow.bsky.social

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