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Partnership for Clean Competition @pccantidoping.bsky.social · 09/10/2026

In this article, authors share how blood-based matrices are better suited than urine for detecting certain types of prohibited substances & tracking relevant biomarkers in the Athlete Biological Passport, as well as how matrix selection affects detection & analysis. pubmed.ncbi.nlm.nih.gov/42764756/

The image shows details about the paper linked in the post. It was published in the journal Bioanalysis. The title of the paper is, "From urine to serum: blood-based matrices reshape the future of anti-doping testing."

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Partnership for Clean Competition @pccantidoping.bsky.social · 07/10/2026

Small structural differences in steroids can affect how they are metabolized & detected. Authors compared the metabolism of 2 synthetic steroids (4-CT & 6-CT). Despite differing only in the position of a chlorine atom, they had notably different metabolic profiles. pubmed.ncbi.nlm.nih.gov/42764011/

The image shows details about the paper linked in the post. It was published in the journal Drug Testing and Analysis. The title of the article is, "Metabolic Consequences of Chlorine Position in Testosterone Analogs: A GC-MS Study of C4- Versus C6-Chlorotestosterone Biotransformation."

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Partnership for Clean Competition @pccantidoping.bsky.social · 05/10/2026

This review article examines innovations & advances in microsampling techniques, technologies, sample preparation, and analyses. These include microsampling devices used in anti-doping testing and use of new analytical workflows to detect protein & peptide doping agents. pubs.rsc.org/ay/article/d...

The image shows details about the article linked in the post. It was published in the journal Analytical Methods. The title of the article is, "Microsampling of proteins from biological matrices: sampling methods and devices, typical workflows, clinical examples, novel applications and innovations."

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Partnership for Clean Competition @pccantidoping.bsky.social · 01/10/2026

Authors developed methods to detect the synthetic peptide retatrutide & reported on excretion profiles in plasma & urine. It was only detectable in plasma & had a long detection window (~50 days). This shows plasma is a suitable matrix for retatrutide detection. pmc.ncbi.nlm.nih.gov/articles/PMC...

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Partnership for Clean Competition @pccantidoping.bsky.social · 30/09/2026

We're excited to share findings from Dr. John Eiler's PCC-funded research. He developed an orbitrap-based mass spectrometry method that provides multidimensional isotope fingerprints. The approach could help identify the sources of steroids in anti-doping samples. pubmed.ncbi.nlm.nih.gov/42752109/

The image shows details about the paper linked in the post. It was published in the journal Analytical Chemistry. The title of the article is, "Fragment-Resolved Carbon and Hydrogen Isotope Analysis of Urinary Steroids by Orbitrap Mass Spectrometry."

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Partnership for Clean Competition @pccantidoping.bsky.social · 29/09/2026

Steroids have long been banned in sport, but the risks of using them go beyond sitting out from competition. Dr. Aaron Baggish discussed the long-term consequences of doping and why doing it with medical supervision doesn’t necessarily make it safer. cleancompetition.org/anti-doping-podcast/181

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Partnership for Clean Competition @pccantidoping.bsky.social · 25/09/2026

Researchers developed & validated methods to detect testosterone & its metabolites using supercritical fluid chromatography that expedite separation & evaporation steps. Results using the new method were comparable to those obtained via common HPLC-based procedures. pubmed.ncbi.nlm.nih.gov/42764208/

The image shows details about the article linked in the post. It was published in the journal Drug Testing and Analysis. The title of the article is, "Supercritical Fluid Chromatography for Expedited Sample Clean-Up in Isotope Ratio Mass Spectrometry Including Cholesterol as New Endogenous Reference Compound."

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Partnership for Clean Competition @pccantidoping.bsky.social · 24/09/2026

The PCC is heading to Chattanooga for the 2026 Science Symposium hosted by one of our founding members, USADA. We’re looking forward to a weekend full of updates, findings, and real-world anti-doping applications from top labs and researchers globally. Learn more: www.usada.org/science-rese...

