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Olivia Charmant

@oliviacharmant.bsky.social
68 followers 128 following 2 posts

Engineer in Molecular Biology (with a crush for Paramecium)

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Thomas Balan @thomasbalan.bsky.social · 08/04/2026
First first-author paper out! 🎉 We show that the classically repressive mark H3K27me3 can be linked to active transcription through a newly identified reader complex 🤯 Really grateful to everyone involved in this project during my PhD! Thread below 👇
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Reposted by Olivia Charmant
Thomas Balan @thomasbalan.bsky.social · 21/10/2025
🚨 Excited to share my first preprint on bioRxiv! 🎓 We uncover a non-canonical role of condensin I, beyond chromosome segregation 🧬 This work is the fruit of a collaboration between the @sandraduharcourt.bsky.social & @betermieri2bc.bsky.social labs! ➡️ doi.org/10.1101/2025...
doi.org
A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination
Prokaryotes and eukaryotes use diverse strategies to cope with invading mobile genetic elements, including programmed DNA elimination (PDE). In the ciliate Paramecium , elimination of transposable ele...
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Reposted by Olivia Charmant
sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 05/01/2026
Happy to begin the year with the publication of a Journal Club article - Programmed ‘DNA splicing’ removes transposons from genes. rdcu.be/eXBym
rdcu.be
Programmed ‘DNA splicing’ removes transposons from genes
Nature Reviews Molecular Cell Biology - A study that showed that programmed DNA elimination in somatic genomes of ciliates involves excision of intrusive, transposon-derived sequences from genes.
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Reposted by Olivia Charmant
sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 17/10/2025
Our latest paper on a histone methyltransferase-independent function of PRC2 controlling small RNA dynamics during programmed DNA elimination in Paramecium is now published in #NAR. #RNAbiology #TEsky #smallRNAs #PRC2 #DNAelimination 1/5 academic.oup.com/nar/article-...
academic.oup.com
A histone methyltransferase-independent function of PRC2 controls small RNA dynamics during programmed DNA elimination in Paramecium
Abstract. To limit transposable element (TE) mobilization, most eukaryotes have evolved small RNAs to silence TE activity via homology-dependent mechanisms
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Reposted by Olivia Charmant
Institut Jacques Monod @ijmonod.bsky.social · 26/08/2025
📢 PhD Thesis defense 📅 Sept. 19th 📍 IJM @thomasbalan.bsky.social ( @sandraduharcourt.bsky.social Lab ) will defend his PhD thesis "Characterization of proteins involved in the dynamics of histone modifications during programmed DNA elimination in Paramecium tetraurelia" ➡️ buff.ly/V8vzSsT
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Reposted by Olivia Charmant
sandraduharcourt.bsky.social @sandraduharcourt.bsky.social · 13/01/2025
Our #Paramecium artwork is featured on the cover of #NAR! doi.org/10.1093/nar/...
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Olivia Charmant @oliviacharmant.bsky.social · 18/12/2024
A brief overview of my latest project in the Duharcourt lab, highlighted by @cnrs.bsky.social and a sneak peek in the head of an artist (aka my sister) inspired by Paramecium.
insb.cnrs.fr
Tri sélectif des petits ARN : un enjeu pour préserver l’intégrité du génome
Dans un article publié dans Nucleic Acids Research, des scientifiques ont identifié un nouveau rôle pour la protéine
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Reposted by Olivia Charmant
Thomas Balan @thomasbalan.bsky.social · 25/11/2024
Very cool new paper from the lab, delving into sRNAs selective degradation enabling TE control! Congrats @oliviacharmant.bsky.social 🎉🎉
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Olivia Charmant @oliviacharmant.bsky.social · 25/11/2024
Sharing the good news that makes the PhD journey worth it! Check out our latest paper in collaboration with #JulitaGruchota published in #NAR.
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