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PacBio

@pacbio.bsky.social
5.8K followers 12K following 850 posts

Our mission is to enable the promise of genomics to better human health by creating the world’s most advanced sequencing technologies.

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PacBio @pacbio.bsky.social · 4h
From long reads to new discoveries! 🇸🇪 Join Somar Al-Walai at #LRUA2026 on Mon 2 Nov, 10:50, for the latest from PacBio, including how Revio and Vega are bringing HiFi sequencing to more labs. Want to connect with our team? Book a 1:1 meeting in Uppsala: bit.ly/4yN4sGM
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PacBio @pacbio.bsky.social · 15/10/2026
Repeat expansions. Mosaicism. Methylation. One PCR-free workflow. 🎯 PacBio PureTarget uses HiFi sequencing to characterize challenging genes such as FMR1, C9orf72 & SMN1, capturing repeat length, sequence & methylation without amplification. Read more: bit.ly/4i6hyaZ
A graphic with a stylized letter "P" at the center against a purple background. Surrounding the "P" are sections titled "Copy number variation," "Structural variants," "Extreme sequence context," and "Tandem repeats," each with gene names underneath: "TNXB, GBA, CYP21A2, SMN1/2," "HBA1/2, F8," "RPGR," and "FMR1, FXN, AFF2, RAX." Below the "P" is the phrase, "All in one assay.
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PacBio @pacbio.bsky.social · 15/10/2026
Clinical targeted sequencing is evolving. 🧬 Vega SPRQ-Nx makes HiFi sequencing more accessible with higher data output, lower DNA input & faster runs. Explore applications in repeat expansions, HLA typing & more. Download the HiFi Playbook: bit.ly/4wTy43t
The image is a promotional graphic for PacBio's SPRQ-Nx on the Vega system, highlighting "HiFi for targeted sequencing." It mentions a new guide for sample preparation, sequencing, and analysis. The image features icons for workflow examples, automation tips, and an overview of the Vega SPRQ-Nx. A pink machine labeled "Vega" and a matching guidebook are shown.
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PacBio @pacbio.bsky.social · 14/10/2026
New preprint from the Quake lab at Stanford University! 🔬 Using Kinnex on Revio, researchers mapped 203,311 single cells across 26 human tissues, finding 37.6% of transcript structures were novel. Read the preprint: bit.ly/4jh6muf Explore Kinnex 16-fold: bit.ly/4APmLfM
Informational graphic titled "New Preprint" featuring details about a full-length isoform atlas of 26 human tissues by Quake lab, Stanford University, and Chan Zuckerberg Biohub. Highlights include "37.6% of transcript structures are novel," based on 854,410 detections, and "203,311 single cells from 12 Tabula Sapiens donors." It also mentions "144 cell types" and references the Kinex single-cell RNA kit on the PacBio Revio system. The research is by Mantri et al. and is available on bioRxiv, not yet peer-reviewed.
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PacBio @pacbio.bsky.social · 13/10/2026
Now available! Explore HiFi sequencing for biopharma & biotech R&D. 🔬 Hear from industry experts about applications in drug discovery, gene editing, vector characterization, mRNA & antibody therapeutics, and agricultural research. Register to access the webinar: bit.ly/3TYfwBr
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PacBio @pacbio.bsky.social · 13/10/2026
Just one week until #ASHG26 in Montréal! 🇨🇦 Visit #PacBio at booth #605 to meet our scientists, see Revio & Vega in action, and explore how HiFi sequencing is advancing human genomics. Plan your visit and explore our full program: bit.ly/3TDejiN
Bold text reads '1 Week Until ASHG 2026! Connect with us at PacBio booth 605' on a pink background with abstract patterns.
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PacBio @pacbio.bsky.social · 12/10/2026
PacBio President and CEO, Mark Van Oene, spoke to GenomeWeb about our new partnership with TychoBio. TychoBio plans to use PacBio HiFi sequencing on 10,000+ samples to generate data for AI models designed for RNA therapy development. Read more here: bit.ly/4rO7bgc
This image is a GenomeWeb article titled "Pacific Biosciences, TychoBio Partner on AI Models for RNA Therapies." It includes a quote: "AI can speed up RNA therapy design, but only if it learns from high-quality biological data." The background is purple with a geometric pattern. Credit is given to Mark Van Oene, President and CEO of PacBio. The article is noted as a new article posted on October 6, 2026.