This is a screenshot from the link in the post. It shows the Science and Research page of the USADA website.

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Partnership for Clean Competition @pccantidoping.bsky.social · 21/09/2026

Authors review anti-doping applications of mass spectrometry, particularly advanced platforms. They also examine studies to date on microsampling, microextraction, and other sample pretreatment approaches. This may help labs choose methods that best fit their needs. pubmed.ncbi.nlm.nih.gov/42609009/

The image shows details about the paper linked in the post. It was published in the journal Critical Reviews in Analytical Chemistry. The title of the article is, "Mass Spectrometry-Based Anti-Doping Analysis: A Critical Review of Emerging Analytical and Sample Pretreatment Strategies."

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Partnership for Clean Competition @pccantidoping.bsky.social · 18/09/2026

Authors tested the reproducibility of serum androgen profiles in 5,500+ samples from 1,600+ elite athletes. Their data provide insights into the expected variability of serum T, DHT, A4, and their ratios. This may help identify abnormal variations in the ABP. 🚫💊 🧪 pubmed.ncbi.nlm.nih.gov/42374920/

The image shows details about the article linked in the post. It was published in the journal Drug Testing and Analysis, and the title of the article is, "Reproducibility of Serum Androgen Concentrations by Liquid Chromatography Mass Spectrometry in Healthy Male and Female Athletes."

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Partnership for Clean Competition @pccantidoping.bsky.social · 16/09/2026

Authors developed and validated highly sensitive methods to detect T-esters in urine sample. With this approach, doping with exogenous testosterone can be directly identified using just urine samples. This is especially valuable if a blood sample was not collected. pubmed.ncbi.nlm.nih.gov/42309655/

The image shows details about the paper linked in the post. It was published in the journal Drug Testing And Analysis. The title of the paper is, "Detection of Testosterone Esters in Urine: Evidence of Trace-Level Detectability in Doping Control Samples."

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Partnership for Clean Competition @pccantidoping.bsky.social · 15/09/2026

He shared promising preliminary findings from this work, important limitations, and how these kinds of models could continue to enhance anti-doping analyses in the future. Listen to the full episode here: cleancompetition.org/anti-doping-... #science #podcast #antidoping #machinelearning #plasma

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Partnership for Clean Competition @pccantidoping.bsky.social · 11/09/2026

What challenges & questions remain in anti-doping social sciences research? Authors critically examine the state of the science & consider steps towards meaningful progress. They advocate for further research capacity-building, diversifying models, & other changes. pubmed.ncbi.nlm.nih.gov/41371322/

The image shows details about the article linked in the post. It was published in the journal Psychology of Sport and Exercise. The title of the article is, "Progress or performance in anti-doping (social science) research? A critical reflection on achievements and future directions."

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Partnership for Clean Competition @pccantidoping.bsky.social · 09/09/2026

Troponin activators are prohibited at all times in sport. Authors developed a rapid, simple, sensitive, and reliable method to screen for 6 troponin activators using dried urine spots. The dried urine spot samples had higher long-term stability versus liquid urine. pubmed.ncbi.nlm.nih.gov/42447638/

The image provides details about the paper linked in the post. It was published in the Journal of Chromatography A. The title of the paper is, "Dried urine spot strategy coupled with UHPLC-MS/MS for the analysis of troponin activators."

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Partnership for Clean Competition @pccantidoping.bsky.social · 04/09/2026

Authors used advanced analytic techniques to identify an unknown compound found in a supplement purchased online. The compound was identified as 6-BrAED, a designer steroid that is prohibited at all times as a non-approved substance. analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

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Partnership for Clean Competition @pccantidoping.bsky.social · 02/09/2026

Increasing efficiency, cost-effectiveness, sensitivity, specificity, & sustainability are key goals in anti-doping. In line with these goals, authors successfully applied the Bar Adsorptive MicroExtraction method to identify cocaine and 3 metabolites in human urine. www.nature.com/articles/s41...

