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Sierra Palumbos

@palumbos.bsky.social
300 followers 537 following 13 posts

Cellular neuroscientist. Postdoc in Holzbaur lab. Educator. Asking what neurons do with their trash. sierrapalumbos.com

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Sierra Palumbos @palumbos.bsky.social · 07/07/2025
Very excited to share my postdoc work- out now at PNAS! Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
pnas.org
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
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Diana Voss @dianavoss.bsky.social · 18/02/2025
This is going to hurt science. 🧪 What hurts science hurts healthcare. 🩺 What hurts healthcare hurts you. 🫵 Call, email, and if possible visit, your representatives. This is personal whether you want it to be or not.
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Jeremy Berg @jeremymberg.bsky.social · 11/02/2025
Very good source to understand indirect costs by Sally Rockey, former Deputy Director for Extramural Activities at NIH. Very thorough and clear. If you want to understand indirect costs or have family or friends who are pestering you to explain IDC, send them this... www.aau.edu/key-issues/i...
aau.edu
Indirect Costs 101, Sally J. Rockey | Association of American Universities (AAU)
Sally Rockey, explains indirect costs and how they support research.
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Rick Huganir @rhuganir.bsky.social · 07/02/2025
This is the end of science as we know it if it stands—15% IDCs for all NIH Grants. grants.nih.gov/grants/guide...
grants.nih.gov
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
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David F. Warner @dwarnersoc.bsky.social · 07/02/2025
⚠️ Effective Monday 2/10/25, NIH indirect rate capped at 15%. Applies to existing & future grants. —> Deep budget cuts & program closures coming to a university near you. Is this the break the glass moment for university administrators who have been silent so far about the attack on science?
grants.nih.gov
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
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Sierra Palumbos @palumbos.bsky.social · 06/02/2025
Revised and Extended: What's Happening Inside the NIH and NSF | Science | AAAS www.science.org/content/blog...
science.org
Revised and Extended: What's Happening Inside the NIH and NSF
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mito911 @mito911.bsky.social · 29/01/2025
Shout out to Dr. Bishal Basak in @erikaholzbaur.bsky.social at @upenn.bsky.social for spearheading the work on identifying a new stress response pathway that regulates mitophagy in neurons! ➡️Read pre-print here: doi.org/10.1101/2024...
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Meng-meng Fu @mengmengfu.bsky.social · 24/01/2025
If you’re a federal govt employee targeted for leave or termination on the basis of your DEI work, please file an EEO (Equal Employment Opportunity) complaint & retain legal counsel. I’m a former NIH PI. Happy to refer you to a law firm that has successfully sued the govt many times! Pls repost 🙏❤️
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Zoe McElligott @nanopharmnc.bsky.social · 22/01/2025
I just reached out to my senators about the NIH situation. If you need to find out how much impact NIH has in your state in terms of dollars in and their economic impact here's a link: www.unitedformedicalresearch.org/nih-in-your-...
unitedformedicalresearch.org
NIH In Your State - United For Medical Research
Select a state on the map to see the impact of NIH funding across America.
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christine liu / two photon art @christineliu.art · 22/01/2025
Step 1) find your rep www.congress.gov/members/find... Step 2) send an email or call their office Step 3) tell them that federal spending on scientific advancement is the best hope we have to “win against china” or whatever these guys are obsessed with these days
congress.gov
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Carl T. Bergstrom @carlbergstrom.com · 22/01/2025
Study sections are the review panels that allocate NIH research grants. They bring in experts from around the country and have to be scheduled many months in advance; they provide the funds that keep the nation's biomedical research going. It's hard to overstate the disruption this causes.
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Jane Liebschutz, MD MPH (she/her) @liebschutz.bsky.social · 22/01/2025
All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.