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PacBio @pacbio.bsky.social · 12/10/2026
All 11 contracted D4Z4 alleles detected with Kivvi using PacBio HiFi data. 🧬 A recent preprint shows how Kivvi characterizes repeat size, sequence, chromosome of origin & methylation in FSHD, with potential for broader genetic research. Read more: bit.ly/4yI2OGi
A graph displays a sequence alignment with five horizontal rows, each containing multiple short, color-coded segments. A key at the bottom indicates: yellow segments mean 'Reference', black for 'Variant', teal for 'Flank', and pink represents 'Low quality or missing or other base'. The rows are numbered from 1 to 10.
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PacBio @pacbio.bsky.social · 12/10/2026
PacBio is heading to Uppsala for #LRUA2026! 🇸🇪 As a Platinum Sponsor, we're excited to connect with researchers exploring long-read sequencing. Visit our booth to learn about Revio, Vega & SPRQ-Nx chemistry. Book a 1:1 meeting with our team: bit.ly/4yN4sGM
The image is a promotional graphic with a gradient background in pink and purple. It features text that states: "LRUA 2026. See you in Uppsala. Discover what’s next in HiFi sequencing. 2-4 November 2026." The name "PacBio" is prominently displayed at the bottom. White concentric lines are subtly visible across the background.
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PacBio @pacbio.bsky.social · 09/10/2026
A strong grant proposal starts with the right evidence. 📝 Answer a few quick questions about your research and funding goals to access personalized PacBio grant resources, including publications and benchmarking data. Build your case for funding: bit.ly/4h1ny3W
The image is a promotional graphic featuring text and a brochure. The top-left corner displays the PacBio and HiFi logos. Large bold text reads, "Get your research funded." A brochure titled "HiFi long-read sequencing" is pictured, labeled as a grant support resource. The background has abstract pastel shapes.
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PacBio @pacbio.bsky.social · 08/10/2026
5 publications. New discoveries powered by PacBio HiFi sequencing. 🧬 From a 12.1% diagnostic yield in unsolved rare disease cases to a single-cell atlas spanning 26 human tissues, explore the latest research using HiFi & Kinnex sequencing. Read more: bit.ly/4j86Z9m
Jul-Sep Pubs cover image featuring three circular photos: people sitting with a laptop, a screen with code, and a neon brain illustration.
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PacBio @pacbio.bsky.social · 08/10/2026
Microbial genomes are compact, but the questions are complex. PacBio HiFi sequencing helps resolve microbial genomes and characterize communities. Vega with SPRQ-Nx makes high-resolution sequencing more scalable. 📖 Download the HiFi Playbook: bit.ly/4zJLPV4
A promotional image for PacBio's SPRQ-Nx on the Vega System, highlighting HiFi microbial sequencing. Features include a pink Vega machine, a guide on getting started with microbial genomics, and icons for workflow examples and automation tips.
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PacBio @pacbio.bsky.social · 07/10/2026
Planning your time at #ASHG26? Add #PacBio booth #605 to your list! Meet our scientists, see Revio & Vega in action, and explore how HiFi sequencing is helping researchers see more of the genome. Explore our full program: bit.ly/3TDejiN
Pink banner for ASHG 2026 with the message, "Connect with us at Booth 605." It mentions the event dates, October 20-24, and hashtag #ASHG26. The bottom has the PacBio logo on a blue background.
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PacBio @pacbio.bsky.social · 07/10/2026
Four meaningful days at the 5th Undiagnosed Hackathon in Singapore! 🇸🇬 140 collaborators from 30+ countries came together to tackle challenging undiagnosed disease cases and help families searching for answers. PacBio was proud to contribute HiFi whole-genome & RNA sequencing support.