The image shows details about the article linked in the post. It was published in the journal Scientific Reports. The title of the article is, "Bar adsorptive microextraction for the qualitative detection of cocaine and its metabolites in urine for anti-doping control."

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Partnership for Clean Competition @pccantidoping.bsky.social · 01/09/2026

Kara also plans to build upon existing HRMS methods to improve specificity and sensitivity. She is a professor at the University of California San Francisco and a recipient of PCC funding. Listen to the full episode here: cleancompetition.org/anti-doping-...

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Partnership for Clean Competition @pccantidoping.bsky.social · 31/08/2026

Anti-doping requires contributions from many experts. Drs. Susan Backhouse & Laurie Patterson describe how psychological research has enhanced our understanding of doping in sport. They describe scientific advances, challenges, & areas for future research. 🚫💊 🧪 www.sciencedirect.com/.../pii/S146...

The image shows details about the article linked in the text. It was published in the journal Psychology of Sport and Exercise. The title of the article is, "Bridging research and practice in the psychology of doping in sport: Reflections and future directions."

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Partnership for Clean Competition @pccantidoping.bsky.social · 28/08/2026

To avoid doping detection, synthetic urine may be substituted or used to dilute an authentic sample. Authors examined approaches to detect synthetic urine. All approaches flagged pure synthetic urine. In particular, EA-IRMS could complement anti-doping analyses. pubmed.ncbi.nlm.nih.gov/42312799/

This image shows details about the paper linked in the post. It was published in the journal Drub Testing And Analysis. The title of the paper is, "Identification of Synthetic Urine by Analysis of Stable Carbon and Nitrogen Isotope Ratios and Comparison to Established GC-MS/MS and LC-MS/MS Analysis."

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Partnership for Clean Competition @pccantidoping.bsky.social · 27/08/2026

The following article by the International Paralympic Committee (IPC) shares some other exciting highlights to look out for on the road to LA28. Read the full article here: bit.ly/4zGmgDZ #LA28 #RoadtoLA #ParaSport #Paralympics

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Partnership for Clean Competition @pccantidoping.bsky.social · 26/08/2026

Multi-step sample preparation and analysis workflows add time and cost to anti-doping analyses. Researchers developed and validated a rapid, streamlined, and harmonized workflow for the detection of 54 prohibited substances in dried blood spots, serum, and plasma. 🚫💊 🧪 pubs.rsc.org/an/article-a...

The image provides detail about the paper linked in the post. It was published in the journal Analyst. The title of the paper is, "Rapid and harmonized analytical workflow for the determination of peptidic and non-peptidic doping agents in dried and liquid blood matrices."

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Partnership for Clean Competition @pccantidoping.bsky.social · 24/08/2026

If you missed the deadline for this round, LOIs for our spring application cycle will open on September 2 and are due February 1. Full applications can be submitted using the link below. Submit your application here: proposalcentral.com

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Partnership for Clean Competition @pccantidoping.bsky.social · 21/08/2026

In #antidoping samples, it can be difficult to distinguish steroids with similar molecular structures. Authors showed how cryogenic gas-phase infrared spectroscopy can identify & distinguish steroids with very similar structures when an ion mobility approach could not. pubs.acs.org/amachv/artic...

The image shows details about the paper linked in the post. It was published in the journal Measurement Science, and the title of the article is, "Steroid Fingerprinting with Cryogenic Gas-Phase Infrared Spectroscopy."

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Partnership for Clean Competition @pccantidoping.bsky.social · 19/08/2026

Blood doping is especially hard to detect in homogeneous populations. Scientists made a tailored panel for antigen markers from red blood cells & platelets that detected simulated transfusion scenarios. Population-specific panels may improve blood doping detection. pubmed.ncbi.nlm.nih.gov/42338234/

The image shows details about the paper linked in the post. It was published in the journal Drug Testing and Analysis. The title of the article is, "Exploring the Potential of Population-Optimized Red Blood Cell Antigens and Platelet HLA Typing for Homologous Blood Transfusion Detection in Japanese Athletes."

