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Paul Young

@paulgyoung.bsky.social
570 followers 561 following 1 posts

MD-PhD student at Tri-I. PhD candidate in Jue Chen’s lab @Rockefeller. I like to appreciate the little things (membrane protein biophysics and structural bio).

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Reposted by Paul Young
Tristan Yates @tristansyates.bsky.social · 16/09/2025
How does spontaneous memory reinstatement at rest relate to episodic memory during development? And how do early experiences influence neural mechanisms of episodic memory encoding and reinstatement? New preprint! www.biorxiv.org/content/10.1...
biorxiv.org
Spontaneous reinstatement of episodic memories in the developing human brain
The hippocampus supports episodic memories in development, and yet how the brain stabilizes these memories determines their long-term accessibility. This study examined how episodic memories formed in...
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Paul Young @paulgyoung.bsky.social · 02/08/2025
Happy to have this work out! Using cryo-EM and electrophysiology, we clarify the mechanism of a small molecule inhibitor of CFTR that could have some important clinical applications. rdcu.be/eyVyq
rdcu.be
Structure of CFTR bound to (R)-BPO-27 unveils a pore-blockage mechanism
Nature Communications - Hyperactivation of the cystic fibrosis transmembrane conductance regulator (CFTR) is central to the pathogenesis of secretory diarrheas and autosomal dominant polycystic...
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Reposted by Paul Young
Sami Yousif @samiyousif.bsky.social · 25/06/2025
I have noticed that many cool people are starting labs at Ohio State right now. I've decided to follow their lead. Soon, my lab will be moving to Ohio State as well. You can learn more about our recent and upcoming work here: www.cogdevlab.org
cogdevlab.org
PCDL @ OSU
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Reposted by Paul Young
Brynn Sherman @brynnsherman.bsky.social · 24/06/2025
Incredibly excited and grateful to share that I’ll be starting a lab at The Ohio State University this(!) fall! My lab will study human learning and memory, with related interests in sleep, stress, and time perception. More info soon, but do get in touch if you’re interested in joining!
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Reposted by Paul Young
Tristan Yates @tristansyates.bsky.social · 20/03/2025
Why do we not remember being a baby? One idea is that the hippocampus, which is essential for episodic memory in adults, is too immature to form individual memories in infancy. We tested this using awake infant fMRI, new in @science.org #ScienceResearch www.science.org/doi/10.1126/...
science.org
Hippocampal encoding of memories in human infants
Humans lack memories for specific events from the first few years of life. We investigated the mechanistic basis of this infantile amnesia by scanning the brains of awake infants with functional magne...
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Reposted by Paul Young
Tristan Yates @tristansyates.bsky.social · 11/03/2025
We will keep fighting and standing up for science.
Protest sign with black text listing a subset of words that were flagged for further scrutiny by federal agencies (including “bias” “increase diversity” “disability” “racism” “trauma” “victim” and “women”). In large red letters over top, the words “These words kill fascists” is written, an homage to Woody Guthrie.
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Reposted by Paul Young
Tristan Yates @tristansyates.bsky.social · 11/03/2025
I am grateful that right now I am part of a very supportive community — though at the same time, it is painful to know that I’m not alone.
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Reposted by Paul Young
Tristan Yates @tristansyates.bsky.social · 11/03/2025
Last year, I was overjoyed to receive an NIH NRSA fellowship to study toddler brains and caregiving effects on memory at Columbia. Last night, my grant was terminated.
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