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Paula Morales

@paulamlcr.bsky.social

20 followers 62 following 0 posts

#GPCRs #cannabinoids #MedChem #DrugDiscovery

Posts Replies Media

Reposted by Paula Morales

IQMB_CSIC @iqm-csic.bsky.social · 26/02/2026

Nuestra compañera @paulamlcr.bsky.social ha liderado un estudio que identifica ligandos capaces de modular simultáneamente los receptores CB2R y M1R, una estrategia prometedora para abordar trastornos neurodegenerativos complejos como Alzheimer o Parkinson. 📄 Paper 👉 bit.ly/4b9HNLa #Cannabinoids

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Reposted by Paula Morales

Hospital del Mar Research Institute @researchmar.bsky.social · 10/12/2024

📢 #Hiring! PhD in #Bioinformatics? Join the GPCR Drug Discovery Group at @hmar_research ➡️Manage the GPCRmd web server ➡️Develop tools for GPCR research ➡️Integrate MD data into models 👩‍🔬GPCR biology, Python, ML, web dev (HTML/JS/Flask) Apply now! 👉 www.imim.es/ofertes/en_d...

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Reposted by Paula Morales

Yazan J. Meqbil @yazmeq.bsky.social · 21/11/2024

Another day, another excellent database. I’ve been an avid and grateful user of GPCRdb, GPCRmd, and other databases, all of which keep getting better. I’m excited to try this one! academic.oup.com/nar/advance-...

academic.oup.com

PGxDB: an interactive web-platform for pharmacogenomics research

Abstract. Pharmacogenomics, the study of how an individual's genetic makeup influences their response to medications, is a rapidly evolving field with sign

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Reposted by Paula Morales

EFMC @euromedchem.bsky.social · 07/01/2025

🏆 YSN-YMCC Grants 2024 - Applications Reminder! 📢 Two grants offered by the EFMC-YSN and the ACSMEDI-YMCC for attending the ACSMEDI | EFMC Medicinal Chemistry Frontiers in Chicago, USA, on May 12-15, 2025.✨ Check out the eligibility criteria and apply now: buff.ly/4fCJhgX

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Reposted by Paula Morales

Martin Vögele @martinvoegele.bsky.social · 02/12/2024

New #GPCR preprint by Schmidt et al. shows that amphipathic helix 8 plays a key role in guiding receptors to regions of high membrane curvature, ultimately facilitating their endocytosis.

biorxiv.org

Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs

Cellular signaling relies on the activity of transmembrane receptors and their presentation on the cellular surface. Their continuous insertion in the plasma membrane is balanced by constitutive and a...

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