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Partnership for Clean Competition @pccantidoping.bsky.social · 18/08/2026

Adam's story highlights the importance of keeping the athlete experience at the center of anti-doping policies and practices. Listen to the full episode here: cleancompetition.org/anti-doping-...

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Partnership for Clean Competition @pccantidoping.bsky.social · 17/08/2026

This is the 1st report of quantitative excretion data for the M5-b long-term metabolite of LGD-4033 w/ micro-dose conditions. Authors examined excretion for 1-5 day administration at 3 doses, providing valuable evidence for interpreting adverse analytical findings. pubmed.ncbi.nlm.nih.gov/42547066/

The image shows details about the paper linked in the post. It was published in the journal Drug Testing and Analysis. The title of the paper is, "Quantification of the Carboxylated LGD-4033 Long-Term Metabolite in Human Micro-Dose Excretion Study Urine Samples."

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Partnership for Clean Competition @pccantidoping.bsky.social · 14/08/2026

The cost of #antidoping analyses is a challenge. Authors made a low-cost electrochemical platform to screen for the prohibited steroid danazol. It was effective in spiked water & synthetic urine/saliva. Future work can validate it & assess potential applications. pubmed.ncbi.nlm.nih.gov/42494320/

The image shows details of the article linked in the post. It was published in the journal Analytical Methods. The title of the article is, "A low-cost electrochemical screening platform for danazol in anti-doping analysis."

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Partnership for Clean Competition @pccantidoping.bsky.social · 12/08/2026

National anti-doping organizations (NADOs) are key players in the global fight against doping. European NADO leaders shared insights on their challenges & strategic needs. The findings can inform the new anti-doping policies & capacity-building efforts. pubmed.ncbi.nlm.nih.gov/42311486/

This image shows details of the article linked in the post. It was published in the journal Frontiers in Sports and Active Living, and the title is, "Strategic priorities and barriers to an effective anti-doping programme: views and opinions of European NADO leaders."

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Partnership for Clean Competition @pccantidoping.bsky.social · 10/08/2026

Authors compared measurements of 2 steroids using GC-qTOF and LC-MS/MS. They showed good agreement, but failure to reach WADA's LOQs highlight a need for clearer acceptance criteria for use of HRMS approaches to identify substances. analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...

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Partnership for Clean Competition @pccantidoping.bsky.social · 07/08/2026

Collecting venous blood for anti-doping testing is more invasive & requires trained personnel. Authors examined ABP hematological markers from venous vs liquid capillary blood & found liquid capillary blood could serve as an alternative for most hematological markers. www.ovid.com/10.1249/MSS....

The image shows details about the paper linked in the post. It was published in the journal Medicine & Science in Sports & Exercise. The title of the paper is, "Capillary Blood as a Potential New Matrix for the Athlete Biological Passport: A Field-Based Comparison Study."

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Partnership for Clean Competition @pccantidoping.bsky.social · 06/08/2026

Pre-applications are now closed, and full applications are open. If you submitted a pre-application for a research grant or fellowship, be sure to complete your full application by September 1 to be considered for this round of funding. Submit yours here: proposalcentral.com

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Partnership for Clean Competition @pccantidoping.bsky.social · 05/08/2026

How athletes & DCOs perceive remote sampling is important for wider adoption of remote testing. In this PCC-funded work, authors asked athletes & DCOs about transparency, trust, perceived benefits, risk, perceived legitimacy, & their attitude toward remote sampling. pubmed.ncbi.nlm.nih.gov/42453616/

The image shows details about the paper linked in the post. It was published in the journal Frontiers in Sports and Active Living. The title of the article is, "When they don't come around: how athletes and DCOs perceive the legitimacy of a remote sampling system in anti-doping testing."

