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Organic & Biomolecular Chemistry

@orgbiomolchem.rsc.org
590 followers 222 following 556 posts

Rapid publication of organic synthesis, physical organic, chemical biology and supramolecular chemistry research. Published by @rsc.org 🌐 Website: rsc.li/orgbiomolchem

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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 22h
Take a look in our latest issue at research from Haibin Yu, Bin Yu, Er-Qing Li & co. on the solvent-controlled divergent (4+1) cycloaddition of 1,4-enynoates with amines #orgchem 📍Zhengzhou University doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 16/10/2026
Be sure to read this review from Pintu Kumar Mandal et al. at CSIR-CDRI in our latest issue looking at the recent advances in the thioglycosylation of indoles and tryptophan and their application in total synthesis #orgchem #natprod Find it in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 15/10/2026
Don't miss this paper in our latest issue by Thi Khanh Huyen Nghe & Hee-Kwon Kim from Jeonbuk National University describing photocatalyst-free, visible-light-induced borylation and selenylation of aryltriazenes #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 14/10/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess research from Klaus Schaper & co. @hhu.de reporting highly reducing tri-substituted phenothiazines as novel photoredox catalysts #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 13/10/2026
🔓Be sure to read #OpenAccess research from Siegfried R. Waldvogel et al. at the Max Planck Institute for Chemical Energy Conversion in our latest issue on Witkop–Winterfeldt oxidation using electrochemically generated para-periodate #orgchem Find their full report below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 12/10/2026
🔓Don't miss in our latest issue this #OpenAccess paper by Evelien Renders, Alexander X. Jones & co. from Johnson & Johnson reporting nickel electrocatalytic C(sp3)–C(sp3) cross-coupling from activated carboxylic acids and amines #orgchem Check it out in full here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 11/10/2026
Check out this review by Chithra Mohan & co. from Mahatma Gandhi University in our latest issue discussing visible-light-driven alkynylation as a sustainable approach to rigid molecular architectures #orgchem Read the full article on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 10/10/2026
🔓Take a look in our latest issue at #OpenAccess research from Eric Deniau, Lydie Pélinski, Till Bousquet et al. describing a visible-light-driven carbamoyl radical addition to 3-methylene isoindolinones #orgchem 📍 @univlille.bsky.social doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 09/10/2026
Be sure to read this paper by Wei Tan, Feng Shi & co. from Jiangsu Normal University in our latest issue reporting the Brønsted acid-catalyzed (3+2) cycloaddition of 2-indolylmethanols with o-alkynylnaphthols #orgchem Find it in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 08/10/2026
🔓Don't miss this #OpenAccess paper in our latest issue from Alexei V. Demchenko et al. @slu-official.bsky.social overcoming reactivity limitations in glycosylation with a novel protecting group #orgchem Check it out in full on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 07/10/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess research behind the cover by Naoya Kumagai & co. from Keio University describing how intramolecular hydrogen bonding topology modulates fluorescence in C4N4 fluorophores #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 06/10/2026
🔓Be sure to read #OpenAccess research from Michael T. Taylor & co. @uarizona.bsky.social in our latest issue on a simple synthesis and functionalization of α-hydroxyglycine-containing peptide fragments #orgchem Find their full report on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 05/10/2026
🔓Don't miss this #OpenAccess paper in our latest issue by Martin D. Witte, Adriaan J. Minnaard et al. @rug.nl reporting the electrochemical oxidative amidation of alcohols towards N-acyl azoles as precursors for amides, esters and thioesters #orgchem Check it out here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 04/10/2026
Check out this paper from Seema Dhiman, Mahipal Yadav & co. at the University of Delhi in our latest issue describing sonochemical N-nitrosation of secondary amines under mild conditions #orgchem Read it in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 03/10/2026
Take a look in our latest issue at research from Quan-Quan Zhou, Jie-Ping Wan et al. reporting the transition metal-free photocatalytic α-C–H trifluoromethylation of enaminones #orgchem 📍Jiangxi Normal University doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 02/10/2026
🔓Be sure to read this #OpenAccess paper by Zihuan Fu & Heather D. Maynard @uclacb.bsky.social in our latest issue describing how alternating iterative exponential growth oligomers serve as a platform for hydrophilic antibody–drug conjugates #medchem #orgchem Find it in full👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 01/10/2026