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PacBio @pacbio.bsky.social · 06/10/2026
Join us for the first Latin American Virtual Symposium on PacBio HiFi Sequencing! 🧬 Hear from experts about HiFi fundamentals, workflows, genomic applications, real-world use cases & get the chance to ask questions live. Register for free: bit.ly/4z3rGYG
Virtual symposium flyer for "First Latin American Symposium on PacBio HiFi Sequencing." Featured speakers include Wayra Navia, Jonas Korlach from PacBio, Alvaro Hernandez from the University of Illinois, Alexandre Aleixo from Instituto Tecnológico Vale, and Gerardo E. Fabian from UNAM. The event is on October 21 with listed start times in various time zones.
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PacBio @pacbio.bsky.social · 06/10/2026
We’re excited to announce a new collaboration with TychoBio to advance AI-driven RNA therapeutics for rare disease. #PacBio HiFi + Kinnex sequencing will generate full-length RNA data from 10,000+ samples to help train AI drug discovery models. Learn more about the collaboration: bit.ly/4AVHK0A
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PacBio @pacbio.bsky.social · 05/10/2026
Look beyond gene-level expression. New Kinnex prep kits are available now: run full-length RNA on 8-fold for the longest transcripts or 12-fold for throughput. Single-cell moves to 16-fold. Learn more: bit.ly/4APmLfM #PacBio #Kinnex #RNAseq
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PacBio @pacbio.bsky.social · 02/10/2026
#PacBio is headed to ASHG 2026 in Montréal! 🇨🇦 From complex variation to multiomic insights, see how HiFi sequencing is bringing more of the genome into view across human genomics. Discover what we have planned for #ASHG26: bit.ly/3TDejiN
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PacBio @pacbio.bsky.social · 01/10/2026
Congratulations to Sampled on its new five-year VA contract supporting the Million Veteran Program! 👏 With multiple PacBio Revio systems, Sampled is bringing scalable HiFi sequencing to one of the world’s largest research programs of its kind. Read more: prn.to/4y5klHq
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PacBio @pacbio.bsky.social · 30/09/2026
HiFi sequencing is now more accessible for biopharma research. See how Vega SPRQ-Nx supports lower DNA input, more data per run, faster run times, and regulated workflows across therapeutic development applications. 📖 Download the HiFi Playbook: bit.ly/3UiQDjV
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PacBio @pacbio.bsky.social · 28/09/2026
Hammond et al. found HiFi WGS F1 scores for SNVs & indels exceeded 99% at ~15x & ~25x coverage. 📊 Strong data can strengthen the scientific case for your grant. Learn how to select the right evidence + access PacBio grant resources & free 1:1 support: bit.ly/4hk5LGI
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PacBio @pacbio.bsky.social · 25/09/2026
Microbial studies need more than answers. They need scale. 🧬 One Vega SPRQ-Nx run can support up to 384 microbial de novo assembly samples, 96 shotgun metagenomic profiling communities, or 1,536 Kinnex 16S rRNA communities. 📖 Download the playbook: bit.ly/4zJLPV4
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PacBio @pacbio.bsky.social · 23/09/2026
Benchmarking by Harvey et al. shows PacBio HiFi achieves higher indel & SV recall at 20x than ONT achieves at 60x+. 📊 Citing the right peer-reviewed data is key to a winning grant proposal. See how our literature library helps you write yours faster: bit.ly/4ycWZ3q
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PacBio @pacbio.bsky.social · 22/09/2026
September is NICU Awareness Month. 💙 When every hour matters in time-critical cases, rapid PacBio HiFi whole-genome sequencing delivers a complete view of the genome to help researchers investigate complex genetic changes. 📖 Access the resource bundle: bit.ly/4eYvYIp
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PacBio @pacbio.bsky.social · 22/09/2026
We’re excited to announce 4 winners for the 2026 Metagenomics SMRT Grant! 🧬 From infant resistomes and hereditary cancer to soil pathogens and HPV persistence, see how these researchers are driving discovery with PacBio HiFi sequencing. Meet the awardees: bit.ly/4rotusF
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PacBio @pacbio.bsky.social · 18/09/2026
Could long-read sequencing improve your targeted workflow? Explore how PacBio HiFi sequencing supports repeat expansion, HLA typing, and PGx, while Vega SPRQ-Nx chemistry delivers lower DNA input and faster runs. 📖 Read the playbook: bit.ly/4wTy43t
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PacBio @pacbio.bsky.social · 17/09/2026
Writing a grant? Let us help build your case for funding. 🧬 Answer a few quick questions about your project and grant stage to get tailored feasibility data, budget guidance, and evidence for HiFi sequencing. Get started: bit.ly/4h1ny3W
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PacBio @pacbio.bsky.social · 17/09/2026
