Sign in

Oscar Marcelo Lazo

@omlazo.science
234 followers 188 following 80 posts

Broad-spectrum neurobiologist, cancionista, & escribidor de brocha gorda. Dad of three humans, married to their unfathomable mum. I ask questions to neurons and brains at the UCL Queen Square Institute of Neurology 🇬🇧 and Universidad San Sebastián 🇨🇱.

PostsRepliesMedia
Oscar Marcelo Lazo @omlazo.science · 11/09/2026
010
Oscar Marcelo Lazo @omlazo.science · 10/09/2026
Malvinas, you mean? 🤦‍♂️
210
Reposted by Oscar Marcelo Lazo
The Washington Post @washingtonpost.com · 03/08/2026
The psychiatrist who helped popularize attachment theory says much of the conversation about attachment styles has drifted away from the science. Here's how they shape our interactions with others, and how to change them:
washingtonpost.com
Scientists say this is the reason some relationships flourish and others flop
How attachment styles influence our interactions with others — and how to change them.
1267
Oscar Marcelo Lazo @omlazo.science · 30/06/2026
Join THE NEW-ROTROPHIN and stay on top of the last literature about neurotrophic factors in health and disease, from molecular genetics and cell biology to clinical trials in cancer and neuroscience. It's free and community-driven. thenewrotrophin.base44.app/Newsletter
thenewrotrophin.base44.app
The NEW-rotrophin
Stay at the forefront of neurotrophic factor research. The newsletter delivers weekly curated updates on the latest publications, preprints, and news, keeping you informed and connected with the globa...
042
Reposted by Oscar Marcelo Lazo
EL PAÍS @elpais.com · 25/05/2026
Tribuna | "Las leyes de protección servirán de poco si la foto de un menor sigue siendo tratada como un bien que pertenece a todos menos a él", por Isabel Coixet social.elpais.com/3in…
01914
Oscar Marcelo Lazo @omlazo.science · 17/03/2026
Este viernes en el Campus Ciudad Universitaria de la @USanSebastian nos reunimos a celebrar el futuro de los adultos con síndrome de Down y a imaginarlo juntos. Filosofía, neurociencia y un panel de experiencias vividas. Inscríbete aquí: forms.office.com/r/t9CY8n4aR1
011
Reposted by Oscar Marcelo Lazo
Nature @nature.com · 24/02/2026
After nearly 3.5 years of deliberations, researchers concluded their independent assessment of the origin of the coronavirus SARS-CoV-2 go.nature.com/4qUxijx
go.nature.com
COVID’s origins: what we do and don’t know
Researchers summarize key insights from the world’s first comprehensive investigation into how a pandemic started.
04825
Oscar Marcelo Lazo @omlazo.science · 17/12/2025
El viernes pasado estuve en el programa #LaSociedadDeLaCiencia en Radio USACH, participando de una buena conversa transdisciplinaria sobre resiliencia. Mi hipótesis de trabajo es que tras las respuestas resilientes siempre hay un mecanismo de flexibilidad. Acá el video: youtu.be/kASttZIzCx4?...
youtu.be
Diplomacia científica y resiliencia: el nuevo mapa de la ciencia chilena | La Sociedad de la Ciencia
YouTube video by Radio Usach
000
Oscar Marcelo Lazo @omlazo.science · 19/11/2025
