The number of corneal transplants and procurements continues to increase worldwide, though not always relative to population rises, and long-term systemic medication use in older women may increase the risk of AMD.

ANAHEIM, Calif. — Even though studies have linked GLP-1s to development of nonarteritic anterior ischemic neuropathy, the risk is not great enough to warrant stopping the medication, according to a speaker at Academy 2026. “We need to follow the data, not so much what is being reported in the media,” Leonard V. Messner, OD, FAAO, professor of optometry at Illinois College of Optometry, said. “The best approach is vigilance, not a knee-jerk response.” He emphasized that “the overall absolute risk remains very, very low.” In the U.S., lawsuits are underway against GLP-1 manufacturers Novo Nordisk

Welcome to another edition of CEDARS/ASPENS Debates. CEDARS/ASPENS is a society of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology. This month we are discussing the management of severe neurotrophic keratitis (NK), an uncommon but severe degenerative disease of the cornea characterized by compromised corneal sensory innervation. Oxervate (cenegermin-bkbj, Dompé), a recombinant human nerve growth factor for topical administration, has been a game changer in the treatment of patients with NK. It is FDA approved but requires a

Welcome to another edition of CEDARS/ASPENS Debates. CEDARS/ASPENS is a society of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology. This month we are discussing the management of severe neurotrophic keratitis (NK), an uncommon but severe degenerative disease of the cornea characterized by compromised corneal sensory innervation. Oxervate (cenegermin-bkbj, Dompé), a recombinant human nerve growth factor for topical administration, has been a game changer in the treatment of patients with NK. It is FDA approved but requires a

ANAHEIM, Calif. — Treating dry eye disease with both Xiidra and Miebo led to significant improvements in signs and symptoms, with most patients still using both drops months later, according to data presented at Academy 2026. The finding comes shortly after Bausch + Lomb announced that an eye drop combining Xiidra (lifitegrast ophthalmic solution 5%) and Miebo (perfluorohexyloctane ophthalmic solution) would be evaluated in a phase 3 study. “As a clinician treating many patients with moderate to severe dry eye disease, I regularly incorporate pharmaceutical treatments with different mechanisms

Researchers developed and validated a new classification system that may standardize reporting of all relevant grades of clinical presentation and management of surgical site outcomes, according to published results. To develop a classification system for dehiscence, inflammation/infection, seroma and hematoma (DISH) that would apply across multiple medical specialties, Giles Bond-Smith, MBBS, BSc, FRCS, a consultant liver, pancreatic and biliary, abdominal wall reconstruction and emergency surgeon at Oxford University Hospitals NHS Foundation Trust, and colleagues performed a systematic

SpyGlass Pharma announced the acquisition of Advanced Vision Science in an effort to boost its IOL manufacturing capacity, according to a press release. SpyGlass acquired all outstanding stock of Advanced Vision Science (AVS) for $13 million in cash. AVS was a subsidiary of Santen Pharmaceutical and is the current supplier of IOLs for Spyglass at it develops the bimatoprost drug pad-IOL, or BIM-IOL, system, which is under investigation in two phase 3 trials, according to the release. As part of the deal, AVS will continue to supply Santen with some types of IOLs for commercialization in Japan

SpyGlass Pharma announced the acquisition of Advanced Vision Science in an effort to boost its IOL manufacturing capacity, according to a press release. SpyGlass acquired all outstanding stock of Advanced Vision Science (AVS) for $13 million in cash. AVS was a subsidiary of Santen Pharmaceutical and is the current supplier of IOLs for Spyglass at it develops the bimatoprost drug pad-IOL, or BIM-IOL, system, which is under investigation in two phase 3 trials, according to the release. As part of the deal, AVS will continue to supply Santen with some types of IOLs for commercialization in Japan

Eye, Published online: 02 October 2026; doi:10.1038/s41433-026-04961-9Thirty-year silicone implant granuloma

Eye, Published online: 02 October 2026; doi:10.1038/s41433-026-04963-7Type 4 macular neovascularisation arising from a congenital toxoplasmosis scar

Publication date: Available online 2 October 2026 Source: Experimental Eye Research Author(s): Rui Dou, Changlong Wu, Yuyan Liu, Guoge Han, Yong Tang, Xue Bi, Wei Zhang, Chao Xue, Quanhong Han, Yanhua Chu

Volume 34, Issue 7, September 2026, Page 1387-1389 .