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Abby Polter @ampolter.bsky.social · 23/01/2025
The United States built a publicly funded scientific enterprise that worked miracles. We went to the moon and mars, laid the groundwork for computing revolutions, turned AIDS from a death sentence to a chronic condition, drastically cut cancer deaths. And now we're just going to dismantle it?
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Aafke Gros @aafkegros.bsky.social · 15/01/2025
Microscopy Nodes is now up on bioRxiv! 🚀 This is a Blender extension that seamlessly integrates and visualizes 3D microscopy data (TIF & @zarr.dev). High-quality volume rendering for anyone, in both EM and fluorescence, regardless of computational expertise! 🔬 www.biorxiv.org/content/10.1...
FIB-SEM dataset visualized with Microscopy Nodes, data from Mocaer et al 2023
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mito911 @mito911.bsky.social · 25/11/2024
📣Now that @mito911.bsky.social is on Bluesky, let's highlight the research run in our team! Check out the pre-print by @palumbos.bsky.social Palumbos et al. and colleagues from the @erikaholzbaur.bsky.social! @asapresearch.bsky.social ⬇️
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mito911 @mito911.bsky.social · 25/11/2024
Read the recent pre-print by @palumbos.bsky.social now on BioRxiv. In the meanwhile, find below and read a thread for a sweet preview of her work! 👩‍🔬 🧫 @asapresearch.bsky.social
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Namnezia 🥑 @namnezia.bsky.social · 20/11/2024
Do you teach neuroscience? Here’s a list I’ve compiled of mostly free online neuroscience textbooks, simulations and datasets you can use for your course! If I’m missing something, let me know so I can add it! docs.google.com/document/d/1...
docs.google.com
Free Neuroscience Textbooks and Online Tutorials
Free Neuroscience Textbooks and Online Tutorials (Compiled by Carlos Aizenman, Brown University, Dept. of Neuroscience) Maintaining a current list of digital educational resources is tricky. Softwar...
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Juan S. Bonifacino @juanbonifacino.bsky.social · 17/11/2024
Here are some free/open-source sites for the preparation of scientific illustrations, including icon libraries: bioicons.com, scidraw.io, bioart.niaid.nih.gov, inkscape.org, biogdp.com, reactome.org/icon-lib
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mito911 @mito911.bsky.social · 15/11/2024
If you are interested in mitochondria, mitophagy and/or PD follow the mito911 Webinar series! Events calendar and registration at this link parkinsonsroadmap.org/events/
parkinsonsroadmap.org
Events
Aligning Science Across Parkinson’s (ASAP) aims to foster collaboration and discovery by supporting virtual and in-person events that facilitate connections and provide an avenue for sharing ideas. Se...
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Nick Smith @neuronnick.bsky.social · 15/11/2024
Just going in to lab hoping no one in Congress notices me feeding mice little sweet treats to see if they really want it or just merely like it
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Erika Holzbaur-Howland @erikaholzbaur.bsky.social · 13/11/2024
Excited to share this new preprint from Sierra Palumbos, tracking the effects of dysfunctional autophagy in neurons: www.biorxiv.org/content/10.1...
biorxiv.org
Autophagic stress activates distinct compensatory secretory pathways in neurons
Autophagic dysfunction is a hallmark of neurodegenerative disease, leaving neurons vulnerable to the accumulation of damaged organelles and proteins. However, the late onset of diseases suggests that ...
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Erika Holzbaur-Howland @erikaholzbaur.bsky.social · 15/11/2024
So proud of Adam Fenton and his work defining the role of FMRP in the local regulation of mitochondrial fission in neurons via local translation: www.nature.com/articles/s41...
nature.com
FMRP regulates MFF translation to locally direct mitochondrial fission in neurons - Nature Cell Biology
Fenton et al. show that FMRP granules dock at the mitochondrial midzone in a Rab7-dependent manner in axons and dendrites, where they promote local MFF synthesis and fission at the mitochondrial midzo...
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Sierra Palumbos @palumbos.bsky.social · 15/11/2024
Happy to be here and excited to share my postdoc work, "Autophagic stress activates distinct compensatory secretory pathways in neurons" Now on BioRxiv www.biorxiv.org/content/10.1... Many thanks to @erikaholzbaur.bsky.social and @asapresearch.bsky.social
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