This #InternationalMicroorganismDay, we celebrate the tiny organisms with an enormous impact on health, ecosystems, food, and science. PacBio highly accurate long-read sequencing helps researchers reveal microbial diversity in greater detail. Tech note: bit.ly/4yGM5Cz
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PacBio @pacbio.bsky.social · 16/09/2026
Catch our expert session on new SPRQ-Nx chemistry for the Vega system! 🧬 See what changes for your workflow: • Up to 90 Gb/run • 500 ng input for limited samples • Faster turnaround times • 21 CFR Part 11 support for GMP labs Access the Q&A: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 15/09/2026
At the Nordic Conference on Future Health (NCFH) today? Join our workshop at 15:30 to explore what’s next in HiFi sequencing! Discover updates on Revio and Vega, and see how HiFi is advancing population genetics. 🧬 Connect with the PacBio team on-site: bit.ly/3Sq8KUt
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PacBio @pacbio.bsky.social · 14/09/2026
⏰ Last chance to register! Join our expert panel discussion to learn why long-read sequencing has become an essential foundation for modern multiomics & how it accelerates precision medicine. Save your spot: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing #Webinar
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PacBio @pacbio.bsky.social · 10/09/2026
Explore our Vega expert session to see how SPRQ-Nx chemistry delivers 50% more HiFi data (up to 90 Gb/run), ~40% lower cost per Gb, & 500 ng DNA input for limited samples. 🚀 See how 21 CFR Part 11 support enables regulated workflows. Get access here: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 09/09/2026
Heading to #NCFH2026? 🧬 Join our workshop to explore what’s next in HiFi sequencing with Revio, featuring Prof. Lili Milani & Riki Aydeniz. Learn about population-scale genomics & SPRQ-Nx. Meet us on-site: bit.ly/3Sq8KUt #PacBio
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PacBio @pacbio.bsky.social · 08/09/2026
PacBio CEO Mark Van Oene explains why accurate, high-quality long-read data is foundationally important for AI-driven therapeutic research. Watch the clip, then hear the full conversation on @mendelspod: bit.ly/468AYq3
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PacBio @pacbio.bsky.social · 08/09/2026
Heading to NCFH 2026 next week? Join our corporate workshop to discover what’s next in HiFi sequencing with Revio and Vega, explore product updates, and see how HiFi powers population genetics! 🧬 Book a meeting to connect with the PacBio team at NCFH: bit.ly/3Sq8KUt
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PacBio @pacbio.bsky.social · 07/09/2026
Fewer samples. More data. Faster answers. 🧬 That's what's new with Vega SPRQ-Nx chemistry. Our HiFi Playbook for Biopharma explores how lower DNA input, shorter run times, & 21 CFR Part 11 support help streamline therapeutic research. 📖 Download here: bit.ly/3UiQDjV
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PacBio @pacbio.bsky.social · 04/09/2026
SPRQ-Nx chemistry for the Vega system is here! 🧬 Supercharge your benchtop HiFi sequencing with up to 90 Gb of data per run, lower DNA input requirements, full methylation calling, & 21 CFR Part 11 support. Read the blog to see what’s new: bit.ly/3Uizffa
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PacBio @pacbio.bsky.social · 03/09/2026
PacBio CEO Mark Van Oene joined @mendelspod this week to talk newborn screening, genomic information from birth, and where long-read sequencing could take us next. Catch the full episode here: bit.ly/4yoMkSZ
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PacBio @pacbio.bsky.social · 03/09/2026
Bring high-quality long-read microbial genomics closer to the bench! 🧬 With Vega & SPRQ-Nx chemistry, access HiFi sequencing for isolate assembly, metagenomic profiling, & full-length 16S studies. 📖 Download the HiFi Playbook for Microbiology: bit.ly/4zJLPV4
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PacBio @pacbio.bsky.social · 02/09/2026
Step into a new era of long-read multiomics! 🧬 Join leading experts as they share how long-read sequencing advances rare disease diagnostics, uncovers neurodegenerative mechanisms, & supports AI-driven therapeutic discovery. Register: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing
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PacBio @pacbio.bsky.social · 01/09/2026
Watch our expert session on Vega benchtop long-read sequencing with SPRQ-Nx chemistry! 🧬 • 50% more HiFi data (up to 90 Gb/run) • ~40% lower cost per Gb • 500 ng DNA input Access the full presentation and Q&A: bit.ly/3Uobfar
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PacBio @pacbio.bsky.social · 31/08/2026
Find your ideal sequencing match: bit.ly/3QUZRl5 🧬 Answer 3 quick questions in under a minute to get matched with a personalized HiFi Fit Kit tailored to your specific research goals. Get instant access to your customized resource bundle!