Don't miss a paper from Takeharu Haino, Nozomu Suzuki et al. at Kobe University in our latest issue describing rapid single-spectrum NMR estimation of multiple binding constants in diastereomer-resolved host–guest systems #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 30/09/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess paper behind the cover by Artur Kasprzak & co. from Warsaw University of Technology & Medical University of Warsaw obtaining covalent and non-covalent conjugates of bowl-shaped sumanene and 5-fluorouracil #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 29/09/2026
🔓Be sure to read in our latest issue #OpenAccess research from Joseph B. Sweeney & Julien Doulcet @lancasteruni.bsky.social using an aryne–arylamine–aldehyde three-component reaction for the synthesis of drug-like 2-aminobenzyl ethers #orgchem #medchem Find in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 28/09/2026
Don't miss this review in our latest issue from @kanvah.bsky.social et al. at IIT Gandhinagar highlighting the evolution of chemical biology approaches for detecting and profiling protein citrullination #orgchem #chembio Check it out on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 27/09/2026
🔓Check out a #OpenAccess paper by Alison Thompson & co. @dalhousie.bsky.social in our latest issue developing a new nitrosylation reaction for pyrroles, featuring tert-butyl nitrite as a mild nitrosylation agent #orgchem Read the full article here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 26/09/2026
Take a look in our latest issue at a paper by Xiaoqiang Yu et al. using 9-fluorenone as a photosensitizer for nickel-catalyzed reductive cross-coupling of aryl halides with alkyl iodides #orgchem 📍Dalian University of Technology doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 25/09/2026
🔓Be sure to read #OpenAccess research from Haruki Mizoguchi, Akira Sakakura & co. at Okayama University in our latest issue reporting the stereoselective synthesis of β,β-diborylalanine and its incorporation into oligopeptides #orgchem Find it in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 24/09/2026
🔓Don't miss this #OpenAccess paper in our latest issue by Stéphane Le Calvé, Mourad Elhabiri et al. @unistra.fr describing the hemisynthesis of ribazole-2′,3′-cyclophosphate #natprod #orgchem Check it out in full on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 23/09/2026
📢Our latest issue is online! Check out the cover article by Nasir Rasool, @sumbal6s.bsky.social, @jamal7r.bsky.social & co. at Government College University Faisalabad & @labso.bsky.social reviewing recent advances in titanium-mediated organic transformations #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 22/09/2026
Read a paper by Srihari Pabbaraja, Goverdhan Mehta et al. at CSIR-IICT & University of Hyderabad in our latest issue describing a transition-metal-free cascade approach to indoloindolizines for the synthesis of bioactive homofascaplysin C analogues #orgchem Find it below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 21/09/2026
🔓Don't miss this #OpenAccess review in our latest issue from Herman O. Sintim & co. @notredame.bsky.social revisiting multicomponent Doebner and Povarov quinoline synthesis for modern-day drug-discovery #orgchem #medchem Check out the full article here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 20/09/2026
Check out this paper by Yulai Hu et al. from Northwest Normal University in our latest issue on visible-light-induced radical fluoroalkylation/cyclization for the synthesis of 2-fluoroalkyl-3-aminoindoles via an EDA complex #orgchem Read it in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 19/09/2026
Take a look in our latest issue at research from Badrodin Ayyub Shaikh reporting a SmI2-mediated tandem cyclization route for stereoselective synthesis of the tetracyclic core of daphenylline #orgchem 📍IISc Bangalore doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 18/09/2026
🔓Be sure to read this #OpenAccess paper from Pavel Lhoták & co. at UCT Prague in our latest issue studying the conformational preferences and dynamic behavior of 2-monothiacalix[4]arene #orgchem Find the full report on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 17/09/2026
Don't miss this paper in our latest issue from Wenling Qin, Zhen Wang et al. at Chongqing University describing the asymmetric synthesis of fused seven-membered chromanones from 3-hydroxy chromones and vinyl ethylene carbonates #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 16/09/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess review behind the cover by Harshita Kumari & co. from the University of Cincinnati discussing macrocycle-mediated modulation and repurposing of antibacterial and non-antibacterial drugs #orgchem #medchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 15/09/2026
🔓Take a look at a #OpenAccess paper from Francesca Cardano, Marco Blangetti, Andrea Fin & co. in our latest issue on the structural and photophysical evaluation of O-alkoxy-substituted BODIPY dyes in liposomes #orgchem 📍Universita di Torino doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 14/09/2026
