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Alex O'Hare

@oharealex.bsky.social
28 followers 100 following 10 posts

Universitat de les Illes Balears, PhD Student Computational Neuroscience, Dynamical Systems, Basal Ganglia, Dopamine.

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Reposted by Alex O'Hare
Dan Goodman @neural-reckoning.org · 27/09/2026
SNUFA abstract submission is closed. Make sure to register for the conference if you would like to take part in voting for which abstracts get promoted from posters to talks!
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Masud Husain @masudhusain.bsky.social · 08/03/2026
March issue @brain1878.bsky.social with winning article in Brain Essay Competition by @oharealex.bsky.social considers if it is technologically feasible for machines to achieve human-level intelligence, and philosophically plausible for them to possess consciousness academic.oup.com/brain/articl...
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Alex O'Hare @oharealex.bsky.social · 07/03/2026
Honoured to have been selected as the winner for the Brain @brain1878.bsky.social 2025 Essay Competition! I look forward to developing these ideas in future work. academic.oup.com/brain/articl...
academic.oup.com
What lies beyond thy silicone face and silicon brain?
The rapid rise of large language models has fuelled speculation about eventual artificial general intelligence. Winner of the Brain Essay Competition 2025,
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Alex O'Hare @oharealex.bsky.social · 10/12/2025
Excited to be presenting work on topological communities in the human connectome with a poster at the @institutocajal.bsky.social next week! A collaborative effort, masterminded by @brigan.bsky.social!
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Reposted by Alex O'Hare
Dopamine Society @dopaminesociety.bsky.social · 27/11/2025
🚨🚨🚨DOPAMINE 2026! Abstract submission closes on December 1st! #Sevilla #Dopamine 👇🏻 dopaminesociety.org/abstracts/
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Louis-Eric Trudeau @louistrudeau.bsky.social · 04/08/2025
A very good read if you want to learn everything there is to know about dopamine. Take a look at chapter 4! www.sciencedirect.com/handbook/han...
sciencedirect.com
Handbook of Behavioral Neuroscience | Volume 32: The Handbook of Dopamine | ScienceDirect.com by Elsevier
Read the latest chapters of Handbook of Behavioral Neuroscience at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
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Blake Richards @tyrellturing.bsky.social · 31/07/2025
This is intetresting, paper argues that dopamine also encodes "action prediction errors", i.e. differences between actions you predict you will make and actions you do, regardless of reward. Could be used to reinforce habits for repetitive voluntary behaviours: www.nature.com/articles/s41... 🧠📈 🧪
nature.com
Dopaminergic action prediction errors serve as a value-free teaching signal - Nature
Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.
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Trends in Neurosciences @cp-trendsneuro.bsky.social · 30/07/2025
'Untangling the multifaceted VTA responses to stress' by Urszula Skupio, Alexander Harris & Abigail Polter @ampolter.bsky.social @dralexharris.bsky.social www.cell.com/trends/neuro...
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Trends in Neurosciences @cp-trendsneuro.bsky.social · 29/07/2025
'What would it take to prove that a chronic infection is a causal agent in Alzheimer’s disease?' by Randy Brutkiewicz, Wei Cao, David Morgan, Roberta Souza Dos Reis, Vidyani Suryadevara, Auriel Willette, Sara Willette, Season Wyatt-Johnson & Michael Duggan www.cell.com/trends/neuro...
cell.com
What would it take to prove that a chronic infection is a causal agent in Alzheimer’s disease?
Accumulating evidence over several years suggests that microbial infections (e.g., bacteria, viruses, fungi) may play a role in the etiology of Alzheimer’s disease (AD). In this review, we discuss the...
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Nature Neuroscience @natneuro.nature.com · 29/07/2025
Avatars who appear to be sick entering the peripersonal space in virtual reality are anticipated by multisensory–motor areas, activate the salience network, and trigger activation of innate lymphoid cells, mirroring responses seen in actual infections www.nature.com/articles/s41...
nature.com
Neural anticipation of virtual infection triggers an immune response - Nature Neuroscience
Serino et al. show that seeing an infectious avatar approach the body in virtual reality triggers an immune response, indicating that the brain prepares the body to fight infections even for perceived...
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Alex O'Hare @oharealex.bsky.social · 22/06/2025
Many thanks to the organizers and participators for another excellent informative conference on mathematical neuroscience. Now looking forward to the OCNS conference in Florence next month!
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Alex O'Hare @oharealex.bsky.social · 22/06/2025
When I first heard of chronotypes in passing conversation, my first thought was "this is surely pseudoscience". Ever since I discovered this is not the case, I have been absolutely fascinated by this subject which goes a long way in explaining individual differences in productivity and work routines
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Alex O'Hare @oharealex.bsky.social · 11/06/2025
Looking forward to exhibiting a novel computational model of dopamine at the ICMNS '25 conference in Barcelona next week! www.crm.cat/internationa... #ICMNS25 #Neuroscience
crm.cat
INTERNATIONAL CONFERENCE ON DYNAMICS IN SYSTEMS AND SYNTHETIC BIOL​OGY: SCHEDULE - Centre de Recerca Matemàtica