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Partnership for Clean Competition @pccantidoping.bsky.social · 04/08/2026

She shared some of her best tips and practices that could help anyone looking to broaden the reach of their research. Listen to the full episode here: cleancompetition.org/anti-doping-... #science #antidoping #podcast #research #results #sciencecommunication

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Partnership for Clean Competition @pccantidoping.bsky.social · 03/08/2026

RNA-based biomarkers like messenger RNAs and microRNAs have shown promise as complementary tools for the Athlete Biological Passport. This article reviews studies on RNA-based biomarkers, methods of measurement, and important considerations for implementation. www.sciencedirect.com/science/chap...

The image shows details about the paper linked in the post. It was published in the journal Advances in Clinical Chemistry. The title of the paper is, "RNA biomarkers in antidoping."

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Partnership for Clean Competition @pccantidoping.bsky.social · 31/07/2026

Distinguishing out-of-competition MP use & permitted administration in competition from prohibited use is important. Authors examined MP urinary excretion profiles after oral administration & found the washout period & urinary MRL are appropriate to detect oral use. pubmed.ncbi.nlm.nih.gov/42343043/

This image shows details about the article linked in the post. It was published in the journal Clinical Pharmacokinetics, and the title of the article is, "Revisited Pharmacokinetic Profiles of Methylprednisolone in Plasma and Urine After Single and Multiple Oral Administrations: Relevance in Sports Drug Testing."

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Partnership for Clean Competition @pccantidoping.bsky.social · 30/07/2026

While there are many benefits to using dried blood spot sampling in anti-doping, analyses are limited by the small amount of sample available. To get the most out of a dried blood spot sample, authors developed & validated a method that detects 91 target compounds. pubmed.ncbi.nlm.nih.gov/42345615/

The image shows details about the paper linked in the post. It was published in the journal Biomedical Chromatography. The title of the article is, "Dried Blood Spots for Doping Purpose-Two-Step Protocol for Analysis of Non-Threshold Substances and Anabolic Steroid Esters From One Spot/Pebble."

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Partnership for Clean Competition @pccantidoping.bsky.social · 29/07/2026

Reported doping prevalence rates vary across studies, & using indirect estimation models involves complex methods & modeling assumptions. Authors discuss developments, challenges, & trends in the field for applying indirect estimation models to doping prevalence. pmc.ncbi.nlm.nih.gov/articles/PMC...

This image shows details about the article linked in the post. It was published in the journal Sports (Basel). The title of the article is, "Charting the Scientific Landscape of Indirect Estimation Models in Doping Prevalence Research: A Bibliometric Analysis with Narrative Appraisal."

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Partnership for Clean Competition @pccantidoping.bsky.social · 27/07/2026

Don’t forget to submit your pre-application for a research grant or fellowship by August 1. Our pre-applications are now hosted on Altum and can be accessed through the link below.

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Partnership for Clean Competition @pccantidoping.bsky.social · 23/07/2026

We’re proud to contribute to the next generation of scientists who will continue to push the boundaries of anti-doping research. For more information, visit our website and be sure to submit your pre-application by August 1st. cleancompetition.org/programs/fel...

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Partnership for Clean Competition @pccantidoping.bsky.social · 22/07/2026

Estimating doping prevalence is complex, & scientists developed different models to overcome challenges. Authors reviewed studies using indirect estimation models to examine the prevalence of doping in competitive & recreational athletes in 1 or multiple sports. link.springer.com/article/10.1...

The image shows details about the paper linked in the post. It was published in the journal Sports Medicine - Open. The title of the article is, "Doping Prevalence in Sport from Indirect Estimation Models: A Systematic Review and Meta-analysis."