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PacBio @pacbio.bsky.social · 27/08/2026
Difficult genomic regions? Limited DNA samples? 🧬 The HiFi Playbook for Clinical Targeted Sequencing explores how Vega SPRQ-Nx chemistry delivers highly accurate long-read data with lower DNA input & shorter run times. 📖 Download the playbook: bit.ly/4wTy43t #TargetedSequencing
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PacBio @pacbio.bsky.social · 26/08/2026
Accelerate time-critical genomic research with rapid HiFi WGS! 🧬 Our end-to-end workflow delivers genome-wide variant calls in under 30 hours, capturing structural variants, repeat expansions, & phased haplotypes. Access your complimentary resource bundle: bit.ly/4eYvYIp
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PacBio @pacbio.bsky.social · 25/08/2026
Join our webinar to explore how long-read multiomics is redefining human disease research! 🧬 Learn how leading scientists integrate genomic, epigenomic, & proteomic data to advance rare disease, neurodegeneration, & AI drug discovery. Register: bit.ly/4h4MGJ4 #PacBio #Multiomics #HiFiSequencing
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PacBio @pacbio.bsky.social · 24/08/2026
From targeted amplicons in 2013 to 2,000+ human genomes today! 🧬 See how Dr. Adam Ameur, Uppsala University, & SciLifeLab are scaling the Genome of Sweden project using PacBio Revio & SPRQ-Nx chemistry to lower population genomics costs. Read the story: bit.ly/4gO6Fea #PacBio #Revio #SPRQNx
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PacBio @pacbio.bsky.social · 21/08/2026
Featured in The Scientist: Dr. Alexander Hoischen discusses how long-read sequencing on the Revio system is helping end the rare disease diagnostic odyssey by filling the gaps left by short reads. Read the interview: bit.ly/4i3LKFl #PacBio #Revio #RareDisease #HiFiSequencing
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PacBio @pacbio.bsky.social · 20/08/2026
Last call! Don't forget to register for our upcoming expert panel on PacBio HiFi sequencing in biopharma and biotech R&D. Learn how industry leaders apply long-read sequencing to drug discovery, gene editing, and mRNA therapeutics. Register now: bit.ly/4g3QSX4 #PacBio #Biopharma #DrugDiscovery
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PacBio @pacbio.bsky.social · 19/08/2026
Ready to optimize your next sequencing project? Skip the manual searching and let our quick quiz find your tailored setup in under a minute. Answer 3 fast questions to unlock your custom HiFi resource kit: bit.ly/3QUZRl5 #PacBio #HiFiSequencing #Genomics
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PacBio @pacbio.bsky.social · 18/08/2026
Leveling the playing field, one long read at a time. Vega SPRQ-Nx chemistry is now shipping! Bring higher throughput, lower DNA input, shorter run times, and expanded methylation detection to your benchtop. What will you discover? Learn more: bit.ly/3TCbMoR
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