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Depressive symptoms were common and closely associated with lower modified CarCGQoL scores

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04875-6Choroidal tuberculoma as an initial presenting sign of miliary tuberculosis

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04944-wRetinal capillary haemangioblastoma with localised serous retinal detachment

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04845-y‘A torpedo in the storm—multimodal imaging of rod cone dystrophy coexisting with torpedo maculopathy’

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04908-0Enhanced keratometry for IOL power calculation after myopic LASIK: a multi-device comparison

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04938-8Multidrug antifungal resistance and clinical outcomes in fungal keratitis: a prospective study in a South Indian population

Eye, Published online: 01 October 2026; doi:10.1038/s41433-026-04534-wEfficacy and safety of 0.01% atropine in Chinese children with nearwork-induced transient myopia: a randomised, double-blind, placebo-controlled trial

ANAHEIM, Calif. — Patients with dry eye disease who used Tryptyr reported significantly improved quality of life in addition to reduced dry eye symptoms, according to data presented at Academy 2026. Tryptyr (acoltremon ophthalmic solution 0.003%, Alcon), approved by the FDA in 2025, is an eye drop designed to treat dry eye disease by stimulating natural tear production. “Now that the drug is on the market, we wanted to see how it actually performed in the real world,” Andrew D. Pucker, OD, PhD, FAAO, of Eminent Ophthalmic Services in Georgia, told Healio. “What did patients experience after

ANAHEIM, Calif. — Fitting patients with contact lenses may be more profitable to an optometric practice than prescribing spectacles alone, according to a report from the Contact Lens Institute. The institute released the full results of this study at Academy 2026. “A lot of practitioners worry about whether it’s worth fitting contact lenses. I think these data prove that it is,” Lyndon Jones, BSc, PhD, DSc, FCAHS, FCOptom, DipCLP, DipOrth, FAAO, FIACLE, FBCLA, director of the Centre for Ocular Research & Education at the University of Waterloo, told Healio. {{VIDEO}} Independent eye care and

ANAHEIM, Calif. — Prostaglandin analogs for the treatment of glaucoma may have effects on the cornea that lead to lower IOP measurements, potentially impacting management of the disease, according to data presented at Academy 2026. “For a long time, we have known that the biomechanics of the cornea — how it responds to forces — can affect the accuracy of intraocular pressure measurements,” study author Daniel Epshtein, OD, FAAO, associate clinical professor at SUNY College of Optometry, told Healio. “Though rarely considered in day-to-day clinic, research has also shown that chronic

Growing up, Naomi Lawrence-Reid, MD, always knew she wanted to be a doctor. Her career as a physician looks different from what she pictured as a medical student, but she said she wouldn’t have it any other way. After medical school, Lawrence-Reid completed a pediatrics residency and then began working in a pediatric emergency medicine department. “I got excellent experience,” Lawrence-Reid told Healio. “You learn to work fast, to work hard, to make decisions quickly about whether a child is sick or not or needs a procedure or intervention. But after about 3 years, I knew that was not my forever

Growing up, Naomi Lawrence-Reid, MD, always knew she wanted to be a doctor. Her career as a physician looks different from what she pictured as a medical student, but she said she wouldn’t have it any other way. After medical school, Lawrence-Reid completed a pediatrics residency and then began working in a pediatric emergency medicine department. “I got excellent experience,” Lawrence-Reid told Healio. “You learn to work fast, to work hard, to make decisions quickly about whether a child is sick or not or needs a procedure or intervention. But after about 3 years, I knew that was not my forever