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Partnership for Clean Competition @pccantidoping.bsky.social · 21/07/2026

The Milan-Cortina Games saw 63% of athletes tested during competition. PCC Founding Members the U.S. Anti-Doping Agency and the United States Olympic & Paralympic Committee are hard at work with organizations around the world to keep this momentum rolling into #LA28.

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Partnership for Clean Competition @pccantidoping.bsky.social · 20/07/2026

Researchers developed a rapid, sensitive, and reliable high-performance liquid chromatography-mass spectrometry method to detect 7 troponin activators in urine and serum. Their results suggest this approach could be useful for routine #antidoping analyses. www.sciencedirect.com/science/arti...

This image shows details about the paper linked in the post. It was published in the Journal of Chromatography B, and the title of the paper is, "Validation of an HPLC-MS method for simultaneous determination of seven troponin activators in human urine and serum for doping control."

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Partnership for Clean Competition @pccantidoping.bsky.social · 17/07/2026

The PCC was pleased to provide funding to support this research examining how athletes & Doping Control Officers perceive remote sampling in anti-doping. Authors share actionable recommendations for anti-doping organizations to pilot new remote sampling protocols. www.frontiersin.org/journals/spo...

The image provides details about the article linked in the post. It was published in the journal Front. Sports. Act. Living, and the title of the article is, "Exploring the perceptions of athletes and DCOs on the remote sampling procedure in anti-doping testing: shifting control to burden."

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Partnership for Clean Competition @pccantidoping.bsky.social · 15/07/2026

Athlete Support Personnel (ASP) can have major impacts on the behaviors athletes engage in & decisions they make. Research shows different ASP types influence different doping-related behaviors, suggesting a need for stronger role-specific anti-doping education. pmc.ncbi.nlm.nih.gov/articles/PMC...

This image shows details about the paper linked in the post. It was published in the journal Healthcare (Basel). The title of the paper is, "The Role of Athlete Support Personnel in Anti-Doping: A Narrative Review of Contemporary Evidence."

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Partnership for Clean Competition @pccantidoping.bsky.social · 14/07/2026

He also shared how the organization collaborates with partners, brands, and other stakeholders to prevent and catch doping in athletics. Listen to the episode here: cleancompetition.org/anti-doping-... #antidoping #science #research #athletics #integrity #dopingdetection

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Partnership for Clean Competition @pccantidoping.bsky.social · 10/07/2026

Former PCC Fellow Dr. Sara Solheim is working to identify and address confounding factors in ABP analysis and interpretation. For more details on her research, listen to our interview with her in our recent podcast episode linked below. Listen here: bit.ly/4xO2G7Y

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Partnership for Clean Competition @pccantidoping.bsky.social · 09/07/2026

Our Fellowship and Research Grant pre-application deadline is quickly approaching. Submit your proposal by August 1 using the link below. PCC grant applications are now hosted on Altum. Visit our website for help accessing or creating your profile. proposalcentral.com

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Partnership for Clean Competition @pccantidoping.bsky.social · 06/07/2026

Authors examined the urinary & plasma excretion profiles of DEF & its metabolites after one oral administration. They identified the metabolite DES as the best marker for urinary detection. The results support WADA's MRL of 30 ng/mL & suggested 3-day washout period. pubmed.ncbi.nlm.nih.gov/42155981/

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Partnership for Clean Competition @pccantidoping.bsky.social · 30/06/2026

Congratulations to Scientific Advisory Board member, Dr. Gary Green, on his induction into the Southern California Jewish Sports Hall of Fame! Dr. Green joins more than 300 other esteemed individuals who have created a positive impact on the sports landscape in Southern California.

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Partnership for Clean Competition @pccantidoping.bsky.social · 25/06/2026

Don’t forget to submit your pre-application by August 1 for our next round of funding. Applications are now hosted on Altum and can be accessed through the link below. Visit the Application Center on our website for help setting up or accessing your account. t.co/uKDJ2t6b2y

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