The end of an era for experimental psychology and emotions research. Hopefully his legacy and intellectual influence will keep his work alive far beyond today.
000
Oscar Marcelo Lazo @omlazo.science · 19/11/2025
Este viernes 21 desde las 9.30 am en FACSO, @uchile.bsky.social. Estaré hablando de organización y autonomía biológica, en el contexto de la cognición humana.
000
Oscar Marcelo Lazo @omlazo.science · 15/10/2025
Velan? 😂
010
Oscar Marcelo Lazo @omlazo.science · 15/10/2025
Ok, I get it.
010
Oscar Marcelo Lazo @omlazo.science · 15/10/2025
Don't quite get the difference between methods and protocols. Could you please expand?
100
Oscar Marcelo Lazo @omlazo.science · 10/10/2025
This may be an unpopular thing to say today, but Venezuela deserved a much better political opposition — and now it’s harder than ever for them to get one.
000
Reposted by Oscar Marcelo Lazo
Dementia Researcher @dementiaresearcher.bsky.social · 09/10/2025
Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London. www.dementiaresearcher.nihr.ac.uk/event/127th-...
dementiaresearcher.nihr.ac.uk
127th British Neuropathological Society meeting
Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.
012
Oscar Marcelo Lazo @omlazo.science · 09/10/2025
La democracia liberal patas pa arriba: un comercio no puede ponerle a sus clientes una regla de convivencia básica, como no portar armas visiblemente en el interior del súper, porque viola sus derechos constitucionales. ¡Jolín!
000
Reposted by Oscar Marcelo Lazo
Juan S. Bonifacino @juanbonifacino.bsky.social · 08/10/2025
Excited to share our latest manuscript by @saikat2025.bsky.social and an international team, reporting variants in the EARP- and GARP-interacting protein EIPR1 associated with a neurodevelopmental disorder. Will send you the PDF if you can’t access the article: academic.oup.com/brain/articl...
academic.oup.com
EIPR1 variants cause a neurodevelopmental disorder with endolysosomal and dense core vesicle defects
Abstract. EIPR1 (EARP-interacting protein 1, formerly known as TSSC1) is a WD40-domain protein that interacts with the EARP (endosome-associated recycling
0144
Oscar Marcelo Lazo @omlazo.science · 06/10/2025
Latinoamérica en El Tiny! youtu.be/UEqTIwRrWvA?...
youtu.be
31 Minutos: Tiny Desk Concert
YouTube video by NPR Music
000
Oscar Marcelo Lazo @omlazo.science · 30/09/2025
Join us today for a new session of our Journal Club on Psychology & Neuroscience —we are having a special guest, @tonchimatta.bsky.social, who comes to discuss her favourite bit of neuroscience: brain-machine interfaces and their potential.
010
Reposted by Oscar Marcelo Lazo
Michael E. Mann @michaelemann.bsky.social · 02/09/2025
#ScienceUnderSiege: How to Fight the Five Most Powerful Forces that Threaten Our World by @peterhotezmdphd.bsky.social & yours truly, comes out one week from today! 🙂 Preorder now: Barnes & Noble: www.barnesandnoble.com/w/science-un... Publisher: www.hachettebookgroup.com/titles/micha...
kirkus review: SCIENCE UNDER SIEGE
HOW TO FIGHT THE FIVE MOST POWERFUL FORCES THAT THREATEN OUR WORLD