ANAHEIM, Calif. — Quality of vision and subjective experience in children wearing SightGlass Vision Diffusion Optics Technology were similar to single vision spectacle lens wear, according to two studies presented at Academy 2026. “Practitioners can be confident that they can prescribe [DOT] lenses in a similar way to standard single vision lenses,” David Webley, MCOptom, FBCLA, senior director for clinical, medical and professional affairs at SightGlass Vision, told Healio. “The experience of their patients is going to be as good with the DOT lenses,” which use contrast modulation to control

The management of keratoconus has evolved substantially over 3 decades. While corneal transplantation was historically the only surgical option for advanced disease, intracorneal ring segments (ICRS), first implanted by Walton Nosé in 1993 and later popularized by Joseph Colin, offered a less invasive way to improve corneal symmetry and reduce irregular astigmatism. Conventional ICRS are made of synthetic PMMA, and despite their efficacy, they carry substantial risks, including extrusion, corneal melt, neovascularization and stress-induced stromal necrosis, particularly when placed

The management of keratoconus has evolved substantially over 3 decades. While corneal transplantation was historically the only surgical option for advanced disease, intracorneal ring segments (ICRS), first implanted by Walton Nosé in 1993 and later popularized by Joseph Colin, offered a less invasive way to improve corneal symmetry and reduce irregular astigmatism. Conventional ICRS are made of synthetic PMMA, and despite their efficacy, they carry substantial risks, including extrusion, corneal melt, neovascularization and stress-induced stromal necrosis, particularly when placed

HHS launched a multi-component effort intended to improve the speed and efficiency with which clinical trials are conducted. The series of initiatives is designed to eliminate duplication, ensure more efficient enrollment and provide patients with earlier access to promising therapies. “The goal is straightforward — generate rigorous evidence faster, reduce unnecessary costs and burdens, and make the United States the best place in the world to engage in clinical trial research,” HHS Secretary Robert F. Kennedy Jr. said during a launch event held at UT Dell Medical Center in

HHS launched a multi-component effort intended to improve the speed and efficiency with which clinical trials are conducted. The series of initiatives is designed to eliminate duplication, ensure more efficient enrollment and provide patients with earlier access to promising therapies. “The goal is straightforward — generate rigorous evidence faster, reduce unnecessary costs and burdens, and make the United States the best place in the world to engage in clinical trial research,” HHS Secretary Robert F. Kennedy Jr. said during a launch event held at UT Dell Medical Center in

This position statement is intended to educate and guide accrediting organizations, manufacturers, and other policymakers regarding high level disinfection of certain ophthalmic devices in light of available evidence. It is not intended to supersede applicable law or regulations, nor to prescribe physicians’ procurement choices.

Younger patients with primary acquired nasolacrimal duct obstruction (PANDO) who undergo dacryocystorhinostomy do not appear to have an increased risk of clinically occult pathology.

In part one of the SPECTRA clinical trial, 4D-150, an intravitreal gene therapy, demonstrated positive safety outcomes as well as vision gains and central subfield thickness reduction in patients with diabetic macular edema. “For DME patients, the current treatment paradigm requires time-consuming retinal clinic visits and anti-VEGF injections every 4 to 8 weeks,” Arshad Khanani, MD, MA, FASRS, chair of 4D Molecular Therapeutics’ retina advisory board, told Healio. “This is on top of other regular physician visits needed to control their diabetes. Because of this rigorous schedule, many

In part one of the SPECTRA clinical trial, 4D-150, an intravitreal gene therapy, demonstrated positive safety outcomes as well as vision gains and central subfield thickness reduction in patients with diabetic macular edema. “For DME patients, the current treatment paradigm requires time-consuming retinal clinic visits and anti-VEGF injections every 4 to 8 weeks,” Arshad Khanani, MD, MA, FASRS, chair of 4D Molecular Therapeutics’ retina advisory board, told Healio. “This is on top of other regular physician visits needed to control their diabetes. Because of this rigorous schedule, many

We thank Liu and Peng for their thoughtful comments on our study and welcome the opportunity to clarify our findings.

To characterize the phenotypic spectrum of mid-phase hyperfluorescent plaques (MPHPs) on indocyanine green angiography (ICGA) in eyes with central serous chorioretinopathy (CSCR) and to evaluate their relationship with corresponding optical coherence tomography (OCT) features.

CHICAGO — SMART goals — an approach centered on making objectives specific, measurable, achievable, relevant and time-bound — provide a useful framework for personal growth, a speaker at the Women in Medicine Summit said. However, before setting a SMART goal, physicians should first assess their readiness, confidence and the importance of the goal to improve their chances of success, according to Robyn Tiger, MD, DipABLM, FACLM, founder of StressFreeMD. “It’s wonderful that we have this model of SMART goals, but when I was coaching other physicians on those, there were lots of times they

CHICAGO — SMART goals — an approach centered on making objectives specific, measurable, achievable, relevant and time-bound — provide a useful framework for personal growth, a speaker at the Women in Medicine Summit said. However, before setting a SMART goal, physicians should first assess their readiness, confidence and the importance of the goal to improve their chances of success, according to Robyn Tiger, MD, DipABLM, FACLM, founder of StressFreeMD. “It’s wonderful that we have this model of SMART goals, but when I was coaching other physicians on those, there were lots of times they

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Letter for the article Efficacy of Punctal Occlusion Techniques in Tear Drainage Disorders: A Systematic Review and Meta-Analysis

Nd:YAG capsulotomies rates varied accordingly to the FineVision IOL model. Differences in IOL material (hydrophilic or hydrophobic) and haptic design.

The authors regret two typographical errors in the abstract and manuscript that resulted in inconsistencies with their corresponding figures. First, the hazard ratio for the 1-year diabetic retinopathy (DR) progression analysis was reported as 0.69 in the abstract and manuscript Results section. The correct hazard ratio is 0.79, consistent with the database and published Figure 2. Second, for our DR complications analysis, the abstract and Results section incorrectly report the 6-month to 3-year timeframe as statistically significant.

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The FDA has issued a final rule that would remove references to animal studies in its drug safety regulations, as part of a larger effort across HHS to reduce what it calls “unnecessary animal testing” in biomedical research. In addition to the new FDA rule, which would take effect Feb. 4, 2027, the NIH simultaneously announced a series of new initiatives intended to develop and promote alternatives to animal testing, including more than $88 million in funding for biomedical infrastructure projects nationwide. “We are moving HHS toward a new era of biomedical research that

The FDA has issued a final rule that would remove references to animal studies in its drug safety regulations, as part of a larger effort across HHS to reduce what it calls “unnecessary animal testing” in biomedical research. In addition to the new FDA rule, which would take effect Feb. 4, 2027, the NIH simultaneously announced a series of new initiatives intended to develop and promote alternatives to animal testing, including more than $88 million in funding for biomedical infrastructure projects nationwide. “We are moving HHS toward a new era of biomedical research that

Publication date: Available online 30 September 2026 Source: Progress in Retinal and Eye Research Author(s): Huixin Tang, Freekje van Asten, Yu Yu, Liu Lyu, Tos TJM Berendschot

To evaluate peripheral vascular and retinal findings in school-aged children with spontaneously regressed zone II, stage 2 retinopathy of prematurity (ROP) without plus disease, and to investigate risk factors for persistent avascular retina (PAR).

Melanomas of the iris, choroid and ciliary body are known collectively as uveal melanomas (UM). The age adjusted risk ranges from 5 per million in the US to 8 per 1 million in northern European countries, making it the most common intraocular tumor in adults.1,2 Unfortunately, the risk for metastatic development reaches 50% with minimal chances of survival post-metastasis.3,4

To determine if changes in UCDVA, UCIVA, UCNVA, and low-contrast CDVA (10% & 25%) post-phacoemulsification with PCIOLs are linked to preoperative HOA values.

IOL power calculation formulae incorporating posterior corneal power vs traditional keratometry in post-laser vision correction eyes undergoing cataract surgery