Don't miss in our latest issue this review by Zhong-Wei Hou, Lei Wang et al. from Taizhou University summarising the latest advancements in utilizing 9,10-phenanthrenequinone as a versatile catalyst for organic reactions #orgchem Check out their full article here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 11/09/2026
🔓Be sure to read this #OpenAccess paper from @emmertlab.bsky.social, Ozgur Yilmaz & co. at Mersin University & Merck & Co. in our latest issue describing a general, operationally simple N-dealkylation of simple and complex tertiary amines #orgchem Find it here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 10/09/2026
Don't miss this review in our latest issue covering the recent trends in synthetic approaches to α-amino ketones by Mariusz Zalewski & Sebastian Stecko from the Institute of Organic Chemistry, Polish Academy of Sciences #orgchem Check it out in full below👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 09/09/2026
Check out this paper from Samik Nanda et al. at IIT Kharagpur in our latest issue describing a chemoenzymatic approach to towards naturally occurring macrolactams melearorides A and B #orgchem #natprod Read their full report on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 08/09/2026
🔓Take a look in our latest issue at this #OpenAccess paper from Jolene P. Reid, Michael O. Wolf & co. investigating the photophysics of click-functionalized 2,2′-bithienyl flexible Lewis pairs #orgchem #compchem 📍 @science.ubc.ca doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 07/09/2026
🔓Be sure to read this #OpenAccess paper by Omar Boutureira, Yolanda Díaz, M. Isabel Matheu et al. from @urv.cat in our latest issue describing stereoselective access to allenic sphingosine analogues as SphK inhibitors #orgchem #medchem Find it in full on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 04/09/2026
Don't miss this review in our latest issue by Prodeep Phukan et al. from Gauhati University looking at the recent advances in sulfonyl guanidine synthesis #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 03/09/2026
📢Our latest issue is now online! 🔓Check out the #OpenAccess paper behind the cover from @knipechem.bsky.social, Sam Thompson & co. @unisouthampton.bsky.social & @ox.ac.uk reporting water-soluble β-strand peptidomimetics #orgchem doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 01/09/2026
🔓Be sure to read in our latest issue #OpenAccess research from Thomas Wirth & co. @cardiffuni.bsky.social describing the continuous flow electrochemical oxidation of activated methylarenes using O2 #orgchem Find their full report on our website🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 31/08/2026
Don't miss a paper, part of our collection celebrating the 65th birthdays of Jay Siegel & Kim Baldridge, by Ho Yu Au-Yeung et al. at the University of Hong Kong investigating the interplay of ring size, rigidity & curvature in catenane complexes #orgchem Check it out here👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 30/08/2026
Check out this review from Ahmed Khalil at King Faisal University in our latest issue summarising synthetic strategies, photophysical properties and biomedical applications of phthalocyanine conjugated nucleosides #orgchem Read it in full below🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 29/08/2026
Take a look at research in our latest issue from Santosh B. Mhaske & co. reporting the organocatalytic stereoselective synthesis of amino acid-fused quinazolinone based triazacyclic frameworks #orgchem 📍CSIR-NCL doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 28/08/2026
Be sure to read a paper by Rodrigo O. M. A. de Souza, Rodolfo G. Fiorot et al. from Universidade Federal Fluminense in our latest issue describing the regioselective acid-catalyzed conversion of cannabidiol into THC isomers #orgchem Find the full article on our website👇 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 27/08/2026
🔓Don't miss this #OpenAccess paper in our latest issue from @myanificent.bsky.social, @drmichaeljhallchem.bsky.social & co. @newcastleuni.bsky.social describing improved aromatic Finkelstein reactions for the synthesis of iodinated BODIPYs #orgchem Check it out in full here🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 26/08/2026
📢Our latest issue is online! The cover is from the Editorial of our joint themed collection with @orgchemfront.rsc.org celebrating the 65th birthdays of Jay Siegel & Kim Baldridge, guest edited by @jessenlab.bsky.social, Mihaiela Stuparu & @chemguyeli.bsky.social #chemsky doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 25/08/2026
Read this paper from Liangyong Mei & co. at the University of North Florida in our latest issue describing the synthesis of CF3-containing dihydropyrido[1,2-a]indolones via a visible-light-promoted radical cascade [4+2]/[4+2] cycloaddition #orgchem Find it in full🔽 doi.org/10.1039/d6ob...
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Organic & Biomolecular Chemistry @orgbiomolchem.rsc.org · 24/08/2026
🔓Don't miss #OpenAccess research in our latest issue from Lukas J. Gooßen et al. @ruhr-uni-bochum.de reporting a trifluoroacetate-derived reagent for trifluoromethylation of (hetero)arenes #orgchem Check it out in full here👇 doi.org/10.1039/d6ob...
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