by Michael E. Mann & Peter J. Hotez ‧ RELEASE DATE: Sept. 9, 2025

A necessary and propulsive argument that offers optimism in the face of one of the world’s most destructive forces.

Pursuing science and truth in the age of disinformation.

On the tail of a historic deadly pandemic, in the midst of a climate crisis that threatens the world, perhaps the greatest danger is the overwhelming rise of disinformation that threatens to crush and diminish science that might save us. With that, two renowned scientists—climatologist Mann and pediatrician and global health expert Hotez—who are veterans of the disinformation wars have come together to create a work that seeks to provide a way out. The authors identify what they call “the p’s”—five key forces creating a dangerous modern realm of anti-science: “the plutocrats, the authoritarian petrostates (assisted by polluters and the politicians who advocate for them), the ‘pros’ who use their professional (or in some cases scholarly) credentials to deceive or promote unsupported contrarian views, the propagandists who amplify them on social media and other venues, and, increasingly, the press, including even the mainstream press.” The narrative reveals, in compelling detail, how these forces weave a complicated web of public deception and political danger in the face of some of humanity’s greatest challenges. With clear-eyed prose moving through chapters that explain each of these actors, the authors provide a clear, persuasive road map to fight back against the forces that diminish and dismiss science. The result is an empowering work in a world that can often feel lost to untruths. “While there is urgency—unlike any we’ve ever known—there is still agency,” they write. “We can still avert disaster if we can understand the nature of the mounting anti-science threat and formulate a strategy to counter it.”
A necessary and pro…book cover
36129
Reposted by Oscar Marcelo Lazo
Oscar Marcelo Lazo @omlazo.science · 13/08/2025
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar. Lo ves aquí: pro.amorporlamarca.com/direct-surve...
022
Oscar Marcelo Lazo @omlazo.science · 13/08/2025
Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar. Lo ves aquí: pro.amorporlamarca.com/direct-surve...
022
Reposted by Oscar Marcelo Lazo
EL PAÍS @elpais.com · 06/08/2025
Editorial | "Las imágenes y los relatos del horror de Hiroshima y Nagasaki no son una conmemoración histórica más: sirven como recuerdo constante del daño existencial que la humanidad puede infligirse a sí misma"
elpais.com
La presencia de Hiroshima | Editorial
El 80 aniversario de la destrucción de la ciudad japonesa advierte contra la actual frivolidad global sobre la amenaza nuclear
42615
Oscar Marcelo Lazo @omlazo.science · 05/08/2025
Random chat last night... — Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one! — Do you know what a papilloma is? — No... — A cause of cancer — x___x — A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated. — Ok
000
Oscar Marcelo Lazo @omlazo.science · 01/08/2025
Tengo que hacer algunas clases este semestre. Afortunadamente son algunas de las cosas que más me entusiasman en el mundo, así que simplemente espero poder transferir algo de ese mismo entusiasmo. ¡Se viene el segundo semestre!
000
Oscar Marcelo Lazo @omlazo.science · 31/07/2025
I've been culturing intact explants of embryonic mouse basal forebrain. It's a pretty cool way to model interactions between the different BFN populations in vitro, both in physiology and disease, specially in Alzheimer's where these neurons are particularly vulnerable. [Confocal— DAPI+Phalloidin]
010
Oscar Marcelo Lazo @omlazo.science · 28/07/2025
This Thursday 31st/July at 3.30 pm we have another session of our Journal Club on Psychology and Neuroscience. This month we are led by Prof. @pauladagnino.bsky.social to discuss mental health outcomes monitoring in the public system. Join us!
010
Reposted by Oscar Marcelo Lazo
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 19/07/2025
Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons www.biorxiv.org/content/10.1101/202…
011
Oscar Marcelo Lazo @omlazo.science · 09/07/2025
I came across this concept today and I liked this blog post on epistemic respect and peer-review: blogs.lse.ac.uk/impactofsoci...
blogs.lse.ac.uk
For Epistemic Respect – Against Reviewer 2 - Impact of Social Sciences
Gorgi Krlev & Andre Spicer draw on an encounter with reviewer 2 and the subsequent twitterstorm, to explain what epistemic respect means and how to uphold it.
000
Oscar Marcelo Lazo @omlazo.science · 06/07/2025
Coming to London on a summer Saturday—when Pride celebrations were in full swing, and everyone was out with friends in all sorts of playful attire—has been absolutely vivifying!
010
Oscar Marcelo Lazo @omlazo.science · 25/06/2025
Tomorrow!
000
Oscar Marcelo Lazo @omlazo.science · 23/06/2025
I grew up one little bit today. I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door. Yeahp... getting old.
010
Reposted by Oscar Marcelo Lazo
Mike Fainzilber @mfainzilber.bsky.social · 07/06/2025
🙏 to editor Sian Lewis for this @natrevneuro.nature.com highlight on our recent paper www.nature.com/articles/s41...
nature.com
An intriguing role of repeat-element RNAs in nerve injury repair - Nature Reviews Neuroscience
A polyA-tail-directed RNA sequencing approach that was used to investigate transcriptomic changes in dorsal root ganglia following nerve crush revealed unexpected upregulation of a specific set of B2-...
043
Reposted by Oscar Marcelo Lazo
Alejandro Montenegro @aemonten.bsky.social · 27/05/2025
Today, in news that surprise no one... www.nature.com/articles/d41...
15219
Oscar Marcelo Lazo @omlazo.science · 27/05/2025
True that the promising story about jacifusen still requires more data to weight its impact in the real world, but I can't help thinking about the 16-y.o. kid with ALS that after a year of treatment is breathing again and recovering movement. Unprecedented progress! www.thelancet.com/journals/lan...
thelancet.com
Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series
The findings suggest the safety and possible efficacy of jacifusen for treating FUS-ALS. The efficacy of jacifusen is being further evaluated in an ongoing clinical trial.
020
Oscar Marcelo Lazo @omlazo.science · 22/04/2025
000
Oscar Marcelo Lazo @omlazo.science · 15/03/2025
I feel you. I hope you comprehend.
000
Oscar Marcelo Lazo @omlazo.science · 07/03/2025
😂 Qué talento.
010
Reposted by Oscar Marcelo Lazo
Walker Bragman @walkerbragman.bsky.social · 01/03/2025
If I were an elected Dem today, here’s what I’d be doing: - Not cooperating with anything administration wants to do. No bailing the GOP out. Shut it down. - Daily fireside chats explaining how/why I’m fighting. - Calling them fash. - Attending protests. Calling for protests (at their homes?)
13635155
Oscar Marcelo Lazo @omlazo.science · 01/03/2025
Actually, if I go higher up the nih.gov website doesn't work either. :/
nih.gov
National Institutes of Health (NIH)
Official website of the National Institutes of Health (NIH). NIH is one of the world's foremost medical research centers. An agency of the U.S. Department of Health and Human Services, the NIH is the ...
110
Oscar Marcelo Lazo @omlazo.science · 01/03/2025
Works for me, but the main domain of the NCBI doesn't:
100
Oscar Marcelo Lazo @omlazo.science · 23/02/2025
Asunto aparte es el declive de @theclinic.cl desde que fue adquirido por sus nuevos propietarios. Francamente triste. Ya nada es lo que era.
000
Oscar Marcelo Lazo @omlazo.science · 23/02/2025
Post transplataforma desde LinkedIn sobre los traspasos de capital de CORFO a las arcas fiscales, a propósito de un excelente comentario de Eduardo Bitrán: www.linkedin.com/posts/omlazo...
linkedin.com
101
Oscar Marcelo Lazo @omlazo.science · 20/02/2025
Corrected, just because it was a small molecule and not ASO. Equally transformative step forward! bsky.app/profile/omla...
000
Oscar Marcelo Lazo @omlazo.science · 20/02/2025
First splicing therapy in utero for spinal motor atrophy (SMA). Massive achievement.
0123
Oscar Marcelo Lazo @omlazo.science · 20/02/2025
True! My mistake. I assumed it was an ASO but when I went to the paper I realised it was a small molecule. Thanks for noting it! (I always wonder if these tiny compounds are really as specific as we want them to be)
010
Reposted by Oscar Marcelo Lazo
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 20/02/2025
Intracellular Trafficking SNARE Protein, Syntaxin-6, is a Modifier of Prion and Tau Pathogenesis in vivo and in Cellular Models www.biorxiv.org/content/10.1101/202…
001
Oscar Marcelo Lazo @omlazo.science · 20/02/2025
About to repeat the classic stories of cobras in Delhi and rats in Hanoi. People will breed mosquitoes for cash.
000
Oscar Marcelo Lazo @omlazo.science · 10/02/2025
Got baked beans from England just to pair them with Chilean merluza austral.
130
Reposted by Oscar Marcelo Lazo
Spang Lab @spanglab.bsky.social · 05/02/2025
Interested how events are coordinated during #endosome maturation? Check out our latest paper! Congrats Daniel, Samit and Jachen! www.embopress.org/doi/full/10....
embopress.org
Coordination between ESCRT function and Rab conversion during endosome maturation | The EMBO Journal
imageimageEarly endosome maturation requires Rab conversion and ESCRT function; however, how these processes are coordinated remains largely elusive. This study proposes that Rab conversion in both C....
0179