INTERNATIONAL CONFERENCE ON DYNAMICS IN SYSTEMS AND SYNTHETIC BIOL​OGY: SCHEDULE June 14th, 2021 June 15th, 2021 June 16th, 2021 June 17th, 2021 June 18th, 2021 MONDAY OF VIROLOGY AND IMMUNOLOGY TUESD...
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Reposted by Alex O'Hare
Armin Lak @laklab.bsky.social · 11/06/2025
Our work, out at Cell, shows that the brain’s dopamine signals teach each individual a unique learning trajectory. Collaborative experiment-theory effort, led by Sam Liebana in the lab. The first experiment my lab started just shy of 6y ago & v excited to see it out: www.cell.com/cell/fulltex...
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Alex O'Hare @oharealex.bsky.social · 13/05/2025
Looking forward to exhibit some work on synaptic dopamine dynamics at the OCNS conference in July this year! ocns.memberclicks.net/cns-2025_quick #OCNS25 #Neuroscience @cnsorg.bsky.social
ocns.memberclicks.net
CNS 2025
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Alex O'Hare @oharealex.bsky.social · 13/05/2025
Excited to be exhibiting a novel computational model of dopamine at the ICMNS '25 conference in Barcelona! www.crm.cat/internationa... #ICMNS25 #Neuroscience
crm.cat
International Conference on Mathematical Neuroscience | ICMNS25 - Centre de Recerca Matemàtica
ICMNS 2025 International Conference on Mathematical Neuroscience REGISTRATION FEE 300€ Standard registration 250€ Registration for postdocs 170€ Registration for students SCHEDULE ABSTRACTS CONTRIBUTE...
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Reposted by Alex O'Hare
Philip Ball @philipcball.bsky.social · 12/05/2025
Well well, as I suspected, you smart folks on Bluesky are unanimous in calling out this nonsense. (And N is pretty big in this informal survey!) And yet still these tech bros are given big platforms to spout this stuff, and the media (and some governments) love it. So we have a problem here, right?
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Patricia González-Rodríguez #NoScienceNoFuture👩🏻‍🔬 @pgonzalezrodriguez.bsky.social · 02/05/2025
🧠✨ Symposia submissions are NOW OPEN for Dopamine Meeting 2026! @DopamineSociety 📍Sevilla, Spain 📅 Open: May 1, 2025 ⏳ Deadline: June 16, 2025 Spread the word — don’t miss out! #Dopamine2026 dopaminesociety.org
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Jan Rosenow @janrosenow.bsky.social · 19/04/2025
Unthinkable just 10 years ago: Almost 3/4 of the EU’s electricity in 2024 was from renewable energy sources and nuclear. Gas and coal electricity generation is at record low levels.
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Emerson Harkin @efharkin.bsky.social · 27/03/2025
I'm excited to share that the last chapter of my PhD thesis is now published in Nature! 🍾 What drives serotonin neurons? We think it's the expectation of future reward and --- critically --- how fast this expectation is increasing. 📈 doi.org/10.1038/s415... 1/6
doi.org
A prospective code for value in the serotonin system - Nature
Merging ideas from reinforcement learning theory with recent insights into the filtering properties of the dorsal raphe nucleus, a unifying perspective is found explaining why serotonin neurons are ac...
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Philip Ball @philipcball.bsky.social · 06/03/2025
This looks really helpful, although TBH I'm surprised (sort of) to find the LLM community is debating the equivalent of whether simulated water is wet, or simulated black holes will suck the researchers in. Why would "I can simulate ToM responses" be interpreted as "I can create an AI with ToM"?
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Nature Neuroscience @natneuro.nature.com · 03/02/2025
An #astrocytic ensemble that emerges in the nucleus accumbens upon activity during cue-motivated behaviors and is essential for modulating cue-reward associations 🧪🧪 www.nature.com/articles/s41...
nature.com
Astrocyte ensembles manipulated with AstroLight tune cue-motivated behavior - Nature Neuroscience
Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective manipulation of tagged astrocyte...
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Kevin Mitchell @wiringthebrain.bsky.social · 26/02/2025
Full-on eugenics, in its most rabid, racist form is oozing its way back into mainstream discourse.
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Nature @nature.com · 24/02/2025
Nature research paper: An opponent striatal circuit for distributional reinforcement learning go.nature.com/41a7Snf
go.nature.com
An opponent striatal circuit for distributional reinforcement learning - Nature
D1- and D2-expressing striatal neurons encode separate parts of a learned reward distribution, paralleling modern approaches in machine learning.
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Philip Ball @philipcball.bsky.social · 17/02/2025
The case for proper scientific study of unidentified flying and subsea objects. Whatever you think of that, this long paper is full of fascinating case histories. www.arxiv.org/abs/2502.06794
arxiv.org
The New Science of Unidentified Aerospace-Undersea Phenomena (UAP)
After decades of dismissal and secrecy, it has become clear that a significant number of the world's governments take Unidentified Aerospace-Undersea Phenomena (UAP), formerly known as Unidentified Fl...
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Carolina Rezaval @crezaval.bsky.social · 12/02/2025
Dopamine-serotonin push-pull balances reward seeking and caution. www.nature.com/articles/s41... Happy to comment on this cool study in mammals and the parallels with our own work in #Drosophila! www.thetransmitter.org/learning/dop...
thetransmitter.org
Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning
Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin, a